Başlık için Temel Tıp Bilimleri Bölümü Makale Koleksiyonu listeleme
Toplam kayıt 65, listelenen: 22-41
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Death receptor-dependent apoptosis and cell cycle delay induced by bioymifi in human cervical cancer cells
(2022)Abstract: In chemotherapy applied against cervical cancer, non-specific cytotoxicity and drug resistance that develops over time are trying to be overcome. Therefore, the development of effective and innovative chemotherapeutic ... -
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 2023/3/5)The main aims of anticancer drug development studies is to reduce the toxicity of the developed com pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ... -
Experimental and theoretical insights about the effect of some newly designed azomethine group‐contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 2023/8/5)We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ... -
Experimental, DFT and MD simulation studies of Mordant Black 11 dye adsorption onto polyaniline in aqueous solution
(Journal of Molecular Liquids, 2022)vjv -
Expression levels of BAP1, OGT, and YY1 genes in patients with eyelid tumors
(De Gruyter, 2021)Objectives: The aim of this study was to investigate BAP1, OGT and YY1 genes and protein levels in 12 samples (8 males, 4 females) of eyelid tumor tissue with basal cell carcinoma (BCC) and 12 normal control subjects ... -
Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization
(2021)Abstract Background: MicroRNAs (miRNAs) are small RNA molecules that modulate post-transcriptional gene regulation. They are often used as promising non-invasive biomarkers for the early diagnosis of cancer. However, ... -
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats
(Elsevier, 2022)The toxicity of acetaminophen (N-acetyl-para-aminophenol (APAP)) is the most frequent cause of drug-induced liver damage. Galium aparine L. (GA) is traditionally used to treat jaundice. We aimed to investigate the ... -
Hypothalamo-pituitary insufficiency associated with ectrodactyly-ectodermal dysplasia-clefting syndrome
(2009)Ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome is characterized by ectodermal dysplasia, ectrodactyly and facial clefting with multiple congenital anomalies such as urinary tract anomaly, lacrimal duct obstruction, ... -
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 28.09.2023)We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were ... -
Increased endoplasmic reticulum stress might be related to brain damage in hepatic ischemia-reperfusion injury
(2023)Objectives: Our study aimed to investigate the role of endoplasmic reticulum stress (ER) in brain damage following hepatic ischemia-reperfusion (HIR) injury. Specifically, we characterized the expression of markers of ... -
Investigating the Healing Effect of Hyperici Oleum and Triticum vulgare on Septal Perforation in Rats: A Preliminary Study
(2023)Objective: The aim of this study was to investigate histopathologically the possible beneficial effects of hyperici oleum and Triticum vulgare, having anti-inflammatory, antioxidant, and antiproliferative properties, on ... -
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(Bentham Science Publishers, 01.12.2023)Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body. Objectives: In this study, we aimed to investigate the relationship ... -
Investigation of the mechanisms involved in anticancer effect of glucosamine sulfate on SH-SY5Y cell line
(Bratislavske lekarske listy, 2022)Aim: Glucosamine derivatives have been found to have anticancer effects in many cancer cell lines in previous investigations. The effect of glucosamine sulfate on neuroblastoma, however, is uncertain. The potential cytotoxic ... -
ISI ŞOK PROTEİN 70 (HSP70) VE KANSER
(Efe Akademik Yayıncılık, 2022)Kardiyovasküler hastalıklardan sonra ikinci sıradaki ölüm nedeni olarak gösterilen kanserin, insidansı ve ölüm oranı tüm dünyada hızla artmaktadır. Amerikan Kanser Derneği'nin yakın tarihli bir raporuna göre, 2020'de ... -
Leukotriene metabolism and proiflammatory cytokines in Crimean Congo hemorrhagic fever
(01.01.2023)Crimean–Congo hemorrhagic fever (CCHF) is an emerging acute viral infection disease, yet its pathophysiology remains largely uncharacterized. Lipid mediators are molecules that play numerous roles in the physiologic and ... -
Long noncoding RNA expression analysis in Crimean Congo hemorrhagic fever patients
(Wiley, 2022)Crimean Congo hemorrhagic fever (CCHF) is an acute viral infection that can cause death. The detection of host transcriptome is important for understanding differences in the pathogenesis of the disease. Long noncoding ... -
Medical Students' Views and Attitudes toward Vaccine Refusal during the COVID-19 Pandemic: A Multicenter Study
(20.04.2024)Background: The rapid development and production of COVID-19 vaccines have raised concerns about their safety and efficacy, which have contributed to vaccine hesitancy among some people. Objectives: This study aimed to ... -
Melatonin levels and microRNA (miRNA) relative expression profile in the follicular ambient microenvironment in patients undergoing in vitro fertilization process
(2021)Abstract Purpose Intrafollicular fluid (IFF) melatonin plays a decisive role in maintaining granulosa cells’ DNA integrity and protects them against apoptosis. It reduces oxidative stress and improves the oocyte quality ... -
Mitochondrial Homeostasis and Mast Cells in Experimental Hepatic Ischemia-Reperfusion Injury of Rats.
(2022)Background: Ischemia-reperfusion injury is a histopathological event and is an important cause of morbidity and mortality after hepatobiliary surgery. We aimed to investigate the protective effect of uridine on hepatic ... -
MİDE KANSERİ VE HÜCRE KÜLTÜRÜ
(Efe Akademik Yayıncılık, 2022)Mide kanseri, gastrointestinal tümörlere neden olan, insan hayatı ve sağlığı için ciddi bir tehdit oluşturan yaygın bir hastalıktır. Hücre kültürü tekniği, diğer birçok kanser türünde olduğu gibi, mide kanseri ...
