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Preventive effects of Capparis Spinose extract on experimental periodontitis in rats: a histopathological and biochemical study
(2023)
This study aimed to assess the effectiveness of Capparis Spinose (CS) in preventing the initiation and pro gression of experimental periodontitis and to evaluate the effect of its on systemic oxidative stress in rats by ...
The Turkish version of the problem areas in diabetes-parents of teens (P-PAID-T): Cross-cultural adaptation, reliability, and validity
(10.08.2023)
Objective: To examine the Turkish validity and reliability of the Problem Areas in Diabetes- Parents of Teens (PPAID-T) scale and its psychometric properties for determining the parents’ diabetes-related distress.
Methods: ...
The experiences and thoughts of Turkish family physicians about COVID-19 pandemic: A qualitative study
(14.02.2023)
Background: Efforts to contain the SARS-CoV-2 virus would fall short without strong primary health
care.
Objectives: In this study, we aimed to determine the experiences, views and suggestions of
family physicians ...
The Effect of Cycle Threshold Value on Predicting Prognosis in CrimeanCongo Hemorrhagic Fever Disease
(22.12.2023)
Introduction: Crimean-Congo hemorrhagic fever (CCHF) disease is characterized by symptoms such as fever, headache, muscle aches, and bleeding. In severe cases, it can lead to death. Clinical and biochemical parameters, ...
Medical Students' Views and Attitudes toward Vaccine Refusal during the COVID-19 Pandemic: A Multicenter Study
(20.04.2024)
Background: The rapid development and production of COVID-19 vaccines have raised concerns about their safety and efficacy, which have contributed to vaccine hesitancy among some people.
Objectives: This study aimed to ...
Antimicrobially effective protein-loaded metal chelated chitosan composite
(1 Ağustos )
The immobilization of lysozyme onto a novel
synthetic metal chelator composite based on chitosan/
PAA-PMA (chitosan/acrylamide-maleic acid) and its effect
on antimicrobial activity were the aim of the current
study. ...
Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)
Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ...
Experimental and theoretical insights about the effect of some newly designed azomethine group‐contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 2023/8/5)
We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 2023/3/5)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed com pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In
recent years, ...
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 28.09.2023)
We herein report the determination of the cytotoxic activity and expression profiles of
some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The
studied novel compounds were ...