Temel Tıp Bilimleri Bölümü Makale Koleksiyonu: Recent submissions
Now showing items 41-60 of 65
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Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
(John Wiley & Sons Ltd, December 2)Benzimidazole type N-heterocyclic carbene molecules and their metal complexes have well-known biological activity. Elemental silver and silver complexes also have antibacterial and antifungal activity. In this study, ... -
Long noncoding RNA expression analysis in Crimean Congo hemorrhagic fever patients
(Wiley, 2022)Crimean Congo hemorrhagic fever (CCHF) is an acute viral infection that can cause death. The detection of host transcriptome is important for understanding differences in the pathogenesis of the disease. Long noncoding ... -
The relationship between serum prolidase activity and histone H3 protein levels and fibromyalgia
(VERDUCI PUBLISHERVIA GREGORIO VII, ROME 186-00165, ITALY, 2022)OBJECTIVE: Fibromyalgia (FM) is a clinical syndrome characterized by prominent physical and psychological impairment and widespread pain on both sides of the body, above and below the waist, and along the axial skeleton. ... -
Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model
(NEUROLOGICAL RESEARCH, 2022)khg -
Experimental, DFT and MD simulation studies of Mordant Black 11 dye adsorption onto polyaniline in aqueous solution
(Journal of Molecular Liquids, 2022)vjv -
Validation of Friedewald, Martin-Hopkins and Sampson low-density lipoprotein cholesterol equations
(2022/5/13)Background: Low-density lipoprotein cholesterol (LDL-C) is an important biomarker for determining cardiovascular risk and regulating lipid lowering therapy. Therefore, the accurate estimation of LDL-C concentration is ... -
The use of laboratory parameters and computed tomography score to determine intensive care unit requirement in COVID-19
(2021)Objectives It is vital to determine the intensive care unit (ICU) requirement at an early stage to reduce the mortality rate in COVID-19 patients. The aim of the study was to find reliable predictive markers to determine ... -
Understanding the pathophysiological changes via untargeted metabolomics in COVID‐19 patients
(Wiley, 2021 Nisan)Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease caused by a new strain of the coronavirus. There is limited data on the pathogenesis and the cellular responses of COVID-19. In this study, we aimed ... -
A novel therapeutic approach to NASH: Both polyethylene glycol 3350 and lactulose reduce hepatic inflammation in C57BL/6J mice.
(2021)Background. The gut-liver axis is one of the most emphasized topics in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Intestinal microbiota dysbiosis has been shown to be a predictor of disease severity and ... -
Mitochondrial Homeostasis and Mast Cells in Experimental Hepatic Ischemia-Reperfusion Injury of Rats.
(2022)Background: Ischemia-reperfusion injury is a histopathological event and is an important cause of morbidity and mortality after hepatobiliary surgery. We aimed to investigate the protective effect of uridine on hepatic ... -
Assessment of semaphorin 3A and semaphorin 7A levels in primary Sjogren's syndrome
(Springer, 2022/8/28)Sjogren's syndrome (SS) is a chronic autoimmune connective tissue disease. Varying rates of system involvements may be seen in the course of the disease. Semaphorins has multifunctions in several physiological and pathological ... -
Melatonin levels and microRNA (miRNA) relative expression profile in the follicular ambient microenvironment in patients undergoing in vitro fertilization process
(2021)Abstract Purpose Intrafollicular fluid (IFF) melatonin plays a decisive role in maintaining granulosa cells’ DNA integrity and protects them against apoptosis. It reduces oxidative stress and improves the oocyte quality ... -
Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization
(2021)Abstract Background: MicroRNAs (miRNAs) are small RNA molecules that modulate post-transcriptional gene regulation. They are often used as promising non-invasive biomarkers for the early diagnosis of cancer. However, ... -
Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome
(CMB Association Publiher, 2021)Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion ... -
Expression levels of BAP1, OGT, and YY1 genes in patients with eyelid tumors
(De Gruyter, 2021)Objectives: The aim of this study was to investigate BAP1, OGT and YY1 genes and protein levels in 12 samples (8 males, 4 females) of eyelid tumor tissue with basal cell carcinoma (BCC) and 12 normal control subjects ... -
Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
(Elsevier, 15/09/2021)In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new compounds were characterized ... -
Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes†
(The Royal Society of Chemistry, 2 November)Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals. Inhibition ... -
Adaptation of the evidence-based practices attitude scale-15 in Turkish family medicine residents
(Wiley, 08.2021)Aims: Aim of this study is to translate and apply a cross-cultural adaptation of the Evidence-Based Practice Attitude Scale (EBPAS) in Turkish and investigate its validity and reliability. Methods: The original EBPAS-15 ... -
Breastfeeding frequency of primary healthcare professionals and effective factors
(Wiley, 10.2021)Background: To determine the frequency of breastfeeding of mothers working in primary care, the differences between different employment groups, and the effective factors. Methods: This descriptive research study was ... -
Chemical and biological characterization of sulfated chitosan oligomer as heparin mimics
(Polymers and Polymer Composites, November 2)In the present study, chitosan oligomer was modified to sulfated chitosan oligomer (ShCsO) to mimic heparin. Its chemical structure was determined by infrared spectroscopy (FT-IR), X-ray diffractometry (XRD), differential ...