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Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure
(BMC, 2016)
Substantial attention and resources have been directed to improving outcomes of patients with critical illnesses, in particular sepsis, but all recent clinical trials testing various interventions or strategies have failed ...
Mortality and acute exacerbation of COPD: a pilot study on the influence of myocardial injury
(EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2017)
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Cardiohepatic interactions in heart failure
(TURKISH SOC CARDIOLOGY, 2013)
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Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
(WILEY, 2017)
Organ injury and impairment are commonly observed in patients with acute heart failure (AHF), and congestion is an essential pathophysiological mechanism of impaired organ function. Congestion is the predominant clinical ...
Recommendations on pre-hospital & early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine
(WILEY, 2015)
Acute heart failure is a fatal syndrome. Emergency physicians, cardiologists, intensivists, nurses and other health care providers have to cooperate to provide optimal benefit. However, many treatment decisions are ...
Renal Effects of Levosimendan: A Consensus Report
(SPRINGER, 2013)
Renal dysfunction is common in clinical settings in which cardiac function is compromised such as heart failure, cardiac surgery or sepsis, and is associated with high morbidity and mortality. Levosimendan is a calcium ...
In vivo and in vitro evidence for pleiotropic effects of levosimendan in the intensive care setting
(BIOMED CENTRAL LTD, 2011)
Levosimendan, in addition to its inotropic properties, could have anti-inflammatory and anti-oxidative properties, and can potentially decrease the deleterious effects of reactive oxygen species on the tissues. In their ...
Searching for an ideal hemodynamic marker to predict short-term outcome in cardiogenic shock
(BMC, 2009)
Cardiogenic shock is a lethal condition. Physicians are searching for hemodynamic markers which could help risk-stratification of patients in this picture. Torgersen and coworkers present an hourly time integral of the ...