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INVESTIGATION OF THE ANTIPROLIFERATIVE EFFECT OF SALVIA CADMICA ON COLON CANCER
(07.05.2023)
Salvia cadmica is an endemic species known to have antioxidant, antimicrobial and aromatic
properties and the existence of Salvia species is known to date back to 753 BC. This species,
whose medicinal properties were ...
Biologically active phthalocyanine metal complexes: Preparation, evaluation of α‐glycosidase and anticholinesterase enzyme inhibition activities, and molecular docking studies
(Wiley-VCH GmbH, Weinheim, 2021/6)
In this study, preparation, as well as investigation of α‐glycosidase and cholinesterase
(ChE) enzyme inhibition activities of furan‐2‐ylmethoxy‐substituted compounds
1–7, are reported. Peripherally, tetra‐substituted ...
Imidazole‐hydrazone derivatives: Synthesis, characterization, X‐ray structures and evaluation of anticancer and carbonic anhydrase I–II inhibition properties
(Chemistry Europe, 2023/7/20)
The nine new imidazole-hydrazone derivatives of Schiff base
were synthesized from the condensation reactions of 1-methyl1H-imidazole-2-carbaldehyde with various substitutedhydrazide derivatives. Structures of the final ...
Design, synthesis and biological evaluation of novel ketone derivatives containing benzimidazole and 1,3,4-triazole as CA inhibitors
(03.10.2023)
In this study, we synthesized a series of new benzimidazole-triazole (6a-6k) derivatives and characterized them by 1 H NMR, 13C NMR, and HRMS. These compounds were evaluated for their inhibitory activity against hCA-I and ...
Isatin/thiosemicarbohydrazone hybrids: Facile synthesis, and their evaluation as anti-proliferatıve agents and metabolıc enzyme inhibitors
(AJOL, 2023/7/3)
We are reporting a novel series of thiosemicarbazone derivatives derived from isatin (1-6), structural determination, and investigation of the inhibitory properties against proliferative, carbonic anhydrase, and cholinesterase ...
IMMUNOTHERAPY IN CANCER TREATMENT
(31.06.2023)
Cancer, which causes the death of approximately 10 million people
every year, is a type of disease that begins to spread to other parts of the body
by uncontrolled proliferation of cells in the tissues and organs of our ...
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(Wiley-VCH GmbH, Weinheim, 2021/4)
A new class of cyanopyridine derivatives (10a–e and 11a–e) containing the
phenylurea unit was synthesized and tested against some metabolic enzymes
including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), ...
Use of newly synthetized magnetic Fe3O4 nanoparticles modified with hexadecyl trimethyl ammonium bromide for the sensitive analysis of antidepressant drugs, duloxetine and vilazodone in wastewater and urine samples
(RSC, 17th June )
A new enrichment and determination method involving HPLC-DAD analysis following magnetic solidphase
extraction (MSPE) was developed to detect trace amounts of two antidepressant drugs, namely,
duloxetine (DUL) and ...
Application of magnetic solid‑phase extraction for sensitive determination of anticancer drugs in urine by means of diamino benzidine tetrachlorohydrate modified magnetic nanoparticles
(Şubat, 202)
Background The analysis of drug active molecules and residues in the treatment of cancer is important for the sustainability of
human life and therapeutic effects. For this purpose, a new magnetic sorbent was developed ...
Azinphos-methyl and chlorfenvinphos pesticides determination using fabric phase sorptive extraction followed by high performance liquid chromatography-photodiode array detector
(Elsevier, 25 April 2)
A reliable and efficient fabric phase sorptive extraction method was developed for the rapid analysis of azinphosmethyl
and chlorfenvinphos pesticide residues in wastewater and fruit juice samples using high-performance
liquid ...