Ara
Toplam kayıt 114, listelenen: 11-20
Pulicaria Gaertn. Cinsinin Bazı Türleri Üzerinde Yapılan Güncel Araştırmalar
(Gece Kitaplığı, Eylül 2021)
Pulicaria cinsi Asteraceae familyası içerisinde yer almaktadır ve ilk
kez 1791 yılında Gaertner tarafından tanımlanmıştır. Asya, Avrupa, Afrika
ve Arap yarımadasında dağılım göstermektedir (Anderberg, 2009).
Yeryüzünde ...
Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
(2021/9/15)
DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ...
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
(Elsevier, 1 November)
Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ...
BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
(2021/6)
In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ...
Synthesis of (4R)-2-(3-hydroxyphenyl)thiazolidine 4-carboxylic acid substituted phthalocyanines: Anticancer activity on different cancer cell lines and molecular docking studies
(2021)
In this study, firstly, (4R)-2-(3-hydroxyphenyl)thiazolidine-4-carboxylic acid (1)
and (4R)-2-(3-(3,4-dicyanophenoxy)phenyl)thiazolidine-4-carboxylic acid (2)
were prepared. Then, the novel type metallophthalocyanines ...
Tetra-substituted phthalocyanines bearing thiazolidine derivatives: synthesis, anticancer activity on different cancer cell lines, and molecular docking studies
(2021)
In the first step, (4R)-2-(2-hydroxyphenyl)thiazolidine-4-carboxylic acid (c) and 2-(2-(3,4-dicyano phenoxy)phenyl)thiazolidine-4-carboxylic acid (1) were prepared. Then, the peripherally tetra-substituted
metallophthalocyanines ...
Potential role of immune cell genetic variants associated with tumor microenvironment response in laryngeal squamous cell carcinoma (LSCC) in terms of clinicopathological features
(20 October)
Immunomodulatory signals regulate the self-tolerance, activation, priming and survival processes of T cells.
Programmed cell death protein 1 (PD1), Programmed death-ligand 1 (PD-L1) inhibitory signals and CD27, CD28 ...
Circulating serum miR-200c and miR-34a-5p as diagnostic biomarkers for endometriosis
(2021)
Objective: Endometriosis is defined by the presence of endometrial glands and stroma grow in areas
outside the uterus. A simple blood test for endometriosis-specific biomarkers would offer a more timely
accurate diagnosis ...
Design, synthesis and biological evaluation of novel bischalcone derivatives as potential anticancer agents
(1April 202)
Building on our previous work that discovered chalcone as a promising pharmacophore for anticancer activity,
we have various other chalcone derivatives and have synthesized a series of novel bischalcone to explore their ...
Biomarker potentials of miRNA‑associated circRNAs in breast cancer (MCF‑7) cells: an in vitro and in silico study
(2021)
Breast cancer is a heterogeneous disease, which is the most common malignancy in women. The incidence and mortality
rates of breast cancer indicate that it is the leading cause of cancer-related with deaths. circRNAs ...