Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Author "Doğan, Murat"
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Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds
Koçyiğit,Ümit M.; Doğan, Murat; Muğlu, Halit; Taslimi, Parham; Tüzün,Burak; Yakan,Hasan; Bal, Halil; Güzel,Emre; Gülçin,İlhami (Elsevier, 2022/09/15)Design, synthesis, structural elucidation, and investigation of cytotoxic and antimicrobial activity, butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzyme inhibition effects of isatinthiosemicarbazone ... -
Synthesis and biological evaluation of thiosemicarbazone derivatives
Doğan, Murat; Koçyiğit,Ümit M.; Gürdere,Meliha B.; Ceylan,Mustafa; Budak,Yakup (Springer US, 2022/07/21)In this study, firstly, 22 thiosemicarbazone derivatives (3a-y) were synthesized. Then, ADME parameters, pharmacokinetic properties, drug-like structures, and suitability for medicinal chemistry of these molecules were ... -
Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives
Tapera,Michael; Kekeçmuhammed, Hüseyin; Tüzün,Burak; Sarıpınar,Emin; Koçyiğit,Ümit M.; Yıldırım,Ebrar; Doğan, Murat; Zorlu, Yunus (Elsevier, 2022/12/05)A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a condensation reaction between indoline-2,3-dione (isatin) and 2-benzylidenehydrazinecarboximidamide derivatives. The structure of compounds ...