Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Author "Gülçin,İlhami"
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Arylated quinoline and tetrahydroquinolines: Synthesis, characterization and their metabolic enzyme inhibitory and antimicrobial activities
Koçyiğit,Ümit M.; Ökten,Salih; Çakmak, Osman; Gizem, Burhan; Ataş,Mehmet; Taslimi, Parham; Gülçin,İlhami (Chemstry Europa, 2022/10/07)The aims of this study are to synthesize and characterize some new phenyl quinoline derivatives and to determine the activities of them and the recently prepared substituted phenyl quinolines against Acetylcholinesterase ... -
Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds
Koçyiğit,Ümit M.; Doğan, Murat; Muğlu, Halit; Taslimi, Parham; Tüzün,Burak; Yakan,Hasan; Bal, Halil; Güzel,Emre; Gülçin,İlhami (Elsevier, 2022/09/15)Design, synthesis, structural elucidation, and investigation of cytotoxic and antimicrobial activity, butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzyme inhibition effects of isatinthiosemicarbazone ... -
Phthalocyanine complexes with (4-isopropylbenzyl) oxy substituents: preparation and evaluation of anti-carbonic anhydrase, anticholinesterase enzymes and molecular docking studies
Güzel,Emre; Koçyiğit,Ümit M.; Taslimi, Parham; Gülçin,İlhami; Erkan Sultan; Nebioğlu, Mehmet; Arslan,Barış S; Şişman,İlkay (Taylor & Francis, 2022/01/26)n this study, the preparation, aggregation behavior and investigation of carbonic anhydrase and cholinesterase enzyme inhibition features of non-peripherally (4-isopropylbenzyl)oxy-substituted phthalocyanines (4–6) are ... -
Potential thiosemicarbazone‐based enzyme inhibitors: Assessment of antiproliferative activity, metabolic enzyme inhibition properties, and molecular docking calculations
Yakan,Hasan; Koçyiğit,Ümit M.; Muğlu, Halit; Ergul,Mustafa; Erkan,Sultan; Güzel,Emre; Taslimi, Parham; Gülçin,İlhami (Taylor & Francis, 2022/01/26)A new series of thiosemicarbazone derivatives (1–11) were prepared from various aldehydes and isocyanates with high yields and practical methods. The structures of these compounds were elucidated by Fourier transform ...