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Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
(EYLÜL 2023)
Abstract: Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene]
silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1-
methallyl-3-(3,4,5 ...
Synthesis of Bis-Nicotinonitrile Derivatives and Investigations of Antimicrobial and Antibiofilm Activities
(Ekim 2023)
In this study aimed to the synthesis of novel bis-nicotinonitrile derivatives starting from 1,3-bis-chalcones and investigate their antimicrobial activity potentials. Bis-nicotinonitrile derivatives were synthesized from ...
Imidazole‐hydrazone derivatives: Synthesis, characterization, X‐ray structures and evaluation of anticancer and carbonic anhydrase I–II inhibition properties
(19.06.2023)
The nine new imidazole-hydrazone derivatives of Schiff base
were synthesized from the condensation reactions of 1-methyl1H-imidazole-2-carbaldehyde
with various substitutedhydrazide
derivatives. Structures of the final ...
Design, synthesis, and molecular docking studies of benzimidazole‐1,3,4‐triazole hybrids as carbonic anhydrase I and II inhibitors
(30.08.2023)
In this study, with an aim to develop novel heterocyclic hybrids as potent enzyme
inhibitors, we synthesized a series of 10 novel 2- (4- (4- ethyl- 5- (2- (substitutedph
enyl)- 2- oxo- ethylthio)- 4H- 1,2,4- triazol- 3- ...
Synthesis and Molecular Docking of New N-Acyl Hydrazones- Benzimidazole as hCA I and II Inhibitors
(20.01.2023)
Background: The carbonic anhydrases (CAs) which are found in most living organisms is a member of the zinc-containing metalloenzyme family. The abnormal levels and activities are frequently associated with various diseases ...
Synthesis, and docking studies of novel tetrazole-S-alkyl derivatives as antimicrobial agents
(07.01.2023)
A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their
antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC
22019) and ...
Synthesis, biological evaluation and in silico studies of novel thiadiazole-hydrazone derivatives for carbonic anhydrase inhibitory and anticancer activities
(04.08.2023)
ABSTRACT
Thiadiazole and hydrazone derivatives (5a–5i) were synthesized
and their chemical structures were verified and described by
1
H NMR,
13
C NMR, and HRMS spectra. Three cancer cell lines
(MCF-7, MDA, and ...
Use of newly synthetized magnetic Fe3O4 nanoparticles modified with hexadecyl trimethyl ammonium bromide for the sensitive analysis of antidepressant drugs, duloxetine and vilazodone in wastewater and urine samples
(2023)
A new enrichment and determination method involving HPLC-DAD analysis following magnetic solidphase
extraction (MSPE) was developed to detect trace amounts of two antidepressant drugs, namely,
duloxetine (DUL) and ...
Use of Fe3O4@MPTMS-Dithizone Magnetic Nanoparticles as Solid Phase Sorbent for Sensitive Analysis of Sibutramine Molecules in Herbal Slimming Products
(Bentham Science Publishers, June 07, 2)
Abstract: Background: A new enrichment and sensitive determination method, which includes HPLCDAD
analysis after Magnetic Solid Phase Extraction (MSPE), has been developed for trace analysis of
Sibutramine molecules in ...
New benzimidazole‐oxadiazole derivatives: Synthesis, α‐glucosidase, α‐amylase activity, and molecular modeling studies as potential antidiabetic agents
(23.01.2023)
Benzimidazole‐1,3,4‐oxadiazole derivatives (5a–z) were synthesized and characterized
with different spectroscopic techniques such as
1
HNMR,
13
CNMR,andHRMS.The
synthesized analogs were examined against α‐glucosidase ...