Resections in liver metastases: Basic principles and surgical approach in ovarian origin metastases: Review [Karaci?er metastazlarinda rezeksiyon: Genel prensipler ve over kökenli metastazlarda cerrahi yaklaşim]

Abstract

Despite many studies about resection of metachronous colorectal liver metastases, there are limited data on the effectiveness of resection of ovarian liver metastases in the literature. However, obtaining best results from surgical treatment of liver metastases of colorectal origin has encouraged clinicians to resect liver metastases of ovarian origin. 5-year survival rate in patients underwent liver resection for colorectal metastases varies between 35% and 40%. However, most of patients having metastatic liver have unresectabl disease and only few patients canditate for resection. Presence of extrahepatic disease and positive surgical margings after resection are related to unfavorable prognosis and increased recurrence. In ovarian cancer, synchronous or metachronous paranchimal liver metastasis is associated with advanced stage, aggressive tumor behaviour and poor prognosis. This group of patients, therefore, have not been found an appropriate canditade for cytoreductive surgery for a long time. After resection of ovarian liver metastateses, mean survival varies between 7 and 94 months with reported the mean 26.3 months in a lage series. However, any liver resection performed for liver metastasis by colorectal, ovarian or other origines is a procedure which requires advanced surgical knowledge and skill. In this paper, basic principles, techniques and oncological results of, and alternatives to liver resection for ovarian cancer liver metastases are reviwed. Copyright © 2012 by Türkiye Klinikleri.