Early thrombosis in bovine mesenteric vein grafts after infrainguinal reconstruction

Abstract

INTRODUCTION: Autologous vein grafts are still the gold standard in infrainguinal arterial bypass grafting procedures. However, due to the unavailability of suitable autologous vein grafts, heterogeneous grafts are usually preferred. In the present study, surgical outcomes with bovine mesenteric vein grafts (ProCol, Hancock Jaffe Laboratories, USA) in the infrainguinal location in patients with ischemic leg infection or necrosis are presented. METHODS: Seven patients who underwent infrainguinal arterial reconstructions with ProCol grafts were evaluated retrospectively. RESULTS: Graft thrombosis was seen in two patients on postoperative day 1 (28.5%). The shortest and the longest patency durations were six and 18 months, respectively. Aneurysmal dilation developed postopera-tively in two grafts (28.5%) after 12 and 18 months, respectively. CONCLUSION: In cases where infection accompanies ischemia, and autologous veins are not available as graft materials, ProCol grafts can be used as temporary grafts in infrainguinal arterial reconstructions. The use of the graft is believed to be unacceptable for any indication other than infection due to its low short-and long-term patency rates and high risk of aneurysm formation in this location. © 2008 Pulsus Group Inc. All rights reserved.