Browsing Moleküler Biyoloji ve Genetik Bölümü Makale Koleksiyonu by Author "0000-0002-3925-3430"
Now showing items 1-3 of 3
-
BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
Bağda, Efkan; Harmandar, Kevser; Bağda, Esra; Şahin, Gamze; Karakodak, Nurşen; Durmuş, Mahmut; Khezami, Khaoula (Springer, 2021/05/04)In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ... -
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
Bağda, Efkan; Bağda, Esra; Durmuş, Mahmut; Yılmaz, Hasan Emre (Elsevier, 2021/11/1)Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ... -
Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
Bağda, Efkan; Bağda, Esra; Koçak, Abdulkadir; Durmuş, Mahmut (Elsevier, 2021/15/09)DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ...