Patients' concerns regarding biological agents in rheumatology
dc.contributor.author | Pehlivan, Yavuz | |
dc.contributor.author | Orucoglu, Nurdan | |
dc.contributor.author | Pehlivan, Seda | |
dc.contributor.author | Kimyon, Gezmis | |
dc.contributor.author | Zengin, Orhan | |
dc.contributor.author | Kucuk, Adem | |
dc.contributor.author | Sahin, Ali | |
dc.contributor.author | Tomas, Nazmiye | |
dc.contributor.author | Oksuz, Mustafa Ferhat | |
dc.contributor.author | Kisacik, Bunyamin | |
dc.contributor.author | Akar, Servet | |
dc.contributor.author | Onat, Ahmet Mesut | |
dc.contributor.author | Dalkilic, Ediz | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:38:08Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:38:08Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1756-1841 | |
dc.identifier.issn | 1756-185X | |
dc.identifier.uri | https://dx.doi.org/10.1111/1756-185X.13319 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/6270 | |
dc.description | WOS: 000434417500008 | en_US |
dc.description | PubMed ID: 29879318 | en_US |
dc.description.abstract | ObjectiveThe potential side effects of biological agents may increase the anxiety levels of patients and influence not only their desire to use these therapies but also their concordance to treatment. This study aimed to determine the level and prevalence of drug-related concern in patients treated with biological agents and to acquire additional information regarding the related causes. Materials and MethodsA total of 1134 patients who were using biological agents for at least 3months with a diagnosis of rheumatic diseases were enrolled. General anxiety levels were evaluated using the State-Trait Anxiety Inventory (STAI). ResultsThe most common cause for drug-related concerns was the potential side effects of the drugs (59.5%). Among the potential side effects, cancer risk was the most common cause for concern (40.1%), followed by the risk of tuberculosis activation (30.7%). Anxiety levels were higher in patients who experienced side effects than in other patients, and this difference was statistically significant (P<0.05). STAI trait and state scores were moderately correlated with anxiety levels related to the drug (P<0.001). ConclusionAnxiety related to biological agents may significantly affect the patients' anxiety levels. Awareness regarding the patients' concerns and expectations related to the drug is important to ensure drug adherence and concordance to treatment. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | WILEY | en_US |
dc.relation.isversionof | 10.1111/1756-185X.13319 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | biological agents | en_US |
dc.subject | patient | en_US |
dc.subject | patients' concern | en_US |
dc.subject | rheumatology | en_US |
dc.title | Patients' concerns regarding biological agents in rheumatology | en_US |
dc.type | article | en_US |
dc.relation.journal | INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES | en_US |
dc.contributor.department | [Pehlivan, Yavuz -- Orucoglu, Nurdan -- Oksuz, Mustafa Ferhat -- Dalkilic, Ediz] Uludag Univ, Dept Rheumatol, Sch Med, Bursa, Turkey -- [Pehlivan, Seda] Uludag Univ, Hlth Sci Fac, Dept Nursing, Bursa, Turkey -- [Kimyon, Gezmis -- Zengin, Orhan -- Kisacik, Bunyamin -- Onat, Ahmet Mesut] Gaziantep Univ, Sch Med, Dept Rheumatol, Gaziantep, Turkey -- [Kucuk, Adem] Necmettin Erbakan Univ, Meram Sch Med, Dept Rheumatol, Konya, Turkey -- [Sahin, Ali] Cumhuriyet Univ, Dept Rheumatol, Sch Med, Sivas, Turkey -- [Tomas, Nazmiye -- Akar, Servet] Izmir Katip Celebi Univ, Sch Med, Dept Rheumatol, Izmir, Turkey | en_US |
dc.contributor.authorID | Pehlivan, Seda -- 0000-0002-1670-0672; Orucoglu, Nurdan -- 0000-0002-8613-5373 | en_US |
dc.identifier.volume | 21 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.endpage | 1226 | en_US |
dc.identifier.startpage | 1219 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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