Browsing Sivas Teknik Bilimler Meslek Yüksekokulu Makale Koleksiyonu by Author "10d4dac2-7547-4b68-a31b-4d6a4d12c03a"
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Cytotoxic effect, spectroscopy, DFT, enzyme inhibition, and moleculer docking studies of some novel mesitylaminopropanols: Antidiabetic and anticholinergics and anticancer potentials
Tüzün, Burak; Çakmak, Neşe Keklikçioğlu; Tunçbilek, Zuhal; Taş, Ayhan; Taslimi, Parham; Khalilov, Ali N. (09 October)b-Amino alcohols (2–4) used in this study were re-synthesized in accordance with our previous study. All compounds were characterized by the combination of NMR, UV–Vis, IR experimental and theoretical spectral data. Then, ... -
Efficient synthesis and molecular docking studies of new pyrimidine-chromeno hybrid derivatives as potential antiproliferative agents
Yavuz, Sevtap Çağlar; Akkoç, Senem; Tüzün, Burak; Şahin, Onur; Saripinar, Emin (26 May 202)Various novel heterocyclic compounds containing pyrimidine nuclei 5H-chromeno[4,3-d]pyrimidine (4a–c, e–h, l–r, t) and pyrimidine-5-yl-(2- hydroxyphenyl)methanone (5a, c, d, f–k, m–o, r, s, u) were synthesized from the ... -
Investigation of structural, electronical and in vitro cytotoxic activity properties of some heterocyclic compounds
Akkoç, Senem; Tüzün, Burak; Özalp, Ayhan; Kökbudak, Zülbiye (19 July 20)A series of heterocyclic compounds ( 15 ) were synthesized, characterized and tested towards two human cancer cell lines for learning their in vitro antiproliferative activities. Compound 3 demonstrated the most promising ... -
Structurally diverse heterobimetallic Pb(II)-Salen complexes mechanistic notion of cytotoxic activity against neuroblastoma cancer cell: Synthesis, characterization, protein–ligand interaction profiler, and intuitions from DFT
Majumdar, Dhrubajyoti; Tüzün, Burak; Pal, Tapan Kumar; Saini, Reena V; Bankura, Kalipada; Mishra, Dipankar (24 Septemb)In this work, two new heterobimetallic Pb(II) complexes, namely [Zn(L1)(η1-NCS)Pb(η1-SCN)] (1) and [Cd(L2) (η1-NCS)Pb(η1-SCN)]n (2) integrated from Salen ligands (L1/L2) in the presence of NaSCN. The title compounds were ... -
Synthesis of (4R)-2-(3-hydroxyphenyl)thiazolidine- 4-carboxylic acid substituted phthalocyanines: Anticancer activity on different cancer cell lines and molecular docking studies
Bilgiçli, Ahmet T.; Bilgicli, Hayriye Genc; Hepokur, Ceylan; Günsel, Armağan; Zengin, Mustafa; Yarasir, M. Nilüfer; Tüzün, Burak (9 March 20)In this study, firstly, (4R)-2-(3-hydroxyphenyl)thiazolidine-4-carboxylic acid (1) and (4R)-2-(3-(3,4-dicyanophenoxy)phenyl)thiazolidine-4-carboxylic acid (2) were prepared. Then, the novel type metallophthalocyanines ... -
Tetra-substituted phthalocyanines bearing thiazolidine derivatives: synthesis, anticancer activity on different cancer cell lines, and molecular docking studies
M. Nilüfer Yarasir; Bilgiçli, Ahmet T.; Hepokur, Ceylan; Bilgicli, Hayriye Genc; Tüzün, Burak; Günsel, Armağan; Mısır, Sema; Zengin, Mustafa; Yarasir, M. Nilüfer (5th Octobe)In the first step, (4R)-2-(2-hydroxyphenyl)thiazolidine-4-carboxylic acid (c) and 2-(2-(3,4-dicyanophenoxy) phenyl)thiazolidine-4-carboxylic acid (1) were prepared. Then, the peripherally tetra-substituted metallophthalocyanines ...