Primary central nervous system lymphoma in daily practice and the role of autologous stem cell transplantation in relapsed disease: A retrospective multicenter study
Date
2016Author
Erkurt, Mehmet AliBerber, Ilhami
Tekgunduz, Emre
Dogu, Mehmet Hilmi
Korkmaz, Serdal
Demir, Cengiz
Yilmaz, Mehmet
Akay, Olga Meltem
Pala, Cigdem
Bilen, Yusuf
Kaya, Emin
Sari, Ismail
Sencan, Mehmet
Kuku, Irfan
Altuntas, Fevzi
Dal, Mehmet Sinan
Aydogdu, Ismet
Metadata
Show full item recordAbstract
We investigated the course of 54 patients presenting with primary central nervous system lymphoma, who were treated in daily practice. The patients were treated with chemotherapy and/or radiotherapy and/or intrathecal chemotherapy. At a median follow-up period of 23 months (range 1-71), median relapse-free survival (RFS) and overall survival (OS) were not reached. Estimated 2-year RFS and OS rates were 42% and 48%, respectively. Ten relapsed PCNSL patients underwent ASCT. Complete remission rate of these patients was 40%, with 20% treatment-related mortality. Estimated 2-year RFS and OS rates were 37% and 40%, respectively. The prognosis of patients with PCNSL, who received off-study treatment, is still dismal. (c) 2016 Elsevier Ltd. All rights reserved.
Source
TRANSFUSION AND APHERESIS SCIENCEVolume
54Issue
1Collections
- Makale Koleksiyonu [5200]
- Makale Koleksiyonu [5745]
- Öksüz Yayınlar Koleksiyonu - WoS [6162]
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