dc.contributor.author | Karakus, Savas | |
dc.contributor.author | Yildiz, Caglar | |
dc.contributor.author | Akkar, Ozlem | |
dc.contributor.author | Sancakdar, Enver | |
dc.contributor.author | Ulger, Dilara | |
dc.contributor.author | Cetin, Ali | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:46:40Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:46:40Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1940-5901 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7558 | |
dc.description | WOS: 000379157300063 | en_US |
dc.description.abstract | Objective: The aim of this study is to assess the diagnostic value of the neutrophil-to-lymphocyte ratio in the differential diagnosis of patients with vaginal bleeding related to ectopic pregnancy or miscarriage. Study design. A retrospective analysis of case histories of patients with documented ectopic pregnancies or miscarriages diagnosed by a combination of clinical examination, transvaginal ultrasonography, and human chorionic gonadotropin assay. Normal pregnant women were used as controls. The neutrophil-to-lymphocyte ratio was calculated in the patients and controls. Results: The neutrophil-to-lymphocyte ratio was higher in patients with ectopic pregnancies than in patients with normal pregnancies or patients with miscarriages (P<0.05). Although the neutrophil-to-lymphocyte ratio in patients with miscarriages was higher than that in patients with normal pregnancies, the difference was not statistically significant. For ectopic pregnancy, using 3.0 as a cutoff value, the sensitivity and specificity of the neutrophil-to-lymphocyte ratio were 61%. For miscarriage, using 2.8 as a cutoff value, the sensitivity and specificity of neutrophil-to-lymphocyte ratio were 53%. Conclusions: In patients with vaginal bleeding related to ectopic pregnancy or miscarriage, an increased neutrophil-to-lymphocyte ratio in the absence of infection may be used as an early diagnostic marker for ectopic pregnancy. Miscarriage did not result in a significant increase in the neutrophil-to-lymphocyte ratio. Further studies performed in patients grouped by gestational age and rupture status are needed to determine the diagnostic value of the neutrophil-to-lymphocyte ratio in patients suspected of an ectopic pregnancy. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | E-CENTURY PUBLISHING CORP | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Ectopic pregnancy | en_US |
dc.subject | miscarriage | en_US |
dc.subject | neutrophil-to-lymphocyte ratio | en_US |
dc.title | The significance of the neutrophil-to-lymphocyte ratio in differantial diagnosis of ectopic pregnancy and miscarriage | en_US |
dc.type | article | en_US |
dc.relation.journal | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | en_US |
dc.contributor.department | [Karakus, Savas -- Yildiz, Caglar -- Akkar, Ozlem -- Cetin, Ali] Cumhuriyet Univ, Sch Med, Dept Obstet & Gynecol, TR-58140 Sivas, Turkey -- [Sancakdar, Enver -- Ulger, Dilara] Cumhuriyet Univ, Sch Med, Dept Biochem, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | Cetin, Ali -- 0000-0002-5767-7894 | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.endpage | 11333 | en_US |
dc.identifier.startpage | 11327 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |