dc.contributor.author | Erdem, A. | |
dc.contributor.author | Dogan, O. T. | |
dc.contributor.author | Yontar, O. C. | |
dc.contributor.author | Epozturk, K. | |
dc.contributor.author | Ozlu, M. F. | |
dc.contributor.author | Ozturk, S. | |
dc.contributor.author | Ayhan, S. S. | |
dc.contributor.author | Erdem, F. H. | |
dc.contributor.author | Yazici, M. | |
dc.contributor.author | Akkurt, I. | |
dc.contributor.author | Talay, F. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:58:51Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:58:51Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 1128-3602 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/8564 | |
dc.description | WOS: 000326602700012 | en_US |
dc.description | PubMed ID: 24174360 | en_US |
dc.description.abstract | OBJECTIVES: To demonstrate the pure effect of obstructive sleep apnea syndrome (OSAS) on cardiac autonomic function (CAF) using heart rate turbulence (HRT) parameters. PATIENTS AND METHODS: A total of 64 patients with OSAS and 30 age-and gender-matched healthy subjects were enrolled. All subjects had normal coronary arteries and were free from diabetes mellitus (DM) and hypertension (HT). The HRT parameters (TO, turbulence onset; TS, turbulence slope) were obtained from 24-h ambulatory electrocardiogram (ECG) recordings. HRT parameters were compared between groups, and the relationship between HRT and the apneahypopnea index (AHI) was examined. RESULTS: No between-group differences were found in age or gender. Mean TO was significantly higher in the OSAS group than in healthy controls (0.89 +/- 0.5, -0.08 +/- 0.26; p < 0.001; respectively). The mean TS did not differ between the two groups (2.81 +/- 3.06 versus 3.14 +/- 2.33; p = 0.212). The AHI was positively correlated with TO (r = 0.845, p < 0.001). The multiple logistic regression analysis revealed that after adjustment for other variables, TO was a significant and independent predictor of AHI, OR 2.394 (95% CI: 1.596-3.591). CONCLUSIONS: HRT (TO in particular) is correlated with AHI. Thus, impaired HRT may be an important factor underlying the occurrence of arrhythmia and sudden cardiac death in patients with OSAS. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | VERDUCI PUBLISHER | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Obstructive sleep apnea syndrome | en_US |
dc.subject | Cardiac autonomic function | en_US |
dc.subject | arrhythmia | en_US |
dc.subject | ambulatory ECG | en_US |
dc.subject | turbulence onset | en_US |
dc.subject | turbulence slope | en_US |
dc.title | The pure effects of obstructive sleep apnea syndrome on cardiac autonomic functions: heart rate turbulence analysis | en_US |
dc.type | article | en_US |
dc.relation.journal | EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | en_US |
dc.contributor.department | [Erdem, A. -- Ozlu, M. F. -- Ozturk, S. -- Ayhan, S. S. -- Yazici, M.] Abant Izzet Baysal Univ, Fac Med, Dept Cardiol, Bolu, Turkey -- [Dogan, O. T. -- Epozturk, K. -- Akkurt, I.] Cumhuriyet Univ, Fac Med, Dept Chest Dis, Sivas, Turkey -- [Yontar, O. C. -- Erdem, F. H.] Numune Hosp, Dept Cardiol, Sivas, Turkey -- [Talay, F.] Abant Izzet Baysal Univ, Fac Med, Dept Chest Dis, Bolu, Turkey | en_US |
dc.contributor.authorID | Yontar, Osman Can -- 0000-0002-0099-8654 | en_US |
dc.identifier.volume | 17 | en_US |
dc.identifier.issue | 20 | en_US |
dc.identifier.endpage | 2783 | en_US |
dc.identifier.startpage | 2778 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |