dc.contributor.author | Erselcan, Taner | |
dc.contributor.author | Egilmez, Hulusi | |
dc.contributor.author | Hasbek, Zekiye | |
dc.contributor.author | Tandogan, Izzet | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:04:03Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:04:03Z | |
dc.date.issued | 2012 | |
dc.identifier.issn | 0284-1851 | |
dc.identifier.uri | https://dx.doi.org/10.1258/ar.2011.110412 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/9226 | |
dc.description | WOS: 000301403100018 | en_US |
dc.description | PubMed ID: 22139722 | en_US |
dc.description.abstract | Background: Without appropriate control measures, contrast-induced nephropathy (CIN) incidence has been claimed to be overestimated. Purpose: To evaluate the relationship and the difference between differential serum creatinine (DsCr), which is currently surrogating as a marker of GIN, and measured differential GFR values as a control measure (DGFR) in hospitalized patients. Material and Methods: GFR was measured two times by Tc-99m DTPA, before and 48 h after contrast media (CM), along with sCr and BUN in 35 inpatients (22 men, 13 women, mean age +/- SD = 61 +/- 14) with no known chronic kidney disease. Results: Relationship was moderate between GFR and sCr (R = 0.50, P < 0.01) in the study population. Pre-CM vs. post-CM values of GFR, sCr and BUN were not statistically different as (mean +/- SD); 78 +/- 36 vs. 73 +/- 35 mL/min/1.73m(2), 0.95 +/- 0.26 vs. 0.94 +/- 0.26 mg/dl and 21 +/- 16 vs. 19 +/- 13 mg/dl, respectively, in the study group. According to basal GFR values, 14 patients (40%) seemed carrying risk of GIN (GFR < 60 mymin/1.73m2) in whom only two had sCr >1.5 mg/dl. Twenty-five patients (71%) had discordant results in relation to Ds Cr and DGFR and two of them had GIN according to classical definition of Ds Cr, although having basal sCr <1.1 mg/dl. Yet, both had low, but stable GFR values. None of patient from the study group underwent hemodialysis. Conclusion: Significant discordance was observed between differential serum creatinine and measured differential GFR in hospitalized patients, suggesting that GIN incidence calculations only based on hospital registry may carry risk of error. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | ROYAL SOC MEDICINE PRESS LTD | en_US |
dc.relation.isversionof | 10.1258/ar.2011.110412 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Contrast agents | en_US |
dc.subject | screening | en_US |
dc.subject | radionuclides | en_US |
dc.subject | toxicity | en_US |
dc.subject | renal failure | en_US |
dc.title | Contrast-induced nephropathy: controlled study by differential GFR measurement in hospitalized patients | en_US |
dc.type | article | en_US |
dc.relation.journal | ACTA RADIOLOGICA | en_US |
dc.contributor.department | [Erselcan, Taner -- Hasbek, Zekiye] Cumhuriyet Univ, Sch Med, Dept Nucl Med, Sivas, Turkey -- [Egilmez, Hulusi] Cumhuriyet Univ, Sch Med, Dept Radiol, Sivas, Turkey -- [Tandogan, Izzet] Cumhuriyet Univ, Sch Med, Dept Cardiol, Sivas, Turkey | en_US |
dc.identifier.volume | 53 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.endpage | 232 | en_US |
dc.identifier.startpage | 228 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |