Cerebral Venous Sinus Thrombosis Presenting as Transient Ischemic Attacks in a Case With Homozygous Mutations of MTHFR A1298C and CG677T
Tarih
2012Yazar
Yildiz, Ozlem KayimCevik, Seyda
Cil, Gulsum
Oztoprak, Ibrahim
Bolayir, Ertugrul
Topaktas, Suat
Üst veri
Tüm öğe kaydını gösterÖzet
We report a case with recurrent, transient attacks of slurred speech, weakness, and numbness of the right half of the face and the right arm without seizure activity, accompanied by headache and double vision. Neurologic examination revealed bilateral papilledema and right abducens palsy. Brain magnetic resonance imaging revealed thrombosis of the dural venous sinuses and the cortical veins, with no evidence of parenchymal lesion. Homozygous mutations were found for methylenetetrahydrofolate reductase (MTHFR) A1298C and MTHFR CG677T. Anticoagulation with heparin and warfarin resulted in prompt cessation of the transient attacks, as well as the signs and symptoms of increased intracranial pressure. This report documents that, although rare, transient ischemic attacks can result from cerebral venous thrombosis.
Kaynak
JOURNAL OF STROKE & CEREBROVASCULAR DISEASESCilt
21Sayı
1Bağlantı
https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2010.03.010https://hdl.handle.net/20.500.12418/9369
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