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    Clinico-pathological characteristics in young and elderly patients with lung cancer
    (2011) Arslan, Sulhattin; Özşahin, Sefa Levent; Akkurt, Ibrahim
    Introduction: The aim of the present study was to determine the differences between the clinico-pathological characteristics of lung cancers among elder and young patients Materials and Method: 160 patients with lung cancer were included in the study retrospectively. Age, gender, diagnostic methods, performances, accompanying diseases and histological types of the cancer of patients were all investigated. Patients were divided into two groups; the younger group, under 65 years of age and the elderly group, over 65 years of age. Both groups were compared according to the clinico-pathological features. Results: There were 124 patients (13 female, 111 male) in the younger group, 36 patients (3 female, 33 male) in the elderly group. Medical comorbidity was significantly higher (p=0.045) in the elderly group. Coughing- expectoration rate was statistically higher (p=0.014) in the younger group. Hemoptysis was signiŞcantly higher (p=0.018) in the elderly group. Poor performances were significantly higher (p=0.008) in the elderly group. Adenocarcinoma of the lung was more frequent (p=.0.037) among the younger group whereas squamous cell cancer incidence was higher (p=0.049) in the elderly group. Conclusion: While coughing-expectoration symptoms and the lung adenocarcinoma were significantly higher in the younger group, hemoptysis, medical comorbidity, poor performance and the squamous cell carcinoma were sigcantly more frequent in the elderly group.
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    Venous thromboembolism risk in patients with lung cancer
    (2010) Arslan, Sulhattin; Karadayi, Şule; Özşahin, Sefa Levent; Şahin, Ekber; Akkurt, Ibrahim
    Background: The incidence of venous thromboembolism in lung cancer patients was investigated and the relationships between venous thromboembolism and histopathological types, stage, and treatment of the cancer, as well as accompanying chronic diseases were evaluated. Methods: This retrospective study was based on the evaluation of the files of 137 lung cancer patients (126 males, 11 females; mean age 58±28 years; range 24 to 78 years), who were diagnosed and treated in our clinic between January 2006 and May 2009. The diagnosis of venous thromboembolism was based on the clinical findings and the findings of the thorax computed tomography-angiography, ventilationperfusion scintigraphy, and Doppler ultrasound. The name of the thrombosed vein was recorded. Results: Venous thromboembolism was determined in 8.8% patients. Of 121 smokers, 9.1% had venous thromboembolism. Other diseases were present in 44.6% of patients. Some patients had more than one accompanying disease (chronic obstructive lung disease, arterial hypertension, coronary artery disease, diabetes mellitus, congestive heart failure). The incidence rate of accompanying diseases in the patients with venous thromboembolism was 58.3%. Of the patients, 22.6% had small cell lung cancer, while 77.4% had non-small cell lung cancer. Venous thromboembolism was present in 6.4% of the patients with small cell lung cancer, and in 9.4% of the patients with nonsmall cell lung cancer. Histopathologically, adenocarcinoma was detected in 50% of the patients with venous thromboembolism. The cancer in 58.3% of the patients with venous thromboembolism was in its advanced stage, and the cancer in 58.3% of the patients developed venous thromboembolism during first step treatment. Metastasis was noted in 53.8% of patients. Conclusion: Although the differences were not statistically significant, the incidence rate of venous thromboemboli was higher in the group of patients with adenocarcinoma, advanced stage cancer, metastasis, and chronic comorbidity. It is also slightly higher in patients who were administered chemotherapy.