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    EARLY EXPERIENCES WITH ENDOSCOPIC ENDONASAL TRANSSPHENOIDAL SURGERY
    (2020) Söylemez, Burçak; Durmuş, Kasım; Bora, Adem; Eğilmez, Hatice Reyhan; Özum, Ünal
    Objective: Pituitary tumors (PT) constitute 10-15% of intracranial tumors, and 90% of surgically treated PTs are pituitary adenoma (PA). PA can be treated using pharmacologic, surgical, and radiotherapeutic methods. Today, endoscopic endonasal transsphenoidal surgery (EETS) is more commonly performed because it is less invasive, provides a panoramic image, enables better evaluation of anatomic structures and adjacencies, and reduces hospital length of stay compared to other surgical methods. In this study, we evaluated the results of 21 patients who underwent EETS in our clinic. Methods: A total of 21 patients who underwent EETS between 2016 and 2020 in our clinic were evaluated retrospectively. Thirteen(61.90%) of the patients were women, 8 (38.09%) were men, and the mean age was 53.71 (24-73) years. Results: Pathology reports indicated pituitary adenoma in 17 patients, Rathke's cleft cyst in 3 patients, and hypophysitis in 1 patient. Rhinorrhea occurred in 3 patients, transient diabetes insipidus (DI) in 1 patient, and hypopituitarism in 2 patients. Two of the patients died. Conclusion: The acquisition of endoscopic experience involves a learning curve in which there is initially a temporary high incidence of perioperative complications. Compared with the literature, our results are consistent with the beginning of the learning curve.
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    Management of Neural Tube Defect: A Single-Center Experience
    (2021) Söylemez, Burçak; Bulut, Zekeriya; Koç, Fatih; Özum, Ünal; Karadağ, Özen
    Objective: Neural tube defects are a heterogeneous and complex group of congenital central nervous system anomalies involving that involve the failed closure of the vertebral column. The spinal cord is frequently affected, and neural tube defects substantially increase the risk of disability and death within the first year of life. Neural malformations are often associated with abnormalities in other organ systems. This study presents our clinical experiences regarding the development and comorbidities of infants with neural tube defect and compares them with the literature.Materials and Methods: This retrospective study included 47 patients (24 females, 23 males) who underwent surgical treatment for neural tube defect in the neurosurgery department of Sivas Cumhuriyet University Faculty of Medicine Training and Research Hospital between 2000 and 2020.Results: Of the 47 patients, 34 (72.34%) had myelomeningocele and 13 (27.65%) had meningocele. Lesion location was thoracolumbar in 38 patients (80.85%), lumbar in 5 (10.63%), lumbosacral in 3 (6.38%), and cervical in 1 patient (2.12%). Twenty-seven patients (57.44%) underwent ventriculoperitoneal shunting due to hydrocephalus. Thirty patients (63.82%) had Chiari malformation type II, 13 (27.65%) had cranial anomalies, and 1 (2.12%) had Down syndrome. In 9 patients, the conus medullaris terminated at or below the L3 vertebral body (19.14%). Two patients (4.25%) died.Conclusion: Because of their multidimensional nature, neural tube defects have various effects on individuals, families, society, and the field of medicine. This study represents a small group of patients with neural tube defects. Cases should be included from other centers to compile more comprehensive data about patients with neural tube defects in Turkey.