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Öğe Evaluation of sleep quality in rheumatoid arthritis patients(Bayrakol Medical Publisher, 2024) Tuncay, Mehmet Siddik; Sahin, Ozlem; Semiz, Murat; Semiz, Esra; Alim, Bulent; Peksen, Halil; Salihoglu, SalihAim: The purpose of this study was to evaluate treatment effects on sleep quality and fatigue in patients with RA. Besides, we aim to examine possible effects of disease activity, pain and socio-demographic features on sleep quality and fatigue. Material and Methods: In this study, 78 patients diagnosed with RA according to the American Rheumatism Association (ACR) 1987 revised criteria and European League Against Rheumatism (EULAR) criteria were compared with a parallel healthy control group (n=48). All participants were given a sociodemographic questionnaire, the Pittsburgh Sleep Quality Index (PSQI), Multidimensional Assessment of Fatigue Scale (MAF), Visual Analog Scale (VAS), Disease Activity Score 28 (DAS28). Results: The mean duration of diagnosis was 9.10 +/- 8.54 years and the mean score of DAS28 was 3.25 +/- 1.04 in patients with RA. In terms of total PSQI, the differences between two groups were found statistically significant (p=0.001; t=8.023). In terms of MAF, The differences between two groups were found statistically significant (p=0.001; t=3.668). The sleep disturbance and daytime functioning scores were found as 1.86 +/- 0.69, 1.40 +/- 0.83 respectively in nonbiological DMARD group and 1.54 +/- 0.66; 0.84 +/- 0.93 in biological + non -biological DMARD group. There were statistically significant differences between groups (p=0.043; t=2.054, p=0.008; t=2.730). According to correlation analysis between DAS28 and disease duration, a positive correlation has been found (r = 0.297; p = 0.008). Discussion: Patients with RA generally experience more fatigue and have worse sleep quality than healthy individuals. High disease activity can lead to longer sleep latency, reduced daytime functionality, and increased fatigue symptoms.Öğe Serum cortisol and dehydroepiandrosterone-sulfate levels after balneotherapy and physical therapy in patients with fibromyalgia(SAUDI MED J, 2016) Semiz, Esra A.; Hizmetli, Sami; Semiz, Murat; Karadag, Ahmet; Adali, Merve; Tuncay, Mehmet S.; Alim, Bulent; Hayta, Emrullah; Uslu, Ali U.Objectives: To investigated serum cortisol and serum dehydroepiandrosterone-sulphate (DHEA-S) levels between fibromyalgia (FMS) patients and a control group, and the effect of balneotherapy (BT) on these hormones. Methods: Seventy-two patients with FMS and 39 healthy volunteers were included in the study. This prospective and cross-sectional study was carried out in the Medical Faculty, Physical Medicine and Rehabilitation Clinic, Cumhuriyet University, Cumhuriyet, Turkey between June 2012 and June 2013. Patients were divided into 2 groups. There were 40 patients in the first group, consisting of BT and physical therapy (PT) administered patients. There were 32 FMS patients in the second group who were only administered PT. Thirty-nine healthy volunteers were enrolled as a control group. Result: Cortisol was observed to be lower in FMS patients compared with the controls (10.10 +/- 4.08 mu g/dL and 11.78 +/- 3.6 mu g/dL; p= 0.033). Serum DHEA-S level was observed to be lower in FMS patients compared with the controls (89.93 +/- 53.96 mu g/dL and 143.15 +/- 107.92 mu g/dL; p= 0.015). Average serum cortisol levels of patients receiving BT were determined to be 9.95 +/- 3.20 mu g/dL before treatment and 9.06 +/- 3.77 mu g/dL after treatment; while average serum DHEA-S levels were 77.60 +/- 48.05 mu g/dL before treatment, and 76.84 +/- 48.71 mu g/dL after treatment. No significant changes were determined in serum cortisol and DHEA-S levels when measured again after BT and PT. Conclusion: Low levels of serum cortisol and DHEA-S were suggested to be associated with the physiopathology of FMS.Öğe Unexpected Complication Associated with Balneotherapy: Skin and Soft Tissue Infection(AMER INST PHYSICS, 2017) Alim, Bulent; Bostanci, Fahrettin; Servi, M. Alperen; Cetinel, Sinan; Bingol, M. Ozan; Akdemir, AO; Ekinci, A; Han, I; Set, E; Dadasoglu, F; Karagoz, K; Oztekin, ABalneotherapy cure is an ongoing process, but patients can benefit most when cure is complete. For these reason, patients should be closely monitored and necessary precautions should be taken in terms of the complications that may occur in order to prevent the interruption or discontinuation of balneotherapy. Here, we wanted to represent a case that developed left leg soft tissue infection during the application of balneotherapy and because of this reason we stopped the balneotherapy As a result, when balneotherapy is planned for patients with risk factors such as diabetes and obesity, frequent examination of the skin and the application of skin moisturizers will be beneficial to prevent itching and skin dryness.