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Öğe Cervicomediastinal cystic hygroma: Case report(2010) Manduz, Şinasi; Altuntaş, Emine Elif; Katrancio?lu, Nurkay; Karahan, O?uz; Erçöçen, Ali RizaLymphangioma is a rare benign tumor seen in first decad of the life. Cystic hygroma (CH) is a congenital abnormality of the lymphatic vessels, with an incidence of 1/6000. CH especially is located in the posterior cervical triangle (75%) head and neck region also that is located in the axilla, chest wall, shoulder, mediastinium, anterior wall of the abdomen, or inguinal region. Most of the cases are diagnosed at birth and cysts continue to expand slowly. The main pathology of the CH connections of the jugulary vein and lymphatic vesels are not consisting. The differential diagnosis CH includes lipoma, hemangioma, branchial cleft cyst, thyroglossal cyst, dermoid cyst, thimic cyst, laryngosel, thyroid mass, neuroblastoma, rhabdomysarcoma, lymphadenopathy meningoencephalocele and encephalocele. Treatment of this pathology is total excision but the lesions recurs in 10-25% of patients. The recurrence ratio changes by histologicaly type and localization of the lesion the. Another treatment alternative of the CH is intra lesional injection of the sclerosine material, steroid or bleomicine. In this study a 10 months-old-male infant who had cervicomediastinal cystic hygroma is presented in the high light of literature. Copyright © 2010 by Türkiye Klinikleri.Öğe Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?(PLA General Hospital Department of Otolaryngology Head and Neck Surgery, 2018) Doğan, Mehtap; Durmuş, Kasım; Hasbek, Zekiye; Altuntaş, Emine ElifObjective: The objective of this study was to examine the effect of hypothyroidism on hearing function in patients surgically treated for differentiated thyroid cancer and subsequently experienced hypothyroidism during preparation for follow up I-131 scintigraphy scan by either recombinant human thyroid stimulating hormone (rhTSH) treatment or thyroid hormone withdrawal (THW). Methods: A total of 55 patients undergoing I-131 scintigraphy scan following surgeries for differentiated thyroid cancer were included in the study, including 25 patients prepared by administration of recombinant TSH (rhTSH Group) and 30 patients by thyroid hormone withdrawal (THW Group). Results: Air conduction thresholds at 1, 2 and 4 kHz for both ears were higher during hypothyroid period than during euthyroid period for patients in the THW group (p < 0.05) but not for patients in the rhTSH group. Conclusion: Sensorineural hearing loss was detected, especially at low frequencies, in patients with DTC after surgical treatment whose hormone replacement therapy was withdrawn but not in those receiving rhTSH. It is therefore preferred to use rhTSH when preparing for I-131 scintigraphy scan in patients at risk for hearing loss. © 2018 PLA General Hospital Department of Otolaryngology Head and Neck SurgeryÖğe Effects of the Lunar Cycle, Seasons and the Meteorological Factors on Peripheral Vertigo(2022) Koparal, Mehtap; Altuntaş, Emine Elif; Yılmazer, Cüneyt; Altunışık, Erman; Karataş, MehmetObjective: This study aimed to determine whether peripheral vertigo is related to the lunar cycle, the seasons, or meteorological factors, in patients who presented to the ear, nose, and throat clinic. Methods: All the patients, diagnosed with vertigo between January 2020 and January 2022, were identified through a retrospective review of our hospital database. The clinical and demographic data of the patients were recorded. Daily humidity (minimum, average, and maximum; %), daily temperature (minimum, average, and maximum; °C), daily average and maximum wind speed (m/min), daily air pressure (minimum and average maximum; hPa) and wind direction (degrees) values were noted. Also, the phases of the moon, i.e., first quarter, new moon, last quarter, and full moon periods were determined. Results: A total of 5,432 patients were included in the study. No statistically significant differences were noted among them with respect to the lunar cycle (p=0.233). However, patient density was found to increase in the winter months. Conclusion: This study concluded that the frequency of diseases is related to meteorological factors, nonetheless, no statistical relationship was found between the lunar cycle and the frequency of patient entries.Öğe Genetic constitution analysis of idiopathic sudden hearing loss(İstanbul Üniversitesi, 2010) Bora, Adem; Altuntaş, Emine Elif; Özdemir, Öztürk; Uysal, İsmail Önder; Müderris, SuphiObjectives: The purpose of this research is to understand the etiology of sudden hearing loss due to genetic factors in Turkish people. Determination of these genetic factors and better understanding of molecular pathogenesis may guide more realistic planning and treatment recommendations. Patients and Methods: Forty patients Group 1; 19 males, 21 females; mean age 37.9±15.6 years; range 9 to 76 years who presented with sudden hearing loss to the Ear, Nose and Throat Clinic of Medical Faculty Hospital of Cumhuriyet University between January 2008 and June 2009, and were diagnosed with sudden hearing loss through history, physical examination and review of audiometric findings, and 20 healthy volunteers Group 2; 14 males, 6 females; mean age 31.7±4.4 years; range 24 to 43 years for the control group were included in this study. All Patients were evaluated by the genetic clinic for the GJB2, GJB3, GJB6 and WFS1 gene using multiplex ligation-dependent probe amplification MLPA method mutation analysis. Results: No difference was found in the peripheral blood sample analyses of the two groups at WFS1 exon 8 and connexin 26, 30 and 31 gene zones using the MLPA method with respect to heterozygous mutation p=0.291, p>0.05 . In four patients in group 1 heterozygous mutation was detected at the target gene zone. Heterozygous mutation was in the WFS1 exon 8 zone in two patients; and in the WFS1 exon 1 zone in other two patients. Conclusion: Sudden hearing loss studies in the future should include connexin 26, connexin 30 and other gene mutations that may affect the function of the gap-junction located in the region of the cochlea stria vascularis stV , basal membrane BM , spiral limbus Li and spiral ligament SL . These studies should be performed on larger series, and should include family members of patients with sudden hearing loss.Öğe [Genetic constitution analysis of idiopathic sudden hearing loss].(2010) Bora, Adem; Altuntaş, Emine Elif; Ozdemir, Oztürk; Uysal, Ismail Onder; Müderris, SuphiThe purpose of this research is to understand the etiology of sudden hearing loss due to genetic factors in Turkish people. Determination of these genetic factors and better understanding of molecular pathogenesis may guide more realistic planning and treatment recommendations. Forty patients (Group 1; 19 males, 21 females; mean age 37.9+/-15.6 years; range 9 to 76 years) who presented with sudden hearing loss to the Ear, Nose and Throat Clinic of Medical Faculty Hospital of Cumhuriyet University between January 2008 and June 2009, and were diagnosed with sudden hearing loss through history, physical examination and review of audiometric findings, and 20 healthy volunteers (Group 2; 14 males, 6 females; mean age 31.7+/-4.4 years; range 24 to 43 years) for the control group were included in this study. All Patients were evaluated by the genetic clinic for the GJB2, GJB3, GJB6 and WFS1 gene using multiplex ligation-dependent probe amplification (MLPA) method mutation analysis. No difference was found in the peripheral blood sample analyses of the two groups at WFS1 exon 8 and connexin 26, 30 and 31 gene zones using the MLPA method with respect to heterozygous mutation (p=0.291, p>0.05). In four patients in group 1 heterozygous mutation was detected at the target gene zone. Heterozygous mutation was in the WFS1 exon 8 zone in two patients; and in the WFS1 exon 1 zone in other two patients. Sudden hearing loss studies in the future should include connexin 26, connexin 30 and other gene mutations that may affect the function of the gap-junction located in the region of the cochlea stria vascularis (stV), basal membrane (BM), spiral limbus (Li) and spiral ligament (SL). These studies should be performed on larger series, and should include family members of patients with sudden hearing loss.Öğe KULAK BURUN BOĞAZ ALERJİSİ HASTALIKLARI ALANINDA NE DURUMDAYIZ?(2020) Topuz, Bülent; Kara, Cüneyt Orhan; Çanakçıoğlu, Salih; Günhan, Kıvanç; Coşkun, Berna Uslu; Keleş, Erol; Altuntaş, Emine ElifAmaç; Alerjik hastalıklar Kulak Burun Boğaz ve Baş Boyun Cerrahisi Uzmanlık eğitiminin en önemli başlıklarından birisidir. KBBuzman hekimlerinin konuya ilgilerinin giderek azaldığı gözlenmektedir. Bu durumun sebepleri bilinmemektedir. Bu çalışmada gelişmelerinve sorunların saptanması, çözüm önerileri sunulması amacıyla KBB Alerjik hastalıklardaki durumun belgelenmesi amaçlanmıştır.Gereç ve Yöntem; Bu makalede 41. Ulusal KBB-BBC kongresindeki oturumdaki konuşmalardan elde edilen veriler geliştirilerek,KBB’da alerjik hastalıklar alanındaki durum dökümante edilmiştir.Bulgular; 1999 yılında “Otolarengolojik Alerji Derneği” kurulmuştur. 1978 yılında başlayan, epidermal deri testi ve immünoterapiuygulamaları, 2000’li yıllarda ivme kazanmıştır. 2013 yılında KBB uzman hekimlerinin epidermal deri testi ve immünoterapi hizmetlerininSGK tarafından ödenmediği gerekçesi ile hastane idarecileri tarafından engellenmesi, konuyla ilgili uygulamaları sekteye uğratmıştır. KBBBBC Uzmanlık eğitimi çekirdek programında alerjik hastalıklarla ilgili yeterli sayıda başlık yer almaktadır. Tüm Ulusal KBB ve rinolojikongrelerinde alerjik hastalıklarla ilgili çeşitli sayıda ve konuda oturumlar yapıldığı görülmektedir. Günümüze kadar KBB’da alerjikhastalıklar konusunda ülkemizde 6 kitap basılmıştır. 2018 yılından beri alerji ve rinoloji konusunda çevrim içi yayın yapan, uluslararası birdergi yayınlanmaktadır.Sonuç; KBB uzman hekimlerinin alerjik hastalıklar konusuna ilgisini çekecek yeni stratejiler geliştirilmelidir. KBB alanında alerjiuygulamalarıyla ilgili değişim ve ortaya çıkan sorunlar düzenli olarak değerlendirilmelidir. Ortaya çıkan sorunlara alerji ile aktif ilgilenenKBB uzman hekimleri tarafından ortak çözümler geliştirilmelidir.Öğe Management of Epistaxis(Springer International Publishing, 2019) Durmuş, Kasım; Altuntaş, Emine Elif; Milkov, MarioEpistaxis is a common phenomenon in the emergency departments. Each year, nearly 5-10% of the public experience an active nasal bleeding. Among acute otorhinolaryngologic emergency disorders, epistaxis is the most common one and affects persons of all ages and both sexes. Its incidence is higher in males when compared to females. Most episodes are uncomplicated while 6% require medical attention. Epistaxis has a bimodal distribution with the frequency of occurrence peaking twice at the ages of 2-10 and 50-80. About 30% of children up to 5 years old have had at least one epistaxis. Its incidence is very low in babies and decreases after puberty. In autumn and winter, the incidence of epistaxis increases due to upper respiratory tract infections, overheating of closed areas, and lack of moisture. Epistaxis, which can be a severe or even fatal condition, refers to bleeding of nasal mucosa and is associated with significant morbidity and occasional mortality. Based on the primary bleeding site, epistaxis is defined as anterior or posterior. Typically, the origin of bleeding is the Kiesselbach’s plexus which is an anatomic network of vessels on the anterior portion of the nasal septum. Blood vessels within the nasal mucosa are superficial and therefore unprotected. In this chapter, management of epistaxis is discussed in all aspects. © Springer Nature Switzerland AG 2020.Öğe Nasal Nosocomial Myiasis Infection Caused by Lucilia Sericata Following Epistaxis and Nasal Packing: A Case Presentation(AVES, 2020) Bora, Adem; Ataş, Ahmet Duran; Altuntaş, Emine ElifThe aim of this case report was to present our clinical approach for a case wherein nasal packing was applied for epistaxis and nosocomial nasal myasis caused by Lucilia sericata was developed during the follow-up in the intensive care unit because of subarachnoid hemorrhage. Nasal packing was used for epistaxis during the anticoagulant treatment of a 79-year-old man who was hospitalized, followed up, and treated at the coronary intensive care unit for the diagnosis of congestive heart failure. The larvae of L. sericata were observed in the nasal cavity after the nasal packings were removed on the third day. Hospital-acquired myiasis is rarely seen in clinical settings. The most critical point in the prevention of myiasis is undoubtedly hygiene as well as the use of an air conditioning system in the ventilation of the entire hospital, especially in the intensive care units. The present case report is the first for nosocomial myiasis caused by Lucilia in Turkey. © Author(s).Öğe Retrospective evaluation of results of newborn hearing screening and importance of patient record system(2018) Bora, Adem; Durmuş, Kasım; Altuntaş, Emine ElifObjective: The aim of the present study was to evaluate hearing screening results of 3490 newborns who underwentnewborn hearing screening between 2015-2017 in Cumhuriyet University Faculty of Medicine Department ofOtolaryngology, to asses deficiencies of our record system, and to share our retrospective results by comparing with theresults in the literature.Method: Hearing screening results of infants who were born in Cumhuriyet University between March 2015 andFebruary 2017, were referred to neonatal intensive care or transferred from other out-of-town or inner city hospitals toour university was retrospectively evaluated in the present study.Results: There was a statistically significant difference for the left ear TEOAE test results and gender (p<0.05,p=0.016, x2=5.78). And also summarizes the distribution of ABR test results in terms of gender while failure rate wasstatistically significant in the right ear in terms of gender (p<0.05, p=0.022, x2=1.33).Conclusions: When results of the present study were evaluated, it was found that while they were similar to someresults in the studies on this issue in the literature, they showed great differences than some of them. Our main goal wasto evaluate insufficiencies in record systems of both our hospital and external centers while we were planning thepresent study. Our results revealed that these records were not paid enough attentions at external centers and our recordsystem had some insufficiencies.Öğe Retrospective evaluation of the correlation between climatic factors and peripheral vertigo(Sivas Cumhuriyet University, 2019) Bora, Adem; Durmuş, Kasım; Çam, Selim; Altuntaş, Emine ElifObjective: The present study was to examine seasonal distribution of vertigo and to retrospectively investigate the correlations between vertigo and climatic variables in a region, where continental climate is dominant. Method: Fifty two cases, who applied to our clinic with the complaint of vertigo in between July 2015 and June 2017 and were diagnosed with peripheral vertigo, were included in the study. Meteorological parameters were obtained from YYY weather station. Results: When examining the distribution of the cases by seasons; it was determined that although the number of cases increased in the autumn months. A statistically significant correlation also was not determined between seasonal parameters evaluated and vertigo (p>0.05). When regression analysis individually was performed in terms of causality between climatic parameters and vertigo, the causality in all variables, except for the minimum air temperature during the period of evaluation, was found to be significant. When the difference between sudden short term changes in seasonal variables and the values identified on the day of episode was evaluated, there was a statistically significant difference for all parameters of evaluation except for precipitation (p<0.05). Conclusions: The results of the study revealed that the number of cases increased in the months when seasonal changes with distinct differences of temperature occurred. The results of the related studies in the literature are different from each other. Therefore, we have concluded that it is possible to evaluate clearly the correlation between climatic parameters and vertigo only with studies involving different climatic regions.Öğe STANDARDIZATION OF CERVICAL VESTIBULAR EVOKED MYOGENIC POTENTIAL TESTS WITH AIR AND BONE CONDUCTION STIMULATION IN HEALTHY ADULTS(2020) Bora, Adem; Durmuş, Kasım; Altuntaş, Emine ElifObjective: The aim of this study was to obtain normative data on Cervical Vestibular Evoked Myogenic Potentials (cVEMP) test inadult age group to use as a differential diagnostic test in our clinic. Materials and Methods: This prospective study was conducted on 50 volunteers who were completely healthy, had no history of vestibular disorder and hearing loss, and had normal otoscopic and audiologic examination results at the Department of Ear-Nose-Throat. The p13 and n23 latency, p13-n23 interpeak latency and p13-n23 amplitude values of both ears of the subjects in the study were analyzed. Results: In the examination of mean values of cVEMP with air and bone conduction sound stimulation according to the genders, there was a statistically significant difference in the comparison of air conduction p13 latency, n23 latency and p13-n23 amplitude and bone conduction p13 latency (p <0.05). The air and bone conduction cVEMP test according to age groups was evaluated; a statistically significant difference was calculated according to the age groups in p13-n23 interpeak latency air conduction measurement and p13 and n23 latency bone conduction measurement values (p <0.05). Conclusion: In addition to the determination of normative values of our clinic in this study, we hope to make a contribution to the studies conducted on this matter in the literature through the results of the present study. Additionally, limit values of cVEMP test parameters assessed in the present study were also calculated. Determination of these values would be able to enable to form our standards to establish differential diagnosis of various diseases in the future.Öğe TEMPORAL KEMİKTE İZLENEN ANATOMİK VARYASYONLAR BELL PARALİZİNİN PATOGENEZİNDE ROLÜ OLABİLİR Mİ?(2024) Culha, Sümeyye Gencer; Çiftçi, Merve; Bora, Adem; Altuntaş, Emine ElifAmaç: Bell paralizisi (BP)' nin patogenezi günümüzde hala net olarak ortaya konabilmiş değildir. Anatomik olarak fasiyal kanalın çapının dar olmasının BP etyolojisinde rolü olabileceği yapılan çalışmalar ile gösterilmiştir. Ancak BP'li olgularda yüksek juguler bulbus, sinüs timpani derinliği, anterior yerleşimli sigmoid sinüs, geniş koklear aquaducktus ve geniş internal akustik meatus ile fasiyal paralizi arasında ki olası ilişkinin araştırıldığı bir çalışmaya ulaşamadık. Bu nedenle kliniğimizde son 5 yılda BP tanısı ile takip ve tedavileri yapılmış olguların temporal kemik BT'lerini değerlendirerek bu varyasyonların BP patogenezinde ki olası rollerini araştırmayı amaçladık. Gereç ve Yöntem: Retrospektif olarak kliniğimizde BP tanısı alan 110 hastanın temporal kemik bilgisayarlı tomografi (BT) görüntüleri; yüksek juguler bulb, sinüs timpaninin derinliği, anterior yerleşimli sinüs sigmoid, genişlemiş koklear aquaduckt ve genişlemiş internal akustik meatus varlığı açısından değerlendirildi. Olguların BP'si izlenmeyen tarafı kontrol grubu (Grup K) ve BP izlenen tarafları ise çalışma grubu (Grup BP) olarak kabul edildi. Bulgular: Değerlendirilen anatomik varyasyonlar açısından Grup BP ve Grup K arasından istatistiksel açıdan anlamlı farklılık yalnızca geniş internal akustik meatus da izlendi (p< 0,005). Cinsiyet özelinde yapılan grup içi ve gruplar arasında ki değerlendirmede de istatistiksel açıdan anlamlı bir farklılık izlenmedi. Sonuç: Bu retrospektif çalışmadan elde edilen sonuçlar yüksek juguler bulbus, sinüs timpani derinliği, anterior yerleşimli sigmoid sinüs, geniş koklear aquaducktus ve geniş internal akustik meatus ile BP arasında istatistiksel açıdan anlamlı bir ilişki olmadığını göstermektedir. Ancak geniş olgu serilerinde daha ayrıntılı görüntüleme ve radyolojik ölçüm yöntemleri kullanılarak bulgularımızın desteklenmesi gerektiği kanısındayız.
