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    Analysis of corneal densitometry and endothelial morphometry in patients with psoriasis
    (Elsevier, 2021) Yeter, Duygu Yalinbas; Bozali, Erman; Apa, Anil Selim; Tosun, Mustafa
    Background: To evaluate corneal endothelial properties and corneal densitometry values in patients with psoriasis and to compare the results with those of healthy controls. Methods: This prospective, comparative, and cross-sectional study included 106 eyes of 53 patients who were diagnosed with psoriasis and 106 eyes of 53 age-gender matched healthy controls. All patients were evaluated in terms of ocular surface tests such as Schirmer-1 and tear break-up time (TBUT). Corneal endothelial measurements were performed using noncontact specular microscopy. Corneal tomographic and densitometric measurements were obtained using the Scheimpflug imaging system. Measurements were also evaluated according to the psoriasis area and severity index (PASI) score. Results: The mean TBUT and Schirmer 1 test values were significantly lower in the psoriasis group than in the healthy controls (p = 0.02, p < 0.001, respectively). While the mean endothelial cell density was significantly lower in patients with psoriasis than the healthy controls (2389.9 +/- 314.9 cells/mm2 vs. 2512.4 +/- 289.7 cells/ mm2, p = 0.02), the mean average endothelial cell area, standard deviation of cell area, coefficient of variation of cell area were significantly higher in patients with psoriasis (426.6 +/- 62.7 mu m2 vs. 403.2 +/- 46.1 mu m2, p = 0.01; 206.4 +/- 52.3 mu m2 vs. 183.2 +/- 43.8 mu m2, p = 0.006; and 48.1 +/- 6.3% vs. 45.7 +/- 6.7%, p = 0.04, respectively). Most of the densitometry measurements in concentric zones were higher in patients with psoriasis than in healthy controls, but none of the differences reached statistical significance. Conclusions: A regular eye examination is crucial in patients with psoriasis because corneal structural and functional changes, particularly endothelial alterations, are of utmost importance in planning intraocular surgeries in patients with psoriasis.
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    Assessment by the Scheimpflug imaging system of corneal clarity and anterior segment properties in rosacea patients
    (Elsevier Science Inc, 2024) Bozali, Erman; Yeter, Duygu Yalinbas; Tosun, Mustafa; Apa, Anil Selim
    Objective: To evaluate the effects of rosacea on ocular surface changes such as alterations in dry eye parameters, corneal densitometry, and aberrations, in comparison with healthy controls. Methods: A total of 88 eyes of 44 patients diagnosed with rosacea and 88 eyes of 44 healthy controls were enrolled in this cross-sectional study. All participants underwent a comprehensive dermatologic and ophthalmic examination and Tear Break-Up Time (TBUT) and Schirmer-1 tests were performed. The rosacea subtype and Demodex count and OSDI scores of all participants were recorded. Corneal topographic, densitometric, and aberrometric measurements were obtained using the Scheimpflug imaging system. Results: The mean age of the 44 patients was 41.2 +/- 11.0 years of whom 31 (70.5%) were female. The mean TBUT and Schirmer-1 test values were significantly decreased and OSDI scores were significantly increased in the rosacea group compared to healthy controls (p < 0.01 for all). The most common subtype of rosacea was erythematotelangiectatic rosacea (70.4%). The severity grading of rosacea revealed that 18 (40.9%) patients had moderate erythema. The median (min-max) Demodex count was 14.0 (0-120) and the disease duration was 24.0 (5-360) months. The comparison of the corneal densitometry values revealed that the densitometry measurements in all concentric zones, especially in central and posterior zones were higher in rosacea patients. Corneal aberrometric values in the posterior surface were also lower in the rosacea group compared to healthy controls. The topographic anterior chamber values were significantly lower in the rosacea group.
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    Pediatric Open Globe Injury in a University-Based Tertiary Hospital in the Anatolian Region
    (Marmara Univ, Inst Health Sciences, 2022) Bozali, Erman; Yeter, Duygu Yalinbas; Apa, Anil Selim; Ozec, Ayse Vural; Erdogan, Haydar
    Objective: Evaluation of the epidemiological and clinical features of pediatric open globe injury.Methods: Medical records of 51 patients under the age of 18 who presented to the emergency department with open globe injury (OGI) between 2009 and 2021 were evaluated retrospectively. Patient demographics, Birmingham Eye Trauma Terminology (BETT) category, pediatric ocular trauma score (POTS), visual acuity (VA), site of injury, and seasonal distribution were evaluated.Results: Of all patients included, 40 (78.4%) were male, 11 (21.6%) were female, and the mean age was 9.6 +/- 5.2 years. Zone I injury was detected in 31 (60.8%) patients. The most common cause of injury was sharp objects such as metal or wood splinters. Of all injuries, 29 (56.9%) occurred outdoors. Ocular trauma occurred more frequently in boys, especially in the summer months. Initial VA was less than 0,1 in 21 (41.2%) of the patients, between 0.1-0.5 in 9 (17.6%) and 0.6 and above in 5 (9.8%) patients. At the final visit, VA was less than 0.1 in 9 (17.6%) patients, 0.1-0.5 in 10 (19.6%) patients, and 0.6 and above in 18 (35.3%) patients. Final VA was related to the Zone and was lower as the Zone increased (p:0.011). VA and POTS scores were positively correlated at the final visit (p=0.001).Conclusion: It is substantial for emergency physicians to have a comprehensive understanding of pediatric globe injuries so that children with suspected ocular trauma should be evaluated by an ophthalmologist to prevent medicolegal problems.