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    COVID-19 Co-infection in a patient with Crimean Congo Hemorrhagic Fever: A Case Report
    (Ankara Microbiology Soc, 2021) Buyuktuna, Seyit Ali; Hasbek, Mursit; Oksuz, Caner; Baysal, Cihad; Oz, Murtaza; Elaldi, Nazif; Bakir, Mehmet
    Crimean-Congo Hemorrhagic Fever (CCHF) is an acute viral zoonotic disease. Coronavirus disease-2019 (COVID-19) is a newly emerging viral disease and it is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). In this article, a case diagnosed with CCHF and COVID-19 coinfection confirmed by the polymerase chain reaction (PCR) method and its management was presented. A thirty-five years old female patient admitted to the hospital with the complaint of fever for one day and common body pain. It was learned that three days before the onset of her complaints, she removed a tick adhering to the anterior abdominal wall with no precaution. Her body temperature was 38 degrees C degrees and her respiratory rate was 22 per minute. The leucocyte count was 3660/mm(3) and the platelet count was 138.000/mm(3). It was determined that prothrombin time was 15.4 seconds, international normalized ratio (INR) was 1.35 seconds, and D-dimer level was 1310 ng/ml. The patient was hospitalized with prediagnosis of CCHF. Supportive treatment was started. On the second day at the clinical follow-up of the patient, complaints of sore throat and cough without sputum started. A combined nasopharyngeal and throat swab sample was taken from the patient because of the suspicion of COVID-19. COVID-19 PCR test result was reported as positive. Favipiravir treatment was started. The CCHF-PCR test, which was studied from the serum sample sent to the Microbiology Reference Laboratories was reported as positive. From the third day of favipiravir treatment; the patient did not have a fever and her complaints regressed. On the ninth day of her hospitalization, she was discharged. In this case; it is important to show that both diseases, especially in regions where CCHF disease is endemic, can be confused due to the similarity of the clinical picture with COVID-19 and to know that they can coexist.
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    Evaluation of surgical antimicrobial prophylaxis compliance: A multicenter point prevalence study
    (Elsevier Inc., 2025) Kıymaz, Yasemin Çakır; Karakök, Taliha; Büyükkörük, Merve; Manavlı, Barış; Baysal, Cihad; Karaşın, Muhammed Fatih; Işık, Merve Türker
    Background: This study aimed to determine the frequency of compliance with surgical antimicrobial prophylaxis (SAP) in Turkey and to identify the causes for noncompliance. Methods: This multicenter, prospective, point prevalence study was conducted in 8 hospitals from different regions of Turkey. Patients over 18 years who underwent SAP in all hospital surgical units were included. The SAP compliance assessment was carried out under 5 headings: unnecessary prophylaxis, inappropriate drug choice, prolonged prophylaxis, inappropriate dose interval, and inappropriate dosage. Results: The study included 541 patients from 8 centers. About 52.7% (n = 285) were female and the median age was 54 years (min-max: 18-94). Orthopedics (23.7%) and general surgery (22.2%) were the most common specialties. SAP compliance was 14%. The specialty with the highest rate of inappropriate SAP was orthopedics (97%) and the lowest rate was in ophthalmology (25%). The most common causes of inappropriate SAP were prolonged prophylaxis (92.0%) and inappropriate dose interval (84.6%). Multivariate logistic regression analysis revealed that prolonged surgical time, American Society of Anaesthesiologists (ASA) score 3, and some specialties increased the risk of noncompliance with surgical prophylaxis. Conclusions: This study showed that SAP compliance is low in Turkey and that inappropriateness is caused mostly by prolonged and inappropriate antimicrobial use. © 2025 Association for Professionals in Infection Control and Epidemiology, Inc.
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    Mortality rates and risk factors associated with mortality in patients with stenotrophomonas maltophilia primary Bacteraemia and Pneumonia
    (Elsevier Science Inc, 2025) Hasbek, Mursit; Aldemir, Ozlem; Kiymaz, Yasemin cakir; Baysal, Cihad; Yildirim, Dilara; Buyuktuna, Seyit Ali
    This study aims to evaluate the risk factors associated with the mortality of S. maltophilia infections. Patients aged 18 years and older with S. maltophilia infection. Patients were divided into two groups primary bacteraemia and pneumonia. Of 176 S. maltophilia infections, 85 (48.2 %) were classified as bacteremia and 91 (51.8 %) as pneumonia. The mortality rate was 56 %, with no significant difference observed between the groups. Invasive mechanical ventilation, history of carbapenem use, and high Charlson Comorbidity Index (CCI) were significantly higher in the pneumonia group. In univariate analysis, higher Acute Physiology and Chronic Health Evaluation (APACHE) II score, higher Sequential Organ Failure Assessment (SOFA) score, and use of total parenteral nutrition (TPN) were identified as independent risk factors for 28-day mortality. This study demonstrates a mortality rate of 56 % in S. maltophilia infections and provides concrete data on risk factors for mortality.
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    Spontaneous bacterial peritonitis due to Brucella in an HBV-positive cirrhotic patient
    (Elsevier, 2025) Kiymaz, Yasemin Cakir; Yesildag, Sumeyye Kara; Baltaci, Sevgi; Baysal, Aysenur Comez; Baysal, Cihad; Keskin, Ertugrul; Bozkurt, Suna
    Spontaneous bacterial peritonitis (SBP) is a severe complication of cirrhosis, occurring in approximately 15 % of cirrhotic patients. The most common causative pathogens of SBP are Escherichia coli and Klebsiella pneumoniae. Although brucellosis can cause various complications, it is a rare cause of peritonitis. Herein, we report a case of a 30-year-old male with chronic hepatitis B who presented with fever, night sweats, weight loss, abdominal pain, and distension. Brucella spp. was isolated from blood and peritoneal fluid cultures. The patient fully recovered following six weeks of treatment with oral doxycycline (100 mg twice daily) and rifampicin (600 mg/day). No relapses or complications were observed during follow-up.