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  1. Ana Sayfa
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Yazar "Caglayan, Ilkin Seda Can" seçeneğine göre listele

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    Associations Between COVID-19 Vaccination Status and Persistent Symptoms: A Prospective Study of Reproductive-Age Women
    (Wiley, 2025) Caglayan, Ilkin Seda Can; Demirel, Gulbahtiyar; Can, Ceren Eda
    Objective: The present study was conducted to determine the relationship between prolonged complaints of women who had COVID-19 infection and whose symptoms persisted and their vaccination status against COVID-19. Methods: This prospective observational study consisted of three groups [The Unvaccinated Group (Control Group: 89), the BioNTech Vaccine Group (114 people), and the Sinovac Vaccine Group (84 people)]. In this study, which included 287 women, prolonged COVID-19 symptoms in their spouses were also questioned. Information was obtained from the participants in the form of questions and answers under outpatient clinical conditions 2 months after their recovery. Women between the ages of 18-45 who had regular menstrual periods in the last 6 months before the pandemic, those whose COVID-19 test was negative and those who received a single dose of vaccine in the vaccinated group were included in the study. Results: The rates of loss of taste and prolonged symptoms of high fever in Sinovac-vaccinated participants were lower than in the other groups in the present study (p < 0.05). A total of 40.5% of those who were vaccinated with Sinovac after COVID-19 had a menstrual cycle length of every 28-40 days, which was higher than the percentage of participants in other groups, and 40.5% of those in this group did not have menstrual pain. Additionally, the menstrual period length of 62.3% of the participants who received the BioNTech vaccine increased (p < 0.05). This increase is higher than the participants in the other group. Conclusion: The study indicated that certain prolonged symptoms of COVID-19 infection were less common among participants vaccinated with Sinovac. In this group, the menstrual cycle length increased, while menstrual pain decreased.
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    Effects of the COVID-19 Pandemic on Mental and Sexual Health of Women
    (2024) Caglayan, Ilkin Seda Can; Can, Ceren Eda; Demirel, Gulbahtiyar
    Objective: This study was conducted to determine the effects on women's mental and sexual health of the COVID-19 pandemic. Materials and Methods: The research in the case-control involved 315 women, out of which 171 were part of the control group. These women had no history of COVID-19 infection before and were free from any mental or physical health issues. The remaining 144 female participants formed the case group. They had contracted COVID-19 disease at least two months ago and had tested negative. Results: Based on the study data, women who have had COVID-19 show a higher rate of moderate to severe depression (p
  • Küçük Resim Yok
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    Evaluation of Serum Adipokine Levels in Girls With Central Precocious Puberty
    (Wiley, 2024) Caglayan, Ilkin Seda Can; Celik, Nurullah; Bolat, Serkan
    Purpose: Adipose tissue has an important endocrine function by secreting a variety of hormones known as adipokines, such as Visfatin, Omentin-1 and Chemerin. On the other hand, these hormones are also secreted from places other than fatty tissues in the girl's genital system. The goal of this study was to demonstrate the secretory status of adipokines in patients with central precocious puberty (CPP) and their utility in the diagnosis of precocious puberty. Method: A total of 105 patients were included in the study (53 in the CPP group and 52 in the control group). The following were used as the CPP diagnostic criteria; breast development, basal LH measurement higher than 0.3 IU/L, peak LH level >= 5 IU/L, peak LH/FSH ratio >= 0.66 (after 0.1 mg GnRH stimulation test) and a difference of at least 1 year between bone and chronological age. Results: A statistically significant difference was detected between the groups in serum Omentin-1 and Chemerin levels, and no significant differences were detected between the groups in Visfatin values. The cut-off values for the diagnosis of CPP were calculated as <= 48.9 with 81% sensitivity and 54% specificity for Omentin-1, and as >= 417 with 85% sensitivity and 60% specificity for Chemerin. Conclusion: In our study, we found that Omentin-1 level decreased and Chemerin level increased in lean girls with CPP. More studies are needed to elucidate how adipokines play roles in explaining the onset of CPP, and whether they may be used as a reliable marker for the diagnosis of CPP.

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