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Öğe Absence of interthalamic adhesion in a female cadaver: A case report(2007) Cimen, Mehmet; Erdil, F. Hayat; Kalhan, Keziban; Tetiker, Hasan; Karacan, AlperThe interthalamic adhesion is a midline structure that connects each thalami at the medial surface. It is about 1 cm in dimension. Sometimes it cannot be found. It has been questioned whether there is a correlation between absence of the interthalamic adhesion and pathological conditions. Therefore various clinical and postmortem studies carried on related with the absence or presence of this structure. In this case, we observed that the interthalamic adhesion was absent in a 39-year-old female cadaver. We presented our case and discussed the literature to contribute the postmortem investigations.Öğe Anatomical variants of the lateral femoral circumflex artery: An angiographic study by Fukuda H, Ashida M, Ishii R, Abe S, Ibukuro K, Surg Radiol Anat (2005) 27 : 260-264(SPRINGER, 2007) Cimen, Mehmet; Erdil, F. Hayat; Sabancyodullary, Vedat; Kopar, M. Ylkay…Öğe Definition of variational arteries that supply the suprarenal gland(WILEY-LISS, 2007) Cimen, Mehmet; Erdil, F. Hayat; Tetiker, Hasan…Öğe Dermatoglyphic features in patients with multiple sclerosis(RIYADH ARMED FORCES HOSPITAL, 2014) Sabanciogullari, Vedat; Cevik, Seyda; Karacan, Kezban; Bolayir, Ertugrul; Cimen, MehmetObjective: To examine dermatoglyphic features to clarify implicated genetic predisposition in the etiology of multiple sclerosis (MS). Methods: The study was conducted between January and December 2013 in the Departments of Anatomy, and Neurology, Cumhuriyet University School of Medicine, Sivas, Turkey. The dermatoglyphic data of 61 patients, and a control group consisting of 62 healthy adults obtained with a digital scanner were transferred to a computer environment. The ImageJ program was used, and atd, dat, adt angles, a-b ridge count, sample types of all fingers, and ridge counts were calculated. Results: In both hands of the patients with MS, the a-b ridge count and ridge counts in all fingers increased, and the differences in these values were statistically significant. There was also a statistically significant increase in the dat angle in both hands of the MS patients. On the contrary, there was no statistically significant difference between the groups in terms of dermal ridge samples, and the most frequent sample in both groups was the ulnar loop. Conclusions: Aberrations in the distribution of dermatoglyphic samples support the genetic predisposition in MS etiology. Multiple sclerosis susceptible individuals may be determined by analyzing dermatoglyphic samples.Öğe Determination of Lateral Ventricle and Brain Volume in Children with Stereological Method Using MRI(SOC CHILENA ANATOMIA, 2013) Karacan, Keziban; Kosar, Mehmet Ilkay; Cimen, Mehmet; Solak, Orhan; Sahin, BunyaminAlthough brain development is most active during the intrauterina period of life, the processes of myelination and arborization affect the structure of the brain throughout childhood and adolescence. Brain development is also very active in the early years of a child's life, and continues to be so for approximately 15 years after gestation. Volumetric changes in the brain are effected by sex. Understanding the variability of human brain volume during development is important for the interpretation of childhood neuroimaging studies. Hence the aim of this study is to determine the effects of sex difference on brain volume (BV), lateral ventricle volume (LV) and the ratio of brain volume and lateral ventricle volumes as a percentage (RLBV%) of 90 healthy children between the ages of 6-17 according to their sex with MRI. These children were divided into three age groups of 6-9, 10-13 and 14-17 also BV, LV were calculated using the Cavalieri principle, which is classified as a stereological method and than RLBV% were calculated. Results: The BV of age group 6-9 was significantly smaller than the other two age groups (P < 0.05). General average BV of the age group 10-13 was higher than the other two age groups but this difference is insignificant. When the groups were compared according to sex, there was no important difference between girls and boys (P > 0.05). General average LV of the age group 6-9 was higher than the other two age groups but this difference insignificant. Moreover there was no sex difference. This study was presented that BV was continued to increase until the ages 10-13 for both of the genders. While LV was increased until the ages 10-13 for boys, it was had a negative relationship with changes of BV for girls.Öğe Diploe thickness and cranial dimensions in males and females in mid-Anatolian population: An MRI study(ELSEVIER IRELAND LTD, 2012) Sabanciogullari, Vedat; Kosar, Mehmet Ilkay; Salk, Ismail; Erdil, Fatma Hayat; Oztoprak, Ibrahim; Cimen, MehmetBackground: The objective of this study is the classification of the thickness of diploe and dimensions of cranium at different points of cranium in men and women according to age groups. Material and method: In the radiology archive, measurements were made at different points in magnetic resonance (MR) images of 305 (188 females and 117 males) patients, the average ages of whom were 40.98 +/- 20.44 (age range: 4-90) and who had no disorder of the bones. To determine diploe thickness, midfrontal, back and front bregma, lambda, opisthocranion and euryon points were used in the measurement. As for the determination of cranial volume, distances between glabella-opisthocranion, basion-vertex, basion-opisthion, euryon-euryon, nasion-basion, nasion-bregma, bregma-lambda and lambda-opisthocranion were measured. The data were loaded to Statistical Package for the Social Sciences (SPSS) 16.0 program. T-test, Mann-Whitney U, Pearson correlation coefficient and Kruskal-Wallis variance analysis were used in the statistical assessment. Results with a p value smaller than 0.05 were accepted as significant. Results: There was a statistically significant positive correlation between age and diploe thickness in all measurement points. The diploe thickness was also increased with age (p < 0.05). In all points, average diploe thickness was higher in age 61 and over than the other groups (p < 0.001). At the same time, diploe thickness in parietal bones was lower than frontal and occipital bones in both sexes. According to craniometric results cranium in males was bigger (p < 0.001). While the distance between glabella-opisthocranion increased in both sexes aged 61 and over, basion-vertex height decreased in women in the same group (p < 0.05). Interestingly, there was no meaningful statistical difference among age groups in terms of maximum cranial width (p > 0.05). Foramen magnum length decreased related to age in both men and women (p < 0.001). Conclusion: These results related to diploe thickness and cranium dimension may be leading in the determination of sex and age; surgical interventions to the cranium and bone graft choice may increase the reliability of the operation. (C) 2011 Elsevier Ireland Ltd. All rights reserved.Öğe Estimation of the femur length from its proximal measurements in Anatolian Caucasians by artificial neural networks(TAYLOR & FRANCIS LTD, 2016) Otag, Ilhan; Otag, Aynur; Akkoyun, Serkan; Cimen, MehmetFemora are a well preserved section of the skeleton after death. Therefore, they are commonly used in the field of forensic sciences, physical anthropology and anatomy. In addition, femur morphometry is helpful in finding sex or side (left or right) differences. The femur also shows characteristics of certain populations. Femur length is important for calculation of individual stature. In this study, the artificial neural network method was used to estimate femur length. In total, 230 femora exemplar were used. The three input parameters of the method were the distance between trochanter major top point and trochanter minor bottom point, the diameter of caput femoris and the diameter of collum femoris. By using these parameters, the artificial neural network estimation on femur length was performed. The results show that the method is capable of performing this estimation. In addition, sex discrimination was performed and achieved with 82% accuracy. As well as the identification of sex or side differences, morphometry of the proximal femur is necessary and important for surgical procedures.Öğe Evaluation of the Vertebral Artery by 3D Digital Subtraction Angiography(SOC CHILENA ANATOMIA, 2014) Tetiker, Hasan; Cimen, Mehmet; Kosar, Mehmet IlkayThe objective of the present study is to determine origin, entry level to the transverse foramen and diameter according to sex and side through 3D angiographic images of seventy-nine vertebral arteries obtained using DSA imaging method. During radiological evaluation, axial, coronal and sagittal images of the artery were used. Data of our study was uploaded to SPSS 14.0 program and significance test and Mann Whitney-U test of the difference between two means were used to evaluate the data. While 76 of the vertebral arteries (96.2%) were originating from the subclavian artery, 3 of them (3.8%) were directly originating from aortic arch. In 67 of 76 the vertebral arteries originating from the subclavian artery were entering through C6, 6 through C7, 2 through C5 and one through C4 transverse foramen. It was seen that one of 3 the vertebral artery originating from aortic arch was entering through C6, one through C7 and the other through C4 transverse foramen. While the mean diameter of the vertebral artery was 3.88 +/- 0.71 mm at the right side (3.99 mm in men, 3.66 mm in women), the mean diameter at the left side was 4.15 +/- 1.05 mm (4.23 mm in men, 4.06 mm in women).Öğe Frontal Lobe Morphometry with MRI in a Normal Age Group of 6-17 Year Olds(KOWSAR PUBL, 2013) Kosar, M. Ilkay; Otag, Ilhan; Sabanciogullari, Vedat; Atalar, Mehmet; Tetiker, Hasan; Otag, Aynur; Cimen, MehmetBackground: Morphometric data of the frontal lobe are important for surgical planning of lesions in the frontal lobe and its surroundings. Magnetic resonance imaging (MRI) techniques provide suitable data for this purpose. Objectives: In our study, the morphometric data of mid-sagittal MRI of the frontal lobe in certain age and gender groups of children have been presented. Patients and Methods: In a normal age group of 6-17-year-old participants, the length of the line passing through predetermined different points, including the frontal pole (FP), commissura anterior (AC), commissura posterior (PC), the outermost point of corpus callosum genu (AGCC), the innermost point of corpus callosum genu (IGCC), tuberculum sella (TS), AGCC and IGCC points parallel to AC-PC line and the point such line crosses at the frontal lobe surface (FCS) were measured in three age groups (6-9, 10-13 and 14-17 years) for each gender. Results: The frontal lobe morphometric data were higher in males than females. Frontal lobe measurements peak at the age group of 10-13 in the male and at the age group of 6-13 in the female. In boys, the length of FP-AC increases 4.1% in the 10-13 age group compared with the 6-9-year-old group, while this increase is 2.3% in girls. Conclusion: Differences in age and gender groups were determined. While the length of AGCC-IGCC increases 10.4% in adults, in children aged 6-17, the length of AC-PC is 11.5% greater than adults. These data will contribute to the preliminary assessment for developing a surgical plan in fine interventions in the frontal lobe and its surroundings in children.Öğe Functional morphology of arteriovenous anastomoses on rat ovary(Univ Zulia, Facultad Ciencias Veterinarias, 2024) Cimen, Kaan; Cimen, MehmetThis study aims to show the morphology of the structure involved in the function of arteriovenous anastomoses (AVA) under electron microscope. The study used 20 adult females of Rattus norvegicus. Ovarian tissue samples were fixed in 3% Glutaraldehyde in phosphate buffer, and then post-fixed in increasing concentrations of Ethanol, tissues were embedded in Epon resin. Semi-thin tissue sections were double stained with Uranyl acetate saturated in 70% Ethanol and lead Citrate. The ultrathin sections were examined in a JEOL 100 C electron microscope. In the opened AVA section, tunica intima, tunica media, and adventitia layers were observed in the vessel wall structure. The endothelial cell was present in the tunica intima, and the lumen was open. Thick layered smooth muscle cells were found in the tunica media. The muscles were arranged inner longitudinally and outer circularly. The internal elastic membrane lies between the circular and longitudinal smooth muscle. In another section taken from the tunica adventitia, fibroblasts were observed between dense elastic and collagen fibrils. The longitudinal smooth muscle was contracted in the closed AVA section, and the lumen appeared in the typical asterisks shape. This study showed the functional morphology of the AVA's and detailed vessel wall structures in the rat ovary. Lumen structure with open and closed AVAs is also shown. With observations from this study, the functional properties of the formations in the AVA wall structure are explained in the rat ovary.Öğe Geometric analysis of medio-lateral position of patella: A new measuring tool(MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2014) Otag, Aynur; Otag, Ilhan; Sabanciogullari, Vedat; Cimen, MehmetBackground: Evaluation of medio-lateral position of patella is necessary for diagnosis and treatment of patellofemoral diseases. Objective: In the present study, we aimed to evaluate medio-lateral patellar position differences and to define a new practical measuring tool which enables us to analyze relationships of the points at the knee. Materials and Methods: Total of 120 healthy volunteers (60 men and 60 women) were included in our study and both of their knees were measured. In the research, the gender groups and right-left differences were evaluated. In the measurements, a four-lever measuring tool designed for this study was used. The four anatomic points of the knee which are center of patella, epicondylus lateralis, epicondylus medialis and middle point of tuberositas tibiae were used. Results: While patella is 76% lateral in the right knee, it is 90% lateral in the left knee in men. As for woman, while it is 50% lateral in the right-knee, it is 30% lateral in the left-knee. In medio-lateral patellar position, while bilateral asymmetry is 28% in men, it is 50% in women. In measurements of knees of women and men, significant differences were detected both in the right and left knees (P < 0.05 and P < 0.001). Conclusion: The patellofemoral order differences between men and women can explain anatomic reasons of patellofemoral diseases, which are encountered more in women than men.Öğe Left pulmonary agenesis(DRUNPP-SARAJEVO, 2011) Sabanciogullari, Vedat; Gumus, Cesur; Erdil, F. Hayat; Cimen, MehmetLung agenesis is a rare congenital anomaly. It can be found single or double sided. While, double sided agenesis couldn't been survive, in single cases survive until adult or more advence of living is possible. This anomaly is generally diagnosed in childhood. However, incase if, unilateral pulmonary agenesis doesn't accompany with any other the serious anomaly, the asymptomatic cases are detected incidentally in advanced age. Cases associated with other system anomalies have a ratio with 60%. In our study 17-year-old female patient who had left pulmonary agenesis found by computed tomography. Since of its clinical importance this anomaly presented with the related literature.Öğe Magnetic resonance imaging mesencephalic tectum dimensions according to age and gender(RIYADH ARMED FORCES HOSPITAL, 2013) Sabanciogullari, Vedat; Salk, Ismail; Balaban, Hatice; Oztoprak, Ibrahim; Kelkit, Seref; Cimen, MehmetObjective: To analyze and classify normal MRI tectum length and colliculus dimensions according to age and gender. Methods: Tectum length and colliculus diameters were measured on the T1 midsagittal and axial cranial MR images in the radiology archive of 532 (344 women, 188 men) patients aged 37.36 +/- 21.49 (range: 4-91) years old on average, and with no disorders affecting the mesencephalic tectum. All 532 patients underwent clinical MR imaging of the cranium at the MRI Unit of Sivas Numune Hospital and Sivas Cumhuriyet University Hospital, Sivas, Turkey between February and December 2011. Results: Although there was a positive linear correlation between tectum length and age, there was a negative correlation between the anteroposterior diameter of the colliculus superior and colliculus inferior and age (p<0.01). While tectum length (M3) increases with age, the anteroposterior diameter of the colliculus superior and inferior (M1 and M2) decreased (p<0.01). The colliculi were larger, and the tectum was longer in men. Although there was no difference in size between right and left superior colliculi, the left colliculus inferior was larger than the right one. Conclusion: In addition to the fact that normal mesencephalic tectum dimensions provide information on the brain development of individuals, they may also be beneficial for the detection and treatment of related pathologies. Neurosciences 2013; Vol. 18 (1): 33-39Öğe Morgagni hernia with pectum carinatum in a male cadaver(2009) Sabanciogullar, Vedat; Kopar, M. ?lkay; Erdil, F. Hayat; Cimen, MehmetWe present a case of 74-years old male cadaver in which morgagni hernia and associated pathologies was observed during the routine dissection. Besides the hernia, pectum carinatum, sliding hernia and hydronephrosis at the right kidney were strike findings as an associated anomalies. Morgagni hernia is the rarest one among all the diphragmatic hernias, associated with serious anomalies. Since it has a clinical importance, precise anatomical occupation and definition of this variation on a cadaver as well as the associate anomalies is being reported by comparing with other related literature, to establish occurence pattern and importance of the operational base of morgagni hernia.Öğe MORGAGNI HERNIA WITH PECTUM CARINATUM IN A MALE CADAVER(PROFESSIONAL MEDICAL PUBLICATIONS, 2009) Sabanciogullar, Vedat; Kopar, M. Ylkay; Erdil, F. Hayat; Cimen, MehmetWe present a case of 74-years old male cadaver in which morgagni hernia and associated pathologies was observed during the routine dissection. Besides the hernia, pectum carinatum, sliding hernia and hydronephrosis at the right kidney were strike findings as an associated anomalies. Morgagni hernia is the rarest one among all the diphragmatic hernias, associated with serious anomalies. Since it has a clinical importance, precise anatomical occupation and definition of this variation on a cadaver as well as the associate anomalies is being reported by comparing with other related literature, to establish occurence pattern and importance of the operational base of morgagni hernia.Öğe Morphometry of corpus callosum related with gender and age: Magnetic resonance imaging study(2012) Kosar, Mehmet Ilkay; Erdil, Fatma Hayat; Sabanciogullari, Vedat; Karacan, Keziban; Cimen, Mehmet; Atalar, MehmetObjective: The corpus callosum (CC) is an important structure of connecting the two cerebral hemispheres. The purpose of this study was to examine the morphometry of the CC of normal cases and its relationship with gender and age. Methodology: Morphometric measurements of the corpus callosum were made on MR imaging in the mid-sagittal plane in 42 male and 48 female total 90 healthy subjects, age range was 6-17 year-old. Age of the cases were divided into three group as 6-9, 10-13 and 14-17 year-old. The length was measured by drawing a straight line at greatest antero-posterior diamater of CC, a perpendicular at its midline, anterior, posterior and medium segments of CC were measured. In addition as a result of these morphometric measurements index of corpus callosum (CCI) was calculated for every cases. Statistical analysis was performed by One-Way ANOVA- Tukey test, Independent Sample t test, Kruskal-Wallis test and Mann - Whitney U test. Results: Without considering sex between the age group, antero-posterior, anterior, posterior and medium segments diamaters of CC was found statistically significance (p<0.05) while analysis of CCI values was not found significant (p>0.05). Conclusions: These datas can be used as morphometric guide, for evaluation of the CC specially in years 6-17 age group.Öğe Morphometry of Corpus Callosum Related with Gender and Age: Magnetic Resonance Imaging Study(PROFESSIONAL MEDICAL PUBLICATIONS, 2012) Kosar, Mehmet Ilkay; Erdil, Fatma Hayat; Sabanciogullari, Vedat; Karacan, Keziban; Cimen, Mehmet; Atalar, MehmetObjective: The corpus callosum (CC) is an important structure of connecting the two cerebral hemispheres. The purpose of this study was to examine the morphometry of the CC of normal cases and its relationship with gender and age. Methodology: Morphometric measurements of the corpus callosum were made on MR imaging in the mid-sagittal plane in 42 male and 48 female total 90 healthy subjects, age range was 6-17 year-old. Age of the cases were divided into three group as 6-9, 10-13 and 14-17 year-old. The length was measured by drawing a straight line at greatest antero-posterior diamater of CC, a perpendicular at its midline, anterior, posterior and medium segments of CC were measured. In addition as a result of these morphometric measurements index of corpus callosum (CCI) was calculated for every cases. Statistical analysis was performed by One-Way ANOVA- Tukey test, Independent Sample t test, Kruskal-Wallis test and Mann - Whitney U test. Results: Without considering sex between the age group, antero-posterior, anterior, posterior and medium segments diamaters of CC was found statistically significance (p<0.05) while analysis of CCI values was not found significant (p>0.05). Conclusions: These datas can be used as morphometric guide, for evaluation of the CC specially in years 6-17 age group.Öğe Radiological Investigation of the Lumbosacral Region Anomalies in Patients with Abdominopelvic Complaints(ORTADOGU AD PRES & PUBL CO, 2010) Sabanciogullari, Vedat; Erdil, F. Hayat; Cimen, MehmetObjective: Aim of this study was to determine frequency of vertebral congenital anomalies of the lumbosacral region in the cases with abdominopelvic region complaints. Material and Methods: Direct urinary system graphies of patients between the ages 17-74 obtained from urology and physical therapy department archives were evaluated retrospectively. Mean age of the cases was 44.31 + 1.35. Of 755 evaluated graphies, 354 belonged to males and 401 to females. Lumbarization, sacralisation and spina bifida occulta were investigated on radiographies. Chi-square test was used for statistical analysis. Results: The number of cases with detected anomalies in lumbosacral region were 143 (18.9%). Distribution of the observed anomalies were as follows: 77 (10.2%) cases had lumbalization, 42 (5.6%) had sacralisation and 24 (3.2%) spina bifida occulta. While the most common observed anomaly with lumbalization cases were lumbar disc hernia, osteoporosis and urinary tract infection; cases with spina bifida occulta had lumbar disc hernia in two of cases, benign prostatic hyperplasia in two of cases, osteoporosis in one of case, urolithiasis in one of case. In 15 cases clinically diagnosed as sacralization, the most common accompanying disorder was lumbar disc hernia. Lumbosacral region anomalies detected in 64 of females and in 79 of males. Presented anomalies in female cases were 43 (10.7%) lumbalization, 11 (2.7%) sacralisation and 10 (2.5%) spina bifida occulta. Anomalies observed in 79 male cases were 34 (9.6%) lumbalization, 31 (8.8%) sacralisation and 14 (4%) spina bifida occulta. In comparison of the frequency of anomalies between to females and males, the differences were statistical significant (p= 0.002). Conclusion: We suppose that the information on the frequency of lumbosacral congenital surgical operations on this region as well as for investigating the etiology of low back pain and many other disorders involving lumbosacral area.Öğe A rare variation of the right middle suprarenal artery(ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2007) Cimen, Mehmet; Erdil, F. Hayat; Kosar, M. Ilkay; Sabanciogullari, VedatAccording to general knowledge, the suprarenal. gland is supplied by three sources: the phrenic artery, the abdominal. aorta and the renal artery. Since the gland tacks a hilus, and particularly because of its clinical importance, anatomical arterial sources and branching is still not uniform and it needs to be determined by detail. In this study, the right middle suprarenal artery arising from the right renal artery was observed on the right side of a 45-year-old mate cadaver. (c) 2006 Published by Elsevier GmbH.Öğe The Relationship between Total Calvarial Thickness and Diploe in the Elderly(SOC CHILENA ANATOMIA, 2013) Sabanciogullari, Vedat; Salk, Ismail; Cimen, MehmetThe aim of this study is the classification of the thickness of diploe, lamina externa, lamina interna and total calvarial thickness at different points of cranium in elderly men and women. In the radiology archive, measurements were made at different points in cranial MR images of 220 (110 females, 110 males) patients, the average ages of whom were 73.23 +/- 8.40 (age range: 61-90) and who had no disorder of the bones. Diploe thickness, lamina externa, lamina interna and total calvarial thickness were measured in eight points of the calvaria. Midfrontal point, back and front bregma, lambda, opisthocranion and euryon points were used in the measurement. The data was loaded to SPSS 16.0 program. T-test, Mann-Whitney U, Pearson correlation coefficient and Kruskal Wallis variance analysis were used in the statistical assessment. Results with a p value smaller than 0.05 were accepted as significant. There was statistically significant difference in total cranial thickness between males and females in the right euryon point only. Average total calvarial thickness at right euryon point was higher in females (6.20 +/- 0.78 mm) than in males (5.96 +/- 0.68 mm) (p=0.02). Average diploe thickness was higher in female than male except for point of bregma back (p<0.05). There was positive linear correlation between diploe thickness and age except for opisthocranion, right euryon and 1cm inferior to lambda. These results related to diploe thickness and cranium thickness may be leading in the determination of sex and age; surgical interventions to the cranium and bone graft choice and may increase the reliability of the operation.
