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    Aspiration and Death from Amitraz-Xylene Poisoning
    (Medi+World Int, 2006) Beyaztas, Fatma Yucel; Gursoy, Sinan; Demirel, Yeltekin; Kaygusuz, Kenan; Mimaroglu, Caner
    Amitraz is an acaricide and insecticide indicated for the treatment of dogs and for the control of ticks and mites in cattle and sheep. We report the clinical, laboratory and postmortem features of a suicide case by ingestion of amitraz. The major clinical findings were unconsciousness, respiratory failure requiring mechanical ventilation, miosis, hypothermia and bradycardia. The laboratory findings were hyperglycemia. The postmortem findings were pulmonary edema and congestion in the lungs and fatty changes in the liver. In this case report, we concluded that xylene aspiration was responsible for pulmonary edema and congestion in the lungs, and the aspiration pneumonitis rapidly led to septicemia which was the probable cause of death. This case was reported because of the limited information in the literature on this subject.
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    Burnout among High School Teachers in Turkey
    (Medi+World Int, 2005) Demirel, Yeltekin; Guler, Nuran; Toktamis, Aydin; Ozdemir, Deniz; Sezer, R. Erol
    Objective: The purpose of the present study was (a) to examine the burnout in a sample of Turkish high school teachers and (b) to test the hypothesis that Turkish teachers suffer from burnout more than the teachers in the developed countries. Methods: All of the high schools in the city Centrum of Sivas, Turkey were contacted for this study. Turkish version of the Maslach Burnout Inventory was used in this study. Six hundred and ten questionnaires were distributed to the teachers, and 520 questionnaires were returned. The 48 questionnaires were excluded in the final analysis, because of including inconclusive and/ or incomplete data. Result: There was no statistically significant difference between the scores of sub samples according (emotional exhaustion and depersonalisation) to the gender (p>0, 05). There was an insignificant negative correlation (p=0.08) between the depersonalisation and personal accomplishment in the group of female teachers. Drinking, smoking and marital status had no effect on burnout in this study sample (p>0.05). Less experienced Turkish teachers reported higher scores on depersonalisation (p=0.001). Conclusion: Turkish teachers suffer from burnout less that of the teachers in many developed countries.
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    Child Physical Abuse: A Five Case Report
    (Medi+World Int, 2006) Beyaztas, Fatma Yucel; Dokgoz, Halis; Oral, Resmiye; Demirel, Yeltekin
    [Abstract Not Available]
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    Combined Effect of Factor V Leiden, MTHFR, and Angiotensin-Converting Enzyme (Insertion/Deletion) Gene Mutations in Hypertensive Adult Individuals: A Population-Based Study from Sivas and Canakkale, Turkey
    (MARY ANN LIEBERT INC, 2011) Demirel, Yeltekin; Dogan, Sezai; Uludag, Ahmet; Silan, Coskun; Atik, Sinem; Silan, Fatma; Ozdemir, Ozturk
    Background: Hypertension is one of the leading causes of mortality and morbidity in the world, which is influenced by environmental and genetic factors. The methylenetetrahydrofolate reductase (MTHFR) and angiotensin-converting enzymes (ACE) are possible candidate genes that may influence both body fatness and blood pressure (BP). The purpose of this study was to examine the carriage of gene combinations of the ACE (insertion/deletion [I/D]), MTHFR 677T and 1298C, and lipid profiles in patients with essential hypertension (EH) in Turkey. Methods: A total of 150 adult individuals (50 hypertensive, 50 first-degree relatives, and 50 healthy controls) from Sivas/Turkey with the same age and gender were assessed for body composition, lipid profiles, resting BP, and gene profiles. Additionally, 149 individuals (99 hypertensive, 50 controls) from Canakkale/Turkey had been investigated for ACE I/D polymorphism. Peripheral blood samples were genotyped using strip assay reverse-hybridization multiplex polymerase chain reaction tests for target genes. Results: Heterozygous mutation in FV Leiden was found to be higher in the hypertensive and first-degree relatives when compared with the control group (p < 0.05). Homozygous DD alleles of the ACE gene were also higher than the ACE I/D and control groups (p < 0.05). The high rates of cholesterol and low-density lipoprotein and low rates of high-density lipoprotein were found in patients with EH when compared with the control. Conclusion: Results show that ACE with DD alleles and mutated alleles of FV Leiden and MTHFR genes were significantly different between genotypes and have a combined effect on EH in Turkish population. Further studies are needed to investigate the genetics of obesity, EH, and BP phenotypes in the current adult population.
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    Comparison of postoperative analgesia methods in lower abdominal surgery
    (Turkiye Klinikleri, 2006) Gürsoy, Sinan; Kaygusuz, Kenan; Demirel, Yeltekin; Duran, Bülent; Kafali, Haluk; Mimaro?lu, Caner
    Objective: The present study aimed to determine the advantage and disadvantage of different postoperative analgesia methods in patients undergoing cesarean section or hysterectomy under general anesthesia. Material and methods: Following ethics committee approval and patient informed consents, 120 patients were recruited from the ASA I-III groups. Patients were divided randomly into 6 groups. IM-D group received intramuscular diclofenac sodium (75 mg) every 12 hours. IM-ME group received intramuscular meperidine (1 mg kg -1) every 6 hours. IM-DME group received intramuscular meperidine (1 mg kg-1)-diclofenac sodium (75 mg) combination every 12 hours. EP-MO group received epidural morphine (bolus of 3 mg and 0.06 mg mL-1 morphine; 6 ml h-1) infusion. EP-MOB group received epidural infusion of morphine-bupivacaine combination (bolus of 2 mg morphine + 35 mg bupivacaine combination, 2 mg ml-1 bupivacaine + 0.03 mg mL-1 morphine combination; 6 ml h-1). IV-MO group received intravenous morphine via patient-controlled analgesia (loading dose of 3 mg, bolus of 1 mg and 20 minutes lockout interval). Heart rate, mean arterial pressure, SpO 2, pain and sedation levels were recorded at 2, 6, 12, 24 and 48 hours. Furthermore, additional analgesic consumption and side effects were also recorded. Results: Effective analgesia was in groups IM-DME, EP-MO, EP-MOB, and IV-MO. However, the lowest pain scores were obtained in groups EP-MO and EP-MOB. Sedation scores were higher in groups EP-MO and IV-MO. While the highest additional analgesic consumption was in groups IM-D and IM-ME, there was no additional analgesic consumption in groups EP-MO, EP-MOB and IV-MO. Side effects were not observed in any groups that required treatment. The highest incidence of side effects were in group IV-MO whereas the lowest incidence of side effects were observed in groups IM-DME and EP-MOB. Conclusion: While there was effective analgesia in groups IM-DME, EP-MO, EP-MOB, and IV-MO, IM diclofenac + meperidine combination and epidural bupivacaine + morphine combination seemed more advantageous when the side effects were considered. Copyright © 2006 by Türkiye Klinikleri.
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    Comparison of the effects of 70% alcohol, 10% povidone-iodine and 0.4% chlorhexidine which are used in umbilical care on colonization and umbilical cord separation time
    (ACADEMIC JOURNALS, 2012) Aydemir, Husniye; Alparslan, Ozgur; Demirel, Yeltekin
    This research has been designed and conducted as a randomized controlled trial to evaluate the effect of three regimens of cord care on cord separation time and umbilical cord colonization. Umbilical cord cares of 70% alcohol, 10% povidone-iodine and 0.4% chlorhexidine were applied to 40 term neonates who were randomly assigned (N = 120). Wipe samples were taken from babies just after the delivery and re-taken from umbilicus on the 5th day, and the separation time of umbilical cord was determined. The mean time to cord separation was significantly higher in the 70% alcohol group (7.10 +/- 1.61, p < 0.05). There were significant differences between the groups considering the culture results on the 5th day (p < 0.05); coagulase-negative staphylococci reproduced in a substantial part (27.5%) of the babies applied with 70% alcohol cares. Alcohol use delayed the time for cord separation compared to other methods. The authors concluded that 0.4% chlorhexidine may be effectively and safely used for umbilical cord care of healthy term neonates.
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    A comparison of the efficacy of varenicline and bupropion and an evaluation of the effect of the medications in the context of the smoking cessation programme
    (EUROPEAN PUBLISHING, 2017) Benli, Ali Ramazan; Erturhan, Selman; Oruc, Muhammet Ali; Kalpakci, Pinar; Sunay, Didem; Demirel, Yeltekin
    Background: Within the context of the support program for smoking cessation, initiated by the Turkish Ministry of Health in 2011, those who present at 'smoking cessation' centres and are found to be suitable for pharmacological treatment are given varenicline and bupropion free of charge. As the smoking cessation programme is centralized, the selection of the medication is made randomly to provide a fixed distribution rate. The aim of this study was to evaluate the efficacy of both varenicline and bupropion in smoking cessation and to evaluate the effect of the smoking cessation programme. Methods: A total of 405 individuals who met the study criteria were included in the study. Smoking habits and degree of dependence were determined in all the participants with the Fagerstrom test for nicotine dependence (FTND) and bupropion or varenicline therapy was initiated in those who were eligible. Patients were followed up at 15 days then at 1, 2, 3, 6 and 12 months after smoking cessation. A level of CO < 5 ppm and 'point prevalence abstinence' were used as the criteria of success for smoking cessation and this evaluation showed the non-smoking status in the previous 7 days. Results: The mean age of the participants was 35.19 +/- 7.73 years and 82.8% (n = 334) were male. Of the participants, 60.2% (n = 244) were given varenicline and 39.8% (n = 161) bupropion. The mean FTND and package/year was not significantly different between the groups. The rates of success in the 1st and 2nd weeks, and 1st, 3rd and 6th months were significantly higher in the varenicline group than in the bupropion group (p < 0.05). At the end of one year, the rate of smoking cessation was determined as 13.9% (n = 34) in the varenicline group and 6.2% (n = 10) in the bupropion gruop. The difference was statistically significant (p = 0.015). At the end of 1 year when the previous 7 days smoking status was evaluated with the 'point prevalence abstinence' measurement as the success criteria, success rates were 20.5% with varenicline and 18.6% with bupropion and the difference was not significant (p = 0.646). The individuals who used the medications for 45 days or longer were more successful in smoking cessation (p < 0.001). The most common reasons given for discontinuing the medication were the side-effects (31.5%). No significant difference was determined between the groups in respect of the side-effects observed. Conclusions: Although the rates of smoking cessation in all the other control points were higher with varenicline than with bupropion, no significant difference was found between the success rates of varenicline and bupropion used in smoking cessation based on the last 7 days at the end of one year. Those who used the medications for 45 days or longer were more successful in smoking cessation.
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    Correlation Between Serum Glucose/Potassium Ratio and The Severity of Mushroom Poisoning at The Time of Admission to The Emergency Departments
    (Sivas Cumhuriyet University, 2022) Tekin, Yusuf; Demirtaş, Erdal; Korkmaz, İlhan; Demirel, Yeltekin; Tekin, Gülaçan; Nur, Naim
    Exposure to wild mushrooms can lead to serious toxicity and death. It is accepted that patients who ingest potentially lethal mushrooms typically develop toxicity signs after six hours. However, clinical manifestations of poisoning that occur less than six hours after ingestion do not exclude the potential for life-threatening toxicity, especially when more than one type of mushroom has been eaten. Whereas there are not any clinical parameters that help to establish the severity of mushroom poisoning. In this study, we aimed to determine the relationship of serum glucose/potassium ratio and the clinical severity of mushroom poisoning cases.This is a retrospective study which includes the mushroom poisoning 510 cases between the years 2007 - 2018. Data consisted of age, gender, clinical history of mushroom poisoning including time from consumption to first symptoms, date of presentation, discharge time and laboratory results including complete blood cell count, biochemistry tests for liver and renal function, and coagulation profile. Patients included in this study were classified as mild-moderate and severe mushroom poisoning groups according to laboratory and clinical characteristics. Glucose, BUN, Creatinine, ALT, AST mean values and glucose/potassium ratio were significantly higher in the clinically severe group patients (p=0.008, p=0.01, p=0.039, p=0.037, p=0.046 and p=0.036 respectively). The sensitivity, specificity and area under curve for glucose/potassium ratio were as follows; 0.68, 0.57 (AUC %95CI) was 0.0647. Glucose/potassium ratio can predict the severity in mushroom poisonings according to our results which can helpful by management in mushroom poisonings as a laboratory result.
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    Differences in the body composition and biochemistry in women grouped as normal-weight, overweight and obese according to body mass index and their relation with cardiometabolic risk
    (VERSITA, 2010) Ozenoglu, Aliye; Ugurlu, Serdal; Can, Gunay; Sarkis, Cihat; Demirel, Yeltekin
    Morbidity of obesity-related diseases tends to increase due to a rise in the body mass index (BMI). We aimed to investigate how the body composition and biochemical parameters change while BMI increases in adult women were categorized as so: as normal weight, overweight and obese. Our objectives are to study the effects of those changes in the development of metabolic disturbances and to find out which parameters are the most sensitive to predict cardiometabolic risks. Three hundred and twenty two records of adult women (mean age: 38.62 +/- 12.71 year) who admitted to our unit concerning about losing or preserving their weights, were analyzed in the study. All patients had undergone anthropometric measurements and body composition analyses as well as some biochemical tests. Body composition analyses were performed by means of the Bioelectrical Impedance Analyzer (BIA). Increase in BMI significantly increased the body fat, blood sugar, insulin, triglyceride and uric acid levels. BMI and circumference of the waist were significantly and negatively correlated with the ratio of body water and lean mass/fat mass. However they were positively correlated with the ratio of fat mass and basal metabolism. Furthermore, it was also found that BMI and circumference of the waist were significantly and positively correlated with level of fasting blood sugar, insulin, triglyceride, homeostasis model assessment insulin resistance (HOMA-IR), uric acid and fibrinogen levels, and negatively correlated with high density lipoprotein (HDL) cholesterol level. In multiple regression analyses, circumference of waist measurements was significantly correlated with insulin, triglyseride and HDL, whereas the correlation between BMI and these parameters was not found significant. Total body fat mass (as %) showed significant correlation only with HDL-C level. It could be said that obesity which is a disorder that causes many health complications and affects the quality of life in the short and long term could be prevented or cured by keeping negative environmental conditions under control. According to our results, visceral adipose tissue (VAT) measurement was thought to be more related for metabolic and cardiovascular disorders rather than BMI. We also propose to test fasting blood glucose, insulin, triglyceride, HDL, fibrinogen, homocystein (HOM) levels along with VAT measurements to predict more truly about not only global cardiometabolic risk but also dementia in later life.
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    Epidemiological evaluation of burns
    (2002) Demirel, Yeltekin; Aydin, Cengiz; Kunt, Nur; Gökgöz, Şehsuvar
    Burns and related injuries are important health problems in our country due to shortage of the special burn centers. Scalding and flame-related injuries are the most common mechanism of thermal injury. Males and children dominate the incidence of burn injury. Epidemiological studies demonstrate that loneliness and cigarettes smoking are major predisposing factors, preferentially involves low socioeconomic population and large proportion of burns are home related. Burn size of 1-10 % of body surface area and higher rate of upper extremity involvement are seen. While small burns are treated on an outpatient basis, major ones require hospitalization. Severe cases must be referred to special burn centers.
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    Evaluation of the effects of serum bilirubin levels on intimal medial hyperplasia of carotis vessels
    (Aves, 2005) Demirel, Yeltekin; Tas, Aysenur; Tas, Fikret; Bolayir, Ertugrul; Topaktas, Suat
    Purpose: To investigate whether there is an independent effect of serum total bilirubin level on carotid atherosclerosis. Material and Metods: A total number of 145 subjects was used in this case-control type study. While 75 of the subjects had intimal medial hyperplasia in their carotid arteries, 70 of subjects served as the control group who had the same risk factors without intimal medial hyperplasia. Intimal medial hyperplasia was used as a dependent variable whereas hypertension, diabetes, high cholesterol levels, smoking and serum bilirubin levels were used as independent variables. Results: There were no differences between groups when age and sex were compared. Low total bilirubin level was found to be a risk factor for intimal medial hyperplasia as a result of logistic regression analysis [OR: 1.57, confidential limit 95% (1.16-1.93)]. On the other hand, hypertension (OR: 0.28, CI 95 %) and, hypercholesterolemia (OR: 0.31, CI 95 %) were found to be risk factors for intimal medial hyperplasia. Diabetes (OR: 1.38, CI 95 %) and smoking (OR: 0.90, CI 95 %) were not found as risk factors for intimal medial hyperplasia. Conclusion: Low serum total bilirubin level could be suggested as a risk factor for carotid intimal medial hyperplasia.
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    IN A FAMILIAL MEDITERRANEAN FEVER PREVALENT REGION, ARE FAMILIAL MEDITERRANEAN FEVER AND BEHCET'S DISEASE ASSOCIATED?
    (BMJ PUBLISHING GROUP, 2019) Alparslan, Ozgur; Egeli, Bugra Han; Demirel, Yeltekin; Ugurlu, Serdal
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    In vivo evaluation of the genotoxic effects of clomiphene citrate on rat reticulocytes: A micronucleus genotoxicity
    (KARGER, 2006) Duran, Bulent; Ozdemir, Ismail; Demirel, Yeltekin; Ozdemir, Ozturk; Cetin, Ali; Guven, Aysel
    Objective: To determine the genotoxic effects of clomiphene citrate (CC) on rat reticulocytes in vivo. Methods: In this prospective, randomized, controlled study, rats were each assigned randomly to the CC 50, CC 100, CC 200, or control group and were given repeat doses of 0.16, 0.32 or 0.64 mg CC, or normal saline, respectively. Each study group received its CC dose in 2 ml of saline intraperitoneally for 5 days, while the control group received only 2 ml of saline. Each treatment cycle was repeated six times. Six months later, the rats were euthanized. Bone marrow tissues were removed, and pluripotent reticulocyte cells with micronuclei, nuclear buds, and binuclear abnormalities were analyzed using an in situ micronuclei assay under light microscopy. The proportion of micronucleated erythrocytes was measured. Results: Fewer cells with nuclear buds and binuclear abnormalities were detected in the CC 50 group and controls. The CC 100 and 200 groups had significantly (p < 0.05) more nuclear buds and binuclear abnormalities compared with the CC 50 group and controls in the cytogenetic analysis of bone marrow stem cells. Conclusion: In rats, the micronucleus genotoxicity assay suggests a dose-dependent CC effect on genomic instability in bone marrow stem cells in vivo. Copyright (c) 2006 S. Karger AG, Basel.
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    MUSHROOM POISONING: RETROSPECTIVE ANALYSIS OF 294 CASES
    (HOSPITAL CLINICAS, UNIV SAO PAULO, 2010) Eren, Sevki Hakan; Demirel, Yeltekin; Ugurlu, Serdal; Korkmaz, Ilhan; Aktas, Can; Kukul Guven, Fatma Mutlu
    OBJECTIVE: The objective of this study was to present special clinical and laboratory features of 294 cases of mushroom poisoning. MATERIALS AND METHODS: In this retrospective study, 294 patients admitted to the Pediatric and Adult Emergency, Internal Medicine and ICU Departments of Cumhuriyet University Hospital were investigated. RESULTS: Of 294 patients between the ages of 3 and 72 (28.97 +/- 19.32), 173 were female, 121 were male and 90 were under the age of 16 years. One hundred seventy-three patients (58.8%) had consumed the mushrooms in the early summer. The onset of mushroom toxicity symptoms was divided into early (within 6 h after ingestion) and delayed (6 h to 20 d). Two hundred eighty-eight patients (97.9%) and six (2.1%) patients had early and delayed toxicity symptoms, respectively. The onset of symptoms was within two hours for 101 patients (34.3%). The most common first-noticed symptoms were in the gastrointestinal system. The patients were discharged within one to ten days. Three patients suffering from poisoning caused by wild mushrooms died from fulminant hepatic failure. CONCLUSION: Education of the public about the consumption of mushrooms and education of health personnel working in health centers regarding early treatment and transfer to hospitals with appropriate facilities are important for decreasing the mortality.
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    Nokturnal enuresis
    (2006) Toktamiş, Aydin; Demirel, Yeltekin; Özkan, K. U?ur
    Nocturnal enuresis (NE) is defined as a complete or near complete micturition in the bed during the sleep. The pathophysiology of NE is still not fully understood. A conceptual model has been proposed for understanding. The remarkable fact is that the great majority of children sleep dry for 8-9 hours or more while sometimes finding it hard to wait for only a couple of hours during daytime. Thus, nocturnal dryness requires functions that are not present during daytime. The basic pathophysiology of NE is simple in that the bladder gets filled to capacity during sleep and needs to be emptied. However, the child not wakes up. If he/she wakes up, he/she walks to the bathroom and performs the socially acceptable act of nocturia. If he/she does not wake up, the socially unacceptable bedwetting ensues. For the management of a child with NE, the most important diagnostic procedure is to identify monosymptomatic enuresis by history and physical examination. Once the history and physical examination has classified the child as monosymptomatic only minimal additional diagnostic work is needed. Daywetting is the most important symptom to exclude in order to classify the enuresis as monosymptomatic. If there is any amount of daytime incontinence present, the enuresis is definitely not monosymptomatic. A dip stick will exclude protein, glucos, hematuria and most urinary pathogens. If there is a history of previous urinary infections, urinary culture should be added. Management of NE is based on 4 principles: (1) Verify the child's motivation to be treated. (2) Information and instruction about daily habits underlining the importance of having regular fluid intake and voidings and relaxed routines at bedtime. (3) Enuresis alarm (4) Antidiuretic medication.
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    Prevalance of asthma and allergic diseases in Mid-Anatolia
    (2012) Arslan, Sulhattin; U?urlu, Serdal; Demirel, Yeltekin; Can, Günay
    Objective: Allergic diseases are commonly seen in childhood. In this study the prevalences of asthma and other allergic diseases were investigated among the school children in Sivas in the year 2008. Material and Method: The questionnaire was based on the "International Study of Asthma and Allergies in Childhood (ISAAC)" questionnaires. If children were younger than 12 years the questionnaire was distributed to children by their teachers at school and was filled out by their parents. Results: Mean age of 1947 children was 10.28±2.24 (7-16), 50.9%of them were girls and 49.1%were boys. Lifetime wheezing rate was 26.8%, physician-diagnosed asthma was 10.1%, allergic rhinitis was 25.2%, and allergic dermatitis was %28.3. The asthmatic subjects also reported the symptoms of allergic rhinitis (4.7%), conjunctivitis (4.2%) and dermatitis (4.3%). Conclusion: We determined the prevalence of asthma and other allergic disease of primary school children between ages of 7-15 in Sivas. One should bare in mind that one or more allergic diseases such as rhinitis, dermatitis and conjunctivitis may be observed in a student with asthma depending on the relationship between those diseases.
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    PREVALANCE OF ASTHMA AND ALLERGIC DISEASES IN MID-ANATOLIA
    (NOBEL ILAC, 2012) Arslan, Sulhattin; Ugurlu, Serdal; Demirel, Yeltekin; Can, Gunay
    Objective: Allergic diseases are commonly seen in childhood. In this study the prevalences of asthma and other allergic diseases were investigated among the school children in Sivas in the year 2008. Material and Method: The questionnaire was based on the "International Study of Asthma and Allergies in Childhood (ISAAC)" questionnaires. If children were younger than 12 years the questionnaire was distributed to children by their teachers at school and was filled out by their parents. Results: Mean age of 1947 children was 10.28 +/- 2.24 (7-16), 50.9%of them were girls and 49.1%were boys. lifetime wheezing rate was 26.8%, physician-diagnosed asthma was 10.1%, allergic rhinitis was 25.2%, and allergic dermatitis was %28.3. The asthmatic subjects also reported the symptoms of allergic rhinitis (4.7%), conjunctivitis (4.2%) and dermatitis (4.3%). Conclusion: We determined the prevalence of asthma and other allergic disease of primary school children between ages of 7-15 in Sivas. One should bare in mind that one or more allergic diseases such as rhinitis, dermatitis and conjunctivitis may be observed in a student with asthma depending on the relationship between those diseases.
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    Prevalence and associated factors of day wetting and combined day and night wetting
    (Karger, 2008) Toktamis, Aydin; Demirel, Yeltekin; Ozkan, Keramettin Ugur; Garipardic, Mesut; Gozukucuk, Ali; Nur, Naim
    Background: This study was conducted to determine the prevalence of diurnal enuresis ( DE) and its association with background variables among children aged 5-15 years living in Sivas and Kahramanmaras, Turkey. Methods: The parents of 1,760 children voluntarily completed a questionnaire consisting of 42 items under supervision of a researcher. Results: Overall, the reported prevalence of DE was 4.2%, with a tendency to decrease with increasing age and with no difference between genders. Smoking during pregnancy, delayed initiation and dealing with the child by punishment in toilet training, urination frequency, urgency, soiling, arousal difficulty, urinary infection history, lower school performance, poor social adaptation, wetting history in the family, were all significantly prevalent among diurnal enuretics (p < 0.05). Socioeconomic or sociodemographic factors based on families and stressful life events were not associated with DE (p > 0.05). 63.9% of all parents reported some level of concern about the wetting problem and 51.7% of the diurnal enuretics had previously visited a physician. Conclusions: The prevalence of DE in our sample is not too different from the prevalence rates reported previously from Turkey and other countries. This type of enuresis seems to be more associated with an organic neurological or urological disorder than is nocturnal enuresis. Copyright (c) 2008 S. Karger AG, Basel.
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    Prevalence of autism spectrum disorder (ASD) in Sivas City Center and ASD awareness of healthcare professionals in family health centers
    (Cukurova Univ, Fac Medicine, 2021) Golbasi, Hatice; Demirel, Yeltekin; Karaca, Sanem Nemmezi; Cicek, Ayla Uzun; Sari, Seda Aybuke
    Purpose: The aim of this study was to determine the prevalence of autism spectrum disorder (ASD) in Sivas City Center and to investigate the ASD awareness of healthcare professionals working in Family Health Centers (FHC). Materials and Methods: The sample of the study consisted of 752 children aged between 18-72 months, 90 family physicians and 78 family health personnel (FHPs). The ASD Knowledge-Attitudes Scale and the ASD Awareness Questionnaire were administered to healthcare professionals. The Modified Checklist for Autism in Toddlers (M-CHAT) was applied to all of the children. Results: The mean scores of the ASD Knowledge-Attitude Scale and ASD Awareness Questionnaire of the family physicians were significantly higher than FHPs. The risk rate for ASD in screening was 6.25% (n=47), and the prevalence rate was 0.53%. Twenty of these children who were found to be at risk were evaluated by a child and adolescent psychiatrist. Of the 20 evaluated children, 7 were found to be normal, while 4 had a diagnosis of ASD, and 9 had other psychiatric diagnoses. Conclusion: This study showed that the prevalence rate of ASD in Sivas City Center is 0.53% and that the ASD awareness of family physicians is higher than that of FHPs. We believe that training programs to increase the awareness of healthcare professionals about ASD can contribute to the early detection of children with ASD.
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    PREVALENCE OF FMF AND CHRONIC RENAL FAILURE DUE TO AMYLOIDOSIS AND FREQUENCY OF MEFV MUTATIONS IN ZARA, TURKEY
    (OXFORD UNIV PRESS, 2011) Ozdogan, Huri; Ugurlu, Serdal; Hatemi, Gulen; Demirel, Yeltekin; Calli, Sanda; Ozgon, Gulay; Yildirim, Suleyman; Batumlu, Mine; Cevirgen, Dilsen; Akyayla, Elif; Celik, Selda; Masatlioglu, Seval; Ozguler, Yesim; Cengiz, Mahir; Kilic, Hasan; Alpaslan, Ozgur; Balli, Mustafa
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