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    A Scale Development Study: Gynecologic Cancer Prevention Information Scale
    (Marmara Univ, Inst Health Sciences, 2021) Bekar, Mine; Demirel, Gulbahtiyar; Evcili, Funda; Doganer, Adem
    Objective: The aim of this study is to develop a valid and reliable measurement tool to determine the knowledge level of women about gynecologic cancer prevention. Methods: This study is of the methodological research type. The number of draft scale items in this study is 50. Women were taken to sample 10 times for each item (500 women) and pre-test was applied to 125 women which was 25% of the sample. The scale was re-applied to the first pre-test group after 3 weeks by test-retest method. The data were collected by using the Personal Information Form and Gynecologic Cancer Prevention Information Scale. The suitability of the data for factor analysis was investigated by the Kaiser-Meyer-Olkin coefficient and by Barlett's test of sphericity. In order to test the construct validity of the scale, exploratory and confirmatory factor analyses were performed. Results: Content validity index of the draft scale was 94%. Kaiser Meyer Olkin test value was 0.902 and the sample was found to be adequate and appropriate. On the other hand, the Bartlett test was obtained as chi(2)=9542.07 p<0.001 and it was accepted that the scale fulfilled the requirements for exploratory factor analysis. The scale took its final form and consisted of 35 items and 5 sub-dimensions as a result of the exploratory factor analysis and confirmatory factor analysis. Total percentage of variance explained of 5 factors was 66.53%. That the cronbach alpha coefficients of the scale have high coefficients of 0.82-0.95 and that the test-retest values have coefficients of 0.566-0.881 and the Cronbach's alpha coefficient of the scale was 0.951. Conclusion: The data obtained from this study reveal that scale is a valid and reliable measurement tool to determine the knowledge level of women about gynecologic cancer prevention.
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    Effects of acupuncture on pain and levels of IL-17 and IL-23 in the treatment of non-thermal endovenous ablation: A randomized clinical trial
    (Sage Publications Ltd, 2022) Orak, Yavuz; Eroglu, Erdinc; Baylan, Filiz Alkan; Yildiz, Sedat; Boran, Omer Faruk; Doganer, Adem; Altun, Ahmet
    Objectives Acupuncture is one of the oldest therapeutic interventions in the world for the treatment of pain, musculoskeletal diseases, and inflammation. This study aimed to investigate the effect of acupuncture on pain and IL-17 and IL-23 levels in the treatment of endovenous ablation. Methods The study was a randomized controlled trial. Patients were divided into group C (Control, n = 35) and group A (Acupuncture, n = 35). Group A patients were treated with acupuncture 24 h preoperatively. Follow-up checkups were conducted intraoperatively, postoperatively, and on the third day. Results There was no difference between men; there was a difference between women. Visual analog scale score was lower in group A at the intraoperative third and fifth minutes (0.00 vs. 1 and 0.00 vs. 0.5). Analgesic consumption was lower in group A at the end of third day (p = 0.024). Postoperative IL-17 levels were higher than preoperative levels in group A (23.58 vs. 19.33). Postoperative IL-23 levels were lower than preoperative levels in group A (13.66 vs. 29.51). Group C showed increased postoperative IL-23 levels (28.81 vs. 33.51). Preoperative IL-17 and postoperative IL-23 levels were lower in group A than in group C (19.33 vs. 27.69 and 13.66 vs. 33.51). Although no difference was observed between group A and group C in preoperative saphenous vein diameter, postoperative saphenous vein diameter was smaller in group A (p = 0.008). Saphenous vein diameter was smaller on day 3 in group A than in group C (p = 0.043). Conclusion Acupuncture is effective on acute pain and level of IL-23 in the treatment of endovenous ablation using cyanoacrylate.
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    Effects of Propofol versus Sevoflurane on Postoperative Pain and Neuroendocrine Stress Response in Oocyte Pickup Patients
    (Hindawi Ltd, 2021) Orak, Yavuz; Tolun, Fatma Inanc; Bakacak, Murat; Yaylali, Asli; Kiran, Hakan; oksuz, Hafize; Doganer, Adem
    Background. Pain aggravates the autonomic response to stress and raises neuroendocrine stress hormone levels. We compared the effects of propofol and sevoflurane on postoperative pain and neuroendocrine stress hormones. A prospective, randomized, and controlled trial was conducted with 60 patients. Methods. We randomly allocated patients to groups P (remifentanil/propofol, n = 30) and S (remifentanil/sevoflurane, n = 30). Preoperative blood samples were taken to measure serum adrenocorticotropic hormone (ACTH), corticotropin-releasing hormone (CRH), glucagon, cortisol, aldosterone, and prostaglandin E2 (PGE2) levels. Intraoperatively and postoperatively, clinical parameters were monitored at different time points. The hormone levels were again measured in the follicular fluid and blood postoperatively. Result. Demographic data were similar. The preoperative serum aldosterone levels were significantly higher in group P (p=0.001). Preoperative and postoperative serum ACTH, glucagon, cortisol, and PGE2 levels were significantly different in group P (p=0.009, p=0.004, p=0.029, and p=0.002); serum ACTH, glucagon, and PGE2 levels increased while serum cortisol levels decreased postoperatively. In group S, serum CRH and aldosterone levels, both increased in the postoperative period compared to the preoperative (p=0.001, p=0.006). Postoperatively, glucagon and PGE2 levels were both higher in group P than group S (p=0.019, p=0.015). In postoperative follicular fluid, glucagon and PGE2 levels were higher in group P, while cortisol levels were higher in group S (p=0.001, p=0.007, and p=0.001). Conclusion. The effects of anesthetic agents were different. In group P, in the preoperative and postoperative evaluation, ACTH, glucagon, and PGE2 increased postoperatively, while cortisol decreased. In group S, aldosterone and CRH increased postoperatively. Glucagon and PG E2 were higher in group P than S, postoperatively.
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    Effects of traditional practices in the postpartum period on postpartum depression
    (TAYLOR & FRANCIS INC, 2018) Demirel, Gulbahtiyar; Egri, Gamze; Yesildag, Birnur; Doganer, Adem
    In this descriptive study, our aim was to assess the effects of traditional practices on postpartum depression. The participants were 461 Muslim mothers with infants aged between 2 weeks and 12 months, without a history of postpartum depression or other psychiatric problems and capable of communicating fluently. The participants were volunteers and were recruited from family health centers in urban Turkey between January 15 and April 15, 2015. Data were collected in a single face-to-face interview with each participant. Mothers in the research locality frequently have recourse to traditional practices in the postpartum period and the incidence of postpartum depression appears to be lower amongst those who use such practices.
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    Prediction of factors affecting cognitive performance in pregnant women using robust regression methods
    (Tehran University of Medical Sciences, 2021) Doganer, Adem; Tok, Abdullah; Demirel, Gulbahtiyar
    Introduction: This study compared the outcomes of cognitive function assessments between pregnant and non-pregnant women groups to demonstrate alterations occurring during pregnancy. Furthermore, we aimed to determine the factors acting on cognitive functions in pregnant women. Material and Methods:42 pregnant and 42 non-pregnant women were included in the study. In order to compare cognitive performances, Montreal Cognitive Assessment test was applied to women. Results: The assessed scores of cognitive functioning were significantly different between pregnant and non-pregnant women (p <0.001). The test value was obtained as 22.29±4.57 with pregnants and as 26.02±2.19 with non-pregnant womens. The cognitive measurements yielded lower scores in the pregnant women. A negative correlation was found between the progesterone hormone levels and cognitive scores (p = 0.025). Progesterone hormone, TSH hormone and age of the pregnant were found to be important among the factors affecting the cognitive performances in pregnants (p=0.04; p=0.001; p=0.033, respectively). Conclusion:Significant reductions in cognitive functions are observed in women during pregnancy. During pregnancy, in order to increase the cognitive level of women, hormonal values of pregnant women should be followed. © 2020 Tehran University of Medical Sciences. Published by Tehran University of Medical Sciences.
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    The Effect of Episiotomy Repair Simulation on the Anxiety and Self-Efficacy levels of Midwifery Students
    (Mashhad University of Medical Sciences, 2020) Demirel, Gulbahtiyar; Evcili, Funda; Kaya, Nurdan; Doganer, Adem
    Background & aim: The prevalence of episiotomy varies significantly between countries (9%-100%). During simulation-based training, the use of materials which are considerably similar to human tissues is critical for the long-term success of training while performing episiotomy on laboring women. This study was performed to determine the effects of episiotomy repair simulation on the anxiety and self-efficacy levels of midwifery students. Methods: This one-group, quasi-experimental study with a pretest-posttest design was conducted at the Midwifery Department of a State University in Turkey between March and April 2017. The participants included 73 junior students, who trained during March-April 2017 on the beef tongue model for episiotomy repair, following participation in a lecture in the classroom environment which included theoretical information about episiotomy. The data were collected using a student demographic questionnaire, the state anxiety inventory and the general selfefficacy scale. Data analysis was carried out using SPSS software (version 22.0) through McNemar's and Wilcoxon test. Results: There was a significant difference before and after the simulation process regarding the state anxiety scores (39 vs 43, P<0.000). Moreover, a significant difference was observed before and after the simulation in terms of the general self-efficacy scores (76 vs 67, P<0.000). In other words, the students' anxiety levels decreased followed by increasing levels of self-efficacy after simulation (P<0.05). Conclusion: A beef tongue episiotomy repair simulation training and application reduced the anxiety and increased the self-efficacy levels of the students. In light of these results, it is recommended to include the beef tongue episiotomy repair simulation into the pre-clinical practice in the midwifery curriculum. © 2019 Mashhad University of Medical Sciences. All rights reserved.