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Öğe Antimicrobial activity of the essential oil of Cyclotrichium niveum (Boiss.) Manden. Et Scheng(ACADEMIC JOURNALS, 2009) Alim, Ahmet; Goze, Ismihan; Cetin, Ali; Atas, Ahmet D.; Vural, Nilufer; Donmez, ErolThe present study was designed to examine in vitro antimicrobial and antifungal activities of the essential oil of Cyclotrichium niveum. The major constituents of the essential oil were determined as pulegone (50.46%) and iso-menthone (34.53%). The antimicrobial activity of the oil was also tested against gram-positive and -negative bacteria and fungus using a disc-diffusion method and the minimal inhibitory concentration (MIC) values. The oil showed remarkable antibacterial activity against Klebsiella pneumoniae and Staphylococcus aureus. The essential oil exhibited also, strong antifungal activity against Candida albicans.Öğe Chemical composition and in vitro antimicrobial activity of the essential oil of Origanum minutiflorum O Schwarz & PH Davis(WILEY, 2007) Vardar-Unlu, Gulhan; Unlu, Mehmet; Donmez, Erol; Vural, NiluferThe essential oil obtained by hydrodistillation from the aerial parts of Origanum minutiflorum 0 Schwarz & PH Davis, an endemic species in Turkey, was analysed for its antimicrobial activity in vitro. Gas chromatography/mass spectrometry analysis of the essential oil resulted in the identification of 34 constituents accounting for 961.5 mL L-1 of the oil, the major compounds present being carvacrol (793.4 mL L-1), p-cymene (32.6 mL L-1) and gamma-terpinene (21.4 mL L-1). The in vitro antimicrobial activity of the essential oil was investigated in order to evaluate its efficacy against 16 bacteria and two yeasts, using disc diffusion and minimum inhibitory concentration methods. The essential oil showed strong antimicrobial activity against all test micro-organisms except Pseudomonas aeruginosa. Its main components carvacrol and p-cymene were also assayed for their antimicrobial activities. Carvacrol exhibited comparable activity to the crude oil, proving it to be the main component responsible for the biological activity observed. This study demonstrates the in vitro antimicrobial activity of the essential oil of this endemic remedy against a wide spectrum of clinically important microorganisms, including pathogenic yeasts, being the first report on the anticandidal properties of the essential oil of O. minutiflorum. (c) 2006 Society of Chemical IndustryÖğe Chemical composition, antibacterial and antifungal activity of the essential oil of Thymbra spicata L. from Turkey(TAYLOR & FRANCIS LTD, 2009) Unlu, Mehmet; Vardar-Unlu, Guelhan; Vural, Niluefer; Donmez, Erol; Ozbas, Z. YesimThe composition of the essential oil from aerial parts of Thymbra spicata L. from Turkey was analysed by GC-MS and its in vitro antimicrobial activity was examined. GC-MS analysis of the essential oil resulted in the identification of twenty-three constituents, representing 97.04% of the oil. The major compounds detected in the essential oil were carvacrol (60.39%), -terpinene (12.95%), and p-cymene (9.61%). The in vitro efficacy of the essential oil against 21 bacteria and seven Candida species was examined using disc diffusion and minimum inhibitory concentration (MIC) methods. The essential oil demonstrated strong anti-microbial activity in a wide spectrum against most microorganisms, particularly the yeasts tested. This is the first report on the anticandidal properties of the essential oil of T. spicata. In conclusion, this study confirms that T. spicata essential oil could be considered as a natural antimicrobial source.Öğe Total Lipid Content and Fatty Acid Composition of Seeds of Some Wild Achillea Species(Springer, 2019) Zonuz, Nuray; Akpinar, Nukhet; Donmez, Erol; Zengin, Gokhan; Akpinar, Ali Emre; Akpinar, Mehmet Ali[Abstract Not Available]
