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Öğe Analysis of different type of transmigrant mandibular teeth(MEDICINA ORAL S L, 2011) Kara, Muhammed-Isa; Ay, Sinan; Aktan, Ali-Murat; Sener, Ismail; Bereket, Cihan; Ezirganli, Seref; Demirkol, MehmetObjective: Until recently, most reports about transmigration have documented that the canine is the only tooth which can migrate to the opposite side of the arch. The goal of the study was to define the transmigration of different types of teeth in people in various regions of Turkey. Study Design: A total of 112,873 panoramic radiographic files from seven different Turkish cities were inspected. The following data were evaluated according to age, gender, number of transmigrant teeth, localization, eruption status, side, unilaterally or bilaterally and associated pathology or dental abnormalities. Results: Of the 112,873 radiographs included in the study, 90 were seen to present as transmigrant in 87 patients, representing 0.079% of the sample. There were only two (0.0017 %) transmigrant lateral (TML) teeth and only three (0.0026%) transmigrant premolar (TMP) teeth encountered. The mean age at the time that the transmigrant mandibular teeth were identified was 29.9 years, with a range from 10 to 66 years. Out of the 87 cases, 51 were female and 36 were male, with a male: female ratio of 1: 1.41. Transmigrants were more commonly seen unilaterally (96.5%). The most frequent associated pathology was odontoma. Conclusions: Because early detection is vital to prevent complications and ensure more successful treatment, these extensive studies are crucial. In this extensive study, we indicated cases of transmigration of premolar and lateral teeth as a variant. Demographic variables and properties of all transmigrants (TM) were also presented.Öğe Characteristics of 351 supernumerary molar teeth in Turkish population(MEDICINA ORAL S L, 2012) Kara, Muhammed-Isa; Aktan, Ali-Murat; Ay, Sinan; Bereket, Cihan; Sener, Ismail; Bulbul, Mehmet; Ezirganli, Seref; Polat, Hidayet-BurakObjective: The aim of the present study was to evaluate the demographic profile of supernumerary molar (SM) teeth in people in various regions of Turkey. Study Design: A retrospective analysis was carried out on an initial sample of 104,902 subjects drawn from the ortopantographics files from 10 clinics in 7 Turkish cities with documentation of demographic data, the presence of SM teeth, their location, eruption, morphology, and position within the arch. In one region associated pathologies and treatments were also evaluated. Results: Three hundred fifty-one SMs were detected in 288 patients, constituting 0.33% of the study subjects, with a greater frequency in females (56.4%). SMs were found more frequently in the maxilla (87.7%) than in the mandible, and distomolars (62.9%) were more common than paramolars. The SMs encountered were mostly of conical shape (45.7%), impacted (81.1%), and in a vertical position (52.1). The 33% of SM teeth were related to impacted molar teeth. Conclusion: The most common complication involving these teeth was soft tissue irritation. Demographic data from such specific extensive studies are crucial for improved diagnosis of SM teeth. Early detection allows for measures against complications and more successful therapy.Öğe Effects of Ankaferd BloodStopper on bone healing in an ovariectomized osteoporotic rat model(SPANDIDOS PUBL LTD, 2017) Ezirganli, Seref; Kazancioglu, Hakki Oguz; Acar, Ahmet Huseyin; Ozdemir, Hakan; Kuzu, Emre; Inan, Deniz SahinBone defects resulting from oncological surgical resections, congenital facial anomalies, trauma or infection represent a significant and common clinical problem. The present study aimed to evaluate the effects of a commercially-available medicinal plant extract product, Ankaferd BloodStopper (ABS), on bone healing. The present study was performed on 24 female ovariectomized (OVX) rats. A defect on each rat calvarium was created using a trephine burr prior to the rats being divided into two groups. Defects were grafted with a gelatin sponge soaked with normal saline (control group) or plant extract (experimental group). Half of the animals were sacrificed after 2 weeks and the others after 4 weeks. In the control group, the defects were not filled with regenerated bone. By contrast, in the experimental group, all defect areas had an increased amount of regenerated bone and connective tissue. Osteoblastic activity appeared to be greater in the experimental group however, osteoclastic activity was observed to be higher in the control group. At 2 and 4 weeks, there was a significant difference in the amount of newly regenerated bone observed in the experimental group compared with the control group (P<0.05). Therefore, the results of the present study indicated that local ABS application had a positive effect on bone healing in the OVX rat model.Öğe The Effects of Nigella Sativa Seed Extract on Bone Healing in an Experimental Model(LIPPINCOTT WILLIAMS & WILKINS, 2016) Ezirganli, Seref; Kazancioglu, Hakki Oguz; Ozdemir, Hakan; Inan, Deniz Sahin; Tek, MustafaThe purpose of this study was to histologically evaluate the effects on bone healing of nigella sativa seed extract applied on calvarial defects in an ovariectomized rat model. The study included 32 female rats weighing 280 to 310g with an average age of 3 months. A defect was created with a trephine burr on each rat calvarium. The rats were divided into 2 groups (control and study) of 8 animals each. All the defects were grafted with a gelatin sponge mixed with normal saline. In the study group, nigella sativa seed extract was applied systemically using an oro-gastric tube. Half of the animals in each group were sacrificed after 2 weeks, and the others after 4 weeks. In the control groups, the defects were not completely filled with regenerated bone. Osteoblast cells were observed more in the study groups. A higher rate of osteoclasts was determined in the control groups. In addition, the nigella sativa group had a statistically greater amount of bone formation than the others group at both 2 weeks and 4 weeks (P<0.05). The systemic application of nigella sativa seed extract demonstrated incredibly positive effects on enhanced bone healing in this experimental osteoporotic model.Öğe Effects of platelet rich fibrin alone used with rigid titanium barrier(PERGAMON-ELSEVIER SCIENCE LTD, 2013) Ozdemir, Hakan; Ezirganli, Seref; Kara, M. Isa; Mihmanli, Ahmet; Baris, EmreObjective: Platelet-rich fibrin (PRF) is a platelet and leukocyte rich and platelet preparation that concentrates various growth factors and therefore has the potential to be used as regenerative treatment. The aim of study was to assess the effects of platelet rich fibrin (PRF) on bone augmentation when used in conjunction with titanium barrier a rabbit calvaria model. Study design: Twenty-four adult male New Zealand rabbits were used in this study. Two titanium barriers were fixed on each rabbit's calvarium. The rabbits were divided into four groups (group one is control and the other three groups are experimental) and each group contains 6 animals. PRF, anorganic bovine bone (ABB), and biphasic calcium phosphate (BCP) were used with titanium barriers in the experimental groups. Any materials were not used in the control group. Half of the animals were sacrificed after 1 month, and the rest were sacrificed after 3 months. Histomorphometric evaluation was carried out in order to compare new bone formation among the groups. Results: Significantly more new bone area was noted in the PRF alone group than in the control group, no statistically significant differences were found among PRF, BCP and ABB groups after 1 month. PRF and ABB also had superior effects in new bone formation area control to the BCP group after 3 months. Conclusion: PRF may offer the ease of use, simple handling, and enhanced delivery of growth factors during the bone augmentation procedures. When used in conjunction with the titanium barriers, PEP use can increase the quality of the newly formed bone and enhance the rate of bone formation due to the concentration of growth factors. (C) 2012 Elsevier Ltd. All rights reserved.Öğe Neoplasms of the salivary glands in a Turkish adult population(MEDICINA ORAL S L, 2010) Kara, Muhammed Isa; Goze, Fahrettin; Ezirganli, Seref; Polat, Serkan; Muderris, Suphi; Elagoz, SahendeObjective: This retrospective study aimed to investigate the types and distribution of neoplasm of salivary glands in a Turkish population. Study Design: The histological diagnosis records of the Department of Pathology at Cumhuriyet University were reevaluated for 125 patients who were treated for salivary gland tumors from 1987 to 2008. The neoplasms were analyzed for histological diagnosis, age, sex, and site. The histological diagnoses were analyzed according to the 2005 WHO classification. Results: A total of 125 primary salivary gland neoplasms, consisting of 95 (76%) benign and 30 (24%) malignant groups were recorded. The most common major and minor salivary gland sites were the parotid (61.6%) and palatal glands (9.6%), respectively. Pleomorphic adenoma was the most frequent benign tumor followed by Warthin's tumor. Among the malignant group, adenoid cystic carcinoma was the most prevalent. Age for all cases ranged from 16-80 years; mean age was 41.97 years, with a female to male ratio of 1:1.15. Conclusions: Although there were some discrepancies, the characteristics of salivary gland tumors of Turkish patients are in line with those of patients from other countries according to tumor type, tumor site distribution, and age and sex of patients.Öğe Prevalence of congenitally missing second premolars(Cumhuriyet University Faculty of Dentistry, 2010) Ezirganli, Seref; Hüseyin Koçger, H.; Ozer, Koray; Kirtay, Mustafa; Ün, EminPurpose: The purpose of this study was to evaluate the prevalence and distribution of congenitally missing second premolars according to gender and localization. Materials and Methods: This study was performed on panoramic radiographs and clinical records of 7753 patients (4573 females and 3180 males) who referred to Oral and Maxillofacial Surgery Department from January 2000 to December 2009. A total of 52 cases with congenitally missing second premolars were detected. The cases were evaluated according to gender, localization, unilateral or bilateral of occurrence, and anomaly. Results: 70 congenitally missing second premolars in 52 cases (13 males and 39 females) were found on 7753 radiographs. The prevalence of congenitally missing second premolars was found 3 times higher in females than in males, 4 times higher in mandible than in maxilla. A congenital anomaly was not determined. Conclusion: In this study, the prevalence of congenitally missing second premolars was found to be as 0.67%.Öğe Radiographic evaluation location of the mental foramen(Cumhuriyet University Faculty of Dentistry, 2010) Ezirganli, Seref; Özer, Koray; San, Fatih; Kirmali, Ömer; Isa Kara, M.Purpose: The accurate location of mental foramen is important for surgery operation on mandible. The variations of its locations can be a cause of complication surgical operations such as especially implant surgery. The purpose of this study is to determine the location of mental foramen by analyzing digital panoramic radiographs of patients in Sivas. Materials and methods: In this study, 360 panoramic radiographs taken from patients were analyzed retrospectively. The different locations of mental foramen on panoramic radiographs were evaluated as symmetric and asymmetric considering gender. Additionally, the average distances of mental foramen to the alveolar ridge of the mandible and at the inferior border of the mandible were analyzed. Results: It was determined that mental foramen was located between the first and second premolars in 59.4% of patient and in line with the second premolar in 37.2%. It was found that mental foramen was between the first and second premolars in 64.6% of males and 55.1% female. It was determined that mental foramen was symmetrical in 80.28% of patient. It was determined its average distance, on the right side, at the alveolar ridge was of 16.79 mm and of the inferior border of the mandible was of 12.46 mm. It was also found that on the left side the average distance of foramen to the alveolar ridge is 16.80 mm and to the inferior border of the mandible is 12.58 mm. Conclusion: In conclusion, it was determined on panoramic radiography that mental foramen was the best location between the first and second premolars and its other locations were a few in Sivas. It was exhibited that mental foramen was bilaterally symmetrical on many of patient.Öğe The Prevalence of Impacted Premolars in the Anatolian Population(Aves, 2013) Ezirganli, Seref; Kirtay, Mustafa; Ozer, Koray; Un, Emin Celalettin; Kosger, Hasan Huseyin; Kazancioglu, Hakki OguzObjective: The aim of this study was to determine the prevalence of impacted premolars and the associated pathology of these teeth in the Anatolian population. Methods: This retrospective cohort study was composed of 10246 panoramic radiographs of patients (6074 females, 4172 males) between 2000 and 2011. We reviewed the panoramic radiographs and clinical data and determined the prevalence of impacted premolars to be associated with sex, age, and number of premolars. We investigated the associated pathology and approach of treatment. Results: A total of 83 patients (43 females, 40 males; mean age 23.42 +/- 11.18 years, range 12 to 69) had 101 impacted permanent premolars that were either mesioangular (n=47, 46.54%), vertical (n=32, 31.68% 9), distoangular (n=14, 13.86%), horizontal (n=6, 5.94%), and/ or buccolingual (n=2, 1.98%). Premolar transmigration was absent. Of these premolars, 7 (6.93%) were associated with cystic lesions. In this study, 61.39% of impacted premolars were extracted; 39 (38.61%) were followed up. Conclusion: The prevalence of impacted premolars in the Anatolian population was determined to be 0.98%. Although premolar impaction is infrequent, early diagnosis is important because most of the cases (93.07%) are asymptomatic.
