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    Alp Kayağı Antrenmanlarının Oksidatif Stres ve Antioksidan Düzeylerine Etkisi
    (Hasan ŞAHAN, 2024) Demiryürek, Duran; Polat, Metin; Gunturk, Inayet; Yazıcı, Cevat
    Bu çalışmada alp kayakçılarının rutin olarak gerçekleştirdikleri tek bir birim slalom ve büyük slalom antrenmanları süresince oluşabilecek olan oksidan ve antioksidan seviyelerinin total oksidan seviye (TOS) ve total antioksidan seviye (TAS) ölçümleri ile incelenmesi planlandı. Çalışmaya, uluslararası alp disiplini yarışmaları deneyimine sahip, 18-29 yaş aralığında 18 erkek sporcu gönüllü olarak katıldı. İlk olarak gönüllülerin vücut ağırlığı, boy uzunluğu, beden kitle indeksi ve MaxVO2 değerleri tespit edildi. Daha sonra, gönüllülere uluslararası standartlara uygun olan yarışma pistinde, beş gün arayla 2.5 saat süren büyük slalom ve slalom antrenmanları uygulandı. Her iki antrenman uygulaması öncesinde ve sonrasında gönüllülerden venöz kan örnekleri alınarak TOS ve TAS değerleri tespit edildi. Hem slalom hem de büyük slalom sonrasında TOS değerlerinde anlamlı bir değişim gözlenmezken, TAS değerlerinde anlamlı bir artış tespit edildi (p
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    ANGIOGENIC REGULATORS DURING ALPINE SKIING TRAINING
    (Dokuz Eylul Univ Inst Health Sciences, 2024) Polat, Metin; Gunturk, Inayet; Demiryurek, Duran
    Purpose: The present study evaluates angiogenesis response through the determination of acute changes in hypoxia inducible factor 1 alpha, vascular endothelial growth factor, erythropoietin and endostatin levels measured after a single-session slalom and giant slalom trainings. Material and Methods: A total of 20 volunteer male athletes average age of 22.16 +/- 4.86 years with no health problems, and with international alpine skiing competition experience were included in the study. At the outset, the height, body weight and VO2max values of the volunteers was measured, and a giant slalom training lasting 2.5 hours was performed after a week on a giant slalom course. The volunteers were then asked not to exercise for a week, and slalom training was performed lasting 2.5 hours on a slalom course. The endostatin, erythropoietin, hypoxia inducible factor 1 alpha, and vascular endothelial growth factor levels of the volunteers were examined from 5 ml venous blood samples drawn into biochemistry tubes 20 minutes before and as soon as trainings over both the giant slalom and slalom Results: A significant increase was determined in the hypoxia inducible factor 1 alpha, vascular endothelial growth factor, erythropoietin and endostatin levels after both the giant slalom and slalom Conclusion: These increases observed in the angiogenesis markers suggests that a single-session giant slalom and slalom trainings induces angiogenesis responses.
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    Increased hip circumference in individuals with metabolic syndrome affects serum nesfatin-1 levels
    (Bmj Publishing Group, 2020) Tekin, Tuba; Cicek, Betul; Konyaligil, Nurefsan; Gunturk, Inayet; Yazici, Cevat; Karaca, Zuleyha; Unlusavuran, Meltem
    Background This case-control study was conducted to investigate the relationship between serum nesfatin-1 levels and nutritional status and blood parameters in patients diagnosed with metabolic syndrome. Methods Thirty patients (case) diagnosed with metabolic syndrome according to National Cholesterol Education Program-Adult Treatment Panel III criteria were included. Thirty healthy subjects (control) matched with patients with metabolic syndrome in terms of age, gender and body mass index were included. Three-day food consumption records were obtained. Anthropometric indices were measured and body composition was determined by bioelectrical impedance method. Biochemical parameters and serum nesfatin-1 levels were measured after 8 hours of fasting. Results Serum nesfatin-1 levels were 0.245 +/- 0.272 ng/mL in the case group and 0.528 +/- 0.987 ng/mL in the control group (p>0.05). There was a positive significant correlation between serum nesfatin-1 levels and body weight, waist and hip circumferences in the case group (p<0.05). Each unit increase in hip circumference measurement affects the levels of nesfatin by 0.014 times. In the control group, there was a positive significant correlation between body weight and serum nesfatin-1 levels (p<0.05). A significant correlation was detected between HbA1c and serum nesfatin-1 levels in the case group (p<0.05). A significant relationship was detected between dietary fibre intake and the serum nesfatin-1 levels in the case group (p<0.05). Conclusions Anthropometric indices and blood parameters were correlated with serum nesfatin-1 levels in patients with metabolic syndrome. More clinical trials may be performed to establish the relationship between serum nesfatin-1 levels and nutritional status.