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Öğe Association Between Familial Mediterranean Fever and Cachexia in Females(Turkish League Against Rheumatism, 2020) Durmaz, Yunus; Ilhanli, Ilker; Cengiz, Ahmet Kivanc; Kaptanoglu, Ece; Ozkan Hasbek, Zekiye; Hizmetli, SamiObjectives: This study aims to investigate the association between familial Mediterranean fever (FMF) and cachexia in females. Patients and methods: The study included 32 female FMF patients (median age 27.50 years; range, 18 to 50 years) and 30 female healthy controls (median age 32 years; range, 18 to 50 years). Patients were classified according to Tel-Hashomer criteria. Circumference of arm, waist, and thigh was recorded. Short form 36 (SF-36) and Multidimensional Assessment of Fatigue (MAF) scale were applied. Composition of the body was measured with dual X-ray absorption. Muscle strength was measured with an isokinetic dynamometer, and strength of hand grip was measured from dominant hand with a hand dynamometer. C-reactive protein, erythrocyte sedimentation rate, fibrinogen and serum creatinine kinase (CK) levels were recorded. Results: Body mass index was significantly higher in controls. Twelve patients and one control had cachexia. CK level was significantly higher in patients than controls. Mass of muscle without fat was significantly higher in patients than controls. Peak torque values of extension and flexion at the velocity of 60 degrees/second [Newton meter (Nm)], and value of total work during extension at the velocity of 240 degrees/second (Nm) in isokinetic measures were significantly higher in controls. MAF score was significantly higher in patients with cachexia than patients without cachexia where the subscale scores of SF-36, except the vitality score, were significantly lower in patients with cachexia. However, Tel-Hashomer score was significantly higher in patients with cachexia. Conclusion: This study pointed at a significant association between cachexia and FMF in females. Muscle endurance was not affected in FMF patients with cachexia; however, decreased muscle strength, impaired quality of life and increased fatigue were observed in these patients.Öğe Prevalence of juvenile fibromyalgia syndrome in an urban population of Turkish adolescents: impact on depressive symptoms, quality of life and school performance(CHINESE MEDICAL ASSOC, 2013) Durmaz, Yunus; Alayli, Gamze; Canbaz, Sevgi; Zahiroglu, Yeliz; Bilgici, Ayhan; Ilhanli, Ilker; Kuru, OmerBackground Juvenile Fibromyalgia Syndrome (JFMS) is a chronic health condition characterized by widespread musculoskeletal pain and multiple tender points (TP). The objective of this study was to determine the prevalence of JFMS in the urban population of Samsun and to determine the impact of JFMS on depression symptoms, school performance and quality of life (QOL). Methods A cross-sectional study was conducted in 1109 children (mean age (14.8+/-2.0) years old). A questionnaire was applied to the children and a medical examination including TP was performed. Yunus and Masi's criteria were used for diagnosis of JFMS. The children with JFMS were compared with an age and sex matched non-JFMS group. Depression was assessed with Children's Depression Inventory (CDI) and QOL was evaluated with Pediatric Quality of Life Inventory 4.0 (PedsQL4.0). Results Sixty-one (5.5%) (13 boys and 48 girls) of 1109 children met the diagnostic criteria of JFMS. While PedsQL scores of children with JFMS were lower than the non-JFMS group for physical, emotional, social, school functioning and total score (P=0.001), CDI total score was higher in the JFMS group than in the non-JFMS group (P=0.001). The JFMS group reported more school absences (P=0.001) and the average school grade was lower in the JFMS group than in the non-JFMS group (P=0.03). Conclusion The prevalence of JFMS is high in school age children. Since JFMS is a common problem of childhood, early diagnosis and identification of the disorder and more comprehensive and successful treatment approaches with appropriate psychological assistance may prevent more complex and severe problems in adulthood.Öğe QUALITY OF LIFE, DEPRESSION, FATIGUE AND CO-EXISTING FIBROMYALGIA IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER(OXFORD UNIV PRESS, 2011) Cengiz, Kivanc; Ilhanli, Ilker; Durmus, Dilek; Alayli, Gamze…
