Yazar "Ipek, Irem" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    Biocompatibility of different resin composites after polymerization with two light curing units: an immunohistochemical study
    (Istanbul Univ Press, Istanbul Univ Rectorate, 2023) Ipek, Irem; Unal, Murat; Koc, Tulay
    Purpose The aim of this study is to compare the biocompatibility of two different resin composites after polymerization under two different light sources in three different time periods. Materials and Methods 72 polyethylene tubes polymerized with 2 different resin composites and 2 different light sources (Elipar S10 and Valo ) [Group 1: Kalore Elipar S10 (KE), Group 2: Kalore Valo (KV), Group 3: Essentia Elipar S10 (EE), Group 4: Essentia Valo (EV)] were implanted in the dorsal connective tissue of 18 rats. 24 empty polyethylene tubes [Group 5: (Control group)] were implanted in the dorsal connective tissue of 6 rats. Then, the rats were sacrificed after 7th, 15th and 30th days in each time intervals (n=8). Biopsy samples were stained with H&E and examined for inflammation, necrosis, macrophage infiltrate, giant cell and fibrous capsule criteria. Immunohistochemical staining was performed to evaluate proinflammatory cytokines (IL-1 beta, IL-6 and IL-8). Results When the composite groups and the control groups were compared; there was difference statistically significant for the criteria of inflammation at 7th and 15th days, there was no statistical difference between the time points in terms of fibrous capsule and necrosis. When the composite groups and control groups were evaluated in terms of proinflammatory cytokines; statistically significant differences were found at 7th, 15th and 30th days. Conclusion All CRs used in this study showed acceptable biocompatibility in the subcutaneous tissues of rats after polymerization with different light sources.
  • Küçük Resim Yok
    Öğe
    In-vivo Biocompatibility Evaluation of Different Self-Adhering Composite Resins on Wister Rats
    (Technical Assoc Photopolymers,Japan, 2021) Saygin, Aysegul; Unal, Murat; Koc, Tulay; Ipek, Irem; Candan, Merve
    This study aimed to compare the biocompatibility of two different self-adhering flowable resin composites (SAFCs). 54 polyethylene tubes filled with two different SAFCs [Group V: Vertise Flow (VF), Group F: Fusio Liquid Dentin (FLD), or Group C: empty (Control)] were implanted into the subcutaneous tissue of 18 rats. After 7, 30, and 90 days of implantation, the rats were euthanatized (n=6). The implanted materials were removed with the surrounding tissue for histologic evaluation. The subjects were evaluated in terms of inflammation, fibrous capsule thickness, necrosis, macrophage, and giant cell presence. When the SAFC groups and Group C were compared on days 7, 30, and 90, inflammation, fibrous capsule thickness, and macrophage on the 7th day were statistically significant (p<0.05). Statistically, the giant cell and macrophage criteria were statistically significant on the 7th, 30th, and 90th days in all groups (p<0.05). When the groups were evaluated on different days among themselves, significant differences were observed in terms of local tissue response (p<0.05), while necrosis was found to be statistically insignificant (p>0.05). Biocompatibility was found similar for the SAFCs. These materials used in the study have shown good biocompatibility in rats, and SAFCs can be considered suitable for all restorative treatments.
  • Küçük Resim Yok
    Öğe
    Push-out bond strength of Biodentine, MTA repair HP, and a new pre-mixed NeoPutty bioactive cement: scanning electron microscopy energy dispersive X-ray spectroscopy analysis
    (Springer, 2022) Ipek, Irem; Unal, Murat; Guner, Aylin; Candan, Merve
    The aim of this research was to evaluate the push-out bond strengths (PBSs) of three different calcium silicate-based cements abbreviated as Group 1 (NeoPutty), Group 2 (Biodentine), and Group 3 (MTA Repair HP). 15 root slices of 1 +/- 0.1-mm thickness were obtained from the middle triad of the roots of 5 maxillary premolar teeth. In each slice, three canal-like cavities parallel to the root canal were created for the experimental groups (n = 15). After endodontic irrigation, Group 1: NeoPutty, Group 2: Biodentine, and Group 3: MTA Repair HP were placed to the cavities, randomly. After the PBS test, all samples were examined scanning electron microscope (SEM) to determine failure patterns. To evaluate the chemical composition of the materials, three samples, one from each group, were prepared. Samples were prepared using plexiglass molds of 10-mm diameter and 2-mm thickness. The materials were then examined by an energy-dispersive X-ray spectroscopy (EDX, Inca, Oxford Inst.) for surface element analysis. The values obtained from tests were evaluated statistically significant (p < 0.05). After the PBS test, while there was no statistically significant difference between NeoPutty and MTA Repair HP, there was a difference with Biodentine. Based on the findings from this study, it was concluded that Biodentine has the highest PBS values.