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Öğe Ailevi Akdeniz ateşi’nde subklinik ateroskleroz ve okside LDL(Cumhuriyet Üniversitesi, 2010) Karaca, Sanem Nemmezi; Demirel, YeltekinAİLEVİ AKDENİZ ATEŞİ'NDE SUBKLİNİK ATEROSKLEROZ VE OKSİDE LDLÖğe Assesment Of Hpv Dna Positive Individuals In Sivas Province In Terms Of Some Variables(Sivas Cumhuriyet University, 2022) Karaca, Sanem Nemmezi; Yıldız, ÇağlarBackground: Cervical cancer is one of the most common cancers in women and causes death. Revealing the distribution of HPV prevalence and types in cervical cancer remains important for both treatment and vaccination strategies. The goal of this study is to determine the HPV DNA subtypes of women who are positive for Human Papilloma Virus (HPV) screening, and to evaluate their sociodemographic characteristics and cervical smear results. Methods: The study was conducted on 215 women who were directed to Sivas Cumhuriyet University Obstetry and Gynecology outpatient clinic by her gynecologists or family physicians between 2015-2018 years. A questionnary containing datas of patients about age, education levels and jobs of both spouses, smoking status, obstetric history and age of first sexual intercourse was filled out by the researcher. The data were analysed with SPSS (vers 23.0) program and significance level was taken as 0.05.Results: The most prevalent HPV types were type 16 and category of the others; with the rates of respectively 47% (n: 101), 40% (n: 86). The frequencies of ASCUS (undetermined atypical squamous epithelial cells), LGSIL (low-grade squamous intraepithelial lesion) and HGSIL (high-grade squamous intraepithelial lesion) were respectively found to be 7.9% (n: 17), 23.7% (n: 51) and 1.9% (n: 4). The relationship between HPV types and Pap Smear results was statistically significant (p: 0.011). There was no difference between patients and their spouses about education levels and occupations; and among patients on smoking status, menstrual patterns, age at first sexual intercourse and family planning methods and HPV types (p> 0.05). In women above aged 55, only two types of HPV DNA were observed; which were type 16 and category of the others (p: 0.005). The relationship between abortion history and HPV types was found out to be significant (p: 0.016). Conclusion: This study has contributed to the literature by revealing the types of HPV which observed in Sivas province over a period of 3 years.Öğe Bir Tıp Fakültesi Birinci Sınıf Öğrencilerinin Fakülteyi Seçme Nedenleri, Akreditasyonla İlgili Düşünceleri ve Akademik Başarı Düzeyleri(Tıp Eğitimini Geliştirme Derneği, 2021) Çetinkaya, Selma; Karaca, Sanem Nemmezi; Karagöz, NaimAmaç: Çalışmamız öğrencilerimizin fakülteyi seçme nedenlerini araştırmak, akreditasyonla ilgili düşüncelerini belirlemek ve akademik başarı düzeylerini saptamak amacıyla yapılmıştır.Yöntem: Tanımlayıcı tipte olan bu araştırmanın evrenini, 2016–2017 eğitim öğretim yılında birinci sınıfta okumakta olan 234 öğrenci oluşturmaktadır. Çalışmaya toplamda 172 öğrenci katılmıştır. Veriler gönüllülük esaslı olarak anket yöntemiyle toplanmıştır. Verilerin analizinde SPSS 22.0 programından yararlanılmış, tanımlayıcı istatistiklerin yanı sıra kikare ve t-testleri kullanılmıştır.Bulgular: Çalışmaya toplam 172 (%73,5) öğrenci katılmış olup; katılımcıların %49,4’ü erkek, %50,6’sı kadındır. Grubun yaş ortalaması 19,3±1,3’tür. Öğrencilerin mezun oldukları okullara bakıldığında ilk üç sırada %45,0 ile Anadolu Lisesi, %35,1 ile Fen Lisesi ve %8,8 ile özel lise yer almaktadır. Öğrencilerin %92,4’ü ilk tercih olarak tıp fakültesini seçerken, %90,0’ı isteyerek tercih yapmıştır. İlk tercih nedenleri olarak %85,3 “Gelecekte toplumumuza yararlı bir insan olmak istediğim için”, %75,7 “Manevi haz vereceğini düşündüğüm için” ve %65,1 “İnsanları sevmem ve onlara yardım etmek istediğim için” seçenekleri işaretlenmiştir. Öğrencilerin %16,3’ü fakülteye başladıktan sonra pişman olmuş, %15,8’i tekrar seçme şansı verilse tıp fakültesini seçmeyeceklerini ifade etmiştir. Cinsiyet açısından pişmanlık yaşayanlar arasında fark yokken, tekrar seçmeyecekler arasında erkekler istatistiksel olarak anlamlı seviyede çoğunlukta saptanmıştır (p=0.008). Öğrencilere tıp fakültesi dışında ikinci tercihleri sorulduğunda %45,0’ı diş hekimliği, %25,0’ı mühendislik, %23,8’i diğer, %3,1’i öğretmenlik ve %2,5’i eczacılık olarak ifade etmiştir. Öğrencilerin %59,6'sı akreditasyonun ne olduğunu bildiğini, %63,5'i tıp fakültelerinin akredite olup olmadığına baktığını, %60,5'i fakültemizin akreditasyonunu kontrol ettiğini ve %47'si fakültemizi tercih ettiğinde akredite olmasının önemli olduğunu belirtmiştir. Akademik başarıları göz önüne alındığında, isteyerek gelen öğrencilerin ders kurulu ortalamasının istemeyerek gelenlerden istatistiksel olarak anlamlı derecede yüksek olduğu bulunmuştur (p=0.027).Sonuç: Tıp fakültesine isteyerek gelen öğrencilerin, mesleki bilgi ve tecrübelerini artırmak için daha fazla emek sarf ettiği gözlenmektedir.Öğe Can Nomophobia be a Contemporary and Novel Cluster of Symptoms of Adult Separation Anxiety Disorder?(Duzce Univ, Fac Medicine, 2024) Yilmaz, Yavuz; Cicek, Ayla Uzun; Abanoz, Elif; Karaca, Sanem NemmeziObjective: The connection between adult separation anxiety disorder (ASAD) and nomophobia has been poorly investigated. The aim of this study is to evaluate whether there is a relationship between ASAD and nomophobia. Method: The sample consisted of 68 university students diagnosed with ASAD and 77 university students without ASAD. All participants were evaluated by a structured clinical interview, Adult Separation Anxiety Questionnaire (ASA), Separation Anxiety Symptom Inventory (SASI), Nomophobia Questionnaire (NMP-Q), Aand Smartphone Addiction Scale-Short Version (SAS-SV). Results: Participants with ASAD had longer daily phone usage times and had a higher frequency of checking the phone during the day and the rates of carrying a charger than controls. Compared to the control group, participants with ASAD had significantly higher ASA, SASI, NMP-Q, and SAS-SV scores and more severe nomophobia levels. The ASA scores were significantly positively correlated with SASI, NMP-Q, and SASSV. Regarding predictors of nomophobia, ASA, SASI, and SAS-SV scores had a positive and significant effect on nomophobia, and predicted nomophobia. Conclusion: Our research adds to the body of knowledge on nomophobia by demonstrating that people with ASAD are susceptible to developing nomophobia. Clinicians should be aware of the association between ASAD and nomophobia, and nomophobia may be an important concept that should be considered in the therapy approach to patients with ASAD.Öğe Çocuklarda Primer Enürezis Nokturna ile Alerjik ve Solunumsal Hastalıkların Birlikteliği(Kahramanmaraş Sütçü İmam Üniversitesi, 2021) Aydın, Gamze; Karaca, Sanem Nemmezi; Sarı, Seda AybükeAmaç: Enürezis; çocukluk çağında alerjik hastalıklardan sonra en sık görülen kronik hastalık olup, ciddi psikososyal sorunlara yol açabilmektedir. Az sayıda çalışmada, alerjik hastalıklar ve uykuda solunum bozukluğu ile ilişkili olabileceğine dikkat çekilmiştir. Bu çalışmada; hastaneye başvuran enüretik çocuklarda, primer enürezis nokturna (PEN) ile alerjik hastalıklar ve uykuda solunum bozukluğu ilişkisinin araştırılması amaçlandı. Gereç ve yöntemler: Vaka kontrol tipinde dizayn edilen bu çalışmada, PEN tanısı ile hastaneye girişi yapılmış 150 çocuk vaka grubuna dahil edildi. Ardından aile hekimliği ile çocuk ve ergen ruh sağlığı ve hastalıkları polikliniklerine çeşitli nedenlerle başvuran ve herhangi bir üriner şikâyeti olmayan benzer yaştaki 150 çocuk kontrol grubu olarak alındı. International Study of Asthma and Allergies in Childhood (ISAAC), Uykuda Solunum Bozukluğu anketi ve sosyodemografik verileri sorgulayan veri toplama formu araştırmacı tarafından aileler ve çocuklarla yüz yüze görüşülerek dolduruldu. Veriler SPSS 22.0 programına yüklendi ve yanılma düzeyi 0.05 kabul edildi. Bulgular: Çalışmadaki çocukların %52.3’ü erkek, %47.7’si kızdı ve yaş ortalamaları 10.3 ± 3.3 yıldı. PEN’li olguların %28.0’ine astımın, %33.3’üne alerjik rinitin ve %18.7’sine uykuda solunum bozukluğunun eşlik ettiği saptandı. Enüretik olmayan çocuklarda bu oranlar daha seyrek olup sırasıyla %12, %16.7 ve %1.3 idi (pÖğe Determination of the frequency and the affecting factors of obesity in school age children and adolescents in a rural area in sivas province(Ankara Yildirim Beyazit University, 2019) Agadayi, Ezgi; Çelik, Nurullah; Çetinkaya, Selma; Karaca, Sanem NemmeziObjectives: Our aim was to investigate the prevalence of and the risk factors associated with obesity among adolescents and children between the ages of 6-18 years in a rural area in Sivas province in Turkey. Materials and Methods: The universe of our descriptive cross-sectional study was consisting of 485 students who educate in Sivas Akincilar district. The study was carried out on 1-8 June 2018 and was conducted in 449 students who accepted to participate and met the criteria of inclusion in the study. The height, weight, waist and hip circumference of the children whose family signed the ethical consent form were measured by researcher and the standardized questionnaire consisting of 24 questions was conveyed to the parents. It was used Olcay Neyzi standards (created by the data of the national study) and Centers for Disease Control and Prevention, CDC standards in order to evaluate the measurements. The data were uploaded SPSS program. Shapiro Wilk, Chi-square, Mann-Whitney U, Kruskal Wallis, Kappa, Pearson correlation and Roc analyzes were performed. The results were evaluated at 95% confidence interval and p<0.05 at significance level. Results: Of the participants, 45.21% were girls and 54.78% were boys. The ages of the students varied between 6-17 years and the mean age was 11.82 ± 0.13 years. According to the CDC standards, body mass index percentages were 3.34% weak, 75.50% normal, 13.80% overweight and 7.34% obese. 55.00% of the families of obese children and 87.80% of the families of overweight children thought that their children were in normal weight. When the children's weight and parents' weight assessment of their children were compared, a significant difference was found between both CDC and Olcay Neyzi standards (p<0.001(CDC); p<0.001(Olcay Neyzi)). The cut-off value of the students' waist-to-height ratio was calculated as 0.46 for our study (CDC sensitivity %86.4, specificity %78.1; Olcay Neyzi sensitivity %89.1; specificity %74.3). There was no significant difference between the weight of the children and playing with their phone/tablet before going to bed (p=0.191(Olcay Neyzi); p=0.331(CDC)). Conclusion: In conclusion, we found the prevalence of obesity was significantly increased also in rural areas and the awareness of families about their children's weight was low. We concluded that the family-oriented approach should be strengthened in the fight against childhood obesity and that the number of trainings for parents should be increased. © 2019 Ankara Yildirim Beyazit University. All rights reserved.Öğe Dissatisfaction with life and absence of leisure time activity: clues to overt depression and occult suicide risk in elderly individuals without significant disabling disease(Wiley, 2020) Yilmaz, Nuryil; Karaca, Sanem NemmeziBackground Depression is a major public health problem in all ages. Besides other chronic physical diseases, it is one of the most common psychiatric disorders observed in the elderly. In this study, it was aimed to determine the prevalence of depressive symptoms and related factors and to draw attention to occult suicide probability in elderly people without significant disabling disease. Methods Individuals aged 65 and over, who were randomly selected from a family healthcare centre, were enrolled into the study. Geriatric Depression Scale (GDS) was used to assess prevalence of depression and Suicide Probability Scale (SPS) for risk of suicide. Results There were 323 elderly (F/M: 150/173). Mean age was 73.3 +/- 6.1 years. The majority had chronic physical illnesses (77.7%). Mean GDS and SPS scores were 11.07 +/- 4.6 and 62.91 +/- 8.24, respectively. Prevalence of depression was 27.6%. In multivariable logistic regression analysis, living without a spouse (P = 0.047, Exp(B) = 1.744, 95% CI = 1.008-3.01), dissatisfaction with life (P < 0.001, Exp(B) = 5.327, 95% CI = 3.02-9.36) and having no leisure time activity (P = 0.047, Exp(B) = 1.846, 95% CI = 1.009-3.37) were found to be the independent predictors of presence of depression, as indicated by GDS. In logistic regression analysis, dissatisfaction with life (P < 0.001, Exp(B) = 2.631, 95% CI = 1.53-4.50) was found to be an independent predictor of high SPS scores. Conclusion In elderly individuals without overt disabling disease, dissatisfaction with life, absence of leisure time activities, and a life without a partner seem to significantly increase the likelihood of overt depression. On the other hand, there is occult increase in suicide risk in the presence of dissatisfaction with their lives in the elderly.Öğe Evaluation of sleep quality and related factors in pregnant women(Sivas Cumhuriyet University, 2022) Karaca, Sanem Nemmezi; Kurt, Begüm; Yıldız, ÇağlarObjective: Although the pregnancy period is a physiological process, it can disrupt the sleep pattern and quality with some changes it causes. In this study, it was aimed to determine sleep quality, affecting factors and sleep problems, if any, in pregnant women who applied to our outpatient clinic for follow-up.Materials and Methods: This study, which was designed in a descriptive style, was conducted on 256 pregnant women who applied to the outpatient clinic. The data form included personal information, factors affecting sleep quality, sleep problems and Pittsburg Sleep Quality Index. In addition to descriptive statistics, Mann-Whitney U and Kruskal Wallis tests were used to evaluate the data uploaded to the SPSS program. The error level was set to 0.05. Results: The mean age of the pregnant women was 28.55. It was observed that the mean total PUKI score was 6.27±3.94 (0-18) and the mean sleep duration was 7.5 hours (3-14). Sleep quality was poor in 49.6% of the pregnant women. It was found that the sleep quality of pregnant women was poor in younger than 35 years old (p=0.026), education level of high school and above (p=0.010), who has gender expectetion (p=0.041) and not socially supported (p=0.009). The median weight gain in the third trimester was higher in pregnant women with poor sleep quality (p=0.022). It was determined that musculoskeletal pain, discomfort, frequent urination, swelling in the feet, pain/cramp in the legs and burning in the stomach during pregnancy affected sleep quality negatively. In pregnant women with poor sleep quality; problems such as shortening of sleep duration, difficulty in falling asleep, frequent interruption of sleep, difficulty in falling asleep again, waking up tired in the morning and waking up too early involuntarily were observed more frequently.Conclusion: About half of the pregnant women have poor sleep quality; physical complaints are effective on sleep quality. Sleep quality should be evaluated in all pregnant women and recommendations should be made for sleep hygiene.Öğe INFLUENCE OF COVID-19 PANDEMIC ON SEXUAL LIFE:WHAT IS THE SITUATION IN AN URBAN REGION OFTURKEY?(2022) Kurt, Begüm; Karaca, Sanem NemmeziObjectives: It was aimed to evaluate the effect of the Covid-19 pandemic on couples' sexual life and to\rinvestigate whether any difficulties were faced in supplying the proper counseling in family planning.\rMaterials and Methods: Volunteers who attend to family medicine outpatient clinic were recruited in the\rstudy to complete a cross-sectional online survey. Participants were asked to sociodemographic\rcharacteristics, used family planning methods, difficulty in accessing the method, development of unplanned\rpregnancy, Covid infection of the spouses, and retrospectively report their sexual behavior frequency, desire,\rand relationship satisfaction during and before the pandemic. Then International Index of Erectile Function\r(IIEF), and the Female Sexual Function Index (FSFI) were administered.\rResults: A total of 195 volunteers whose mean age was 40±7.94 participated in the study. Difficulty in\raccessing family planning methods was 3.59%, and the unintended pregnancy rate was 57.14%. Sexual\rintercourse frequency was once a month or less for 17.95% and once a week or more for 67.18%. A decrease\rin sexual intercourse was observed in 33.33%. Erectile dysfunction was detected in 68.92%. Sexual dysfunction\rwas found in 52.07% of the women. The mean FSFI score was 23.77 ± 8.27, while the median IIEF score was\r60. The frequency of sexual intercourse, and change in sexual desire were not influenced by Covid-19\rpandemic.\rConclusion: Sexual life in both genders was not regressed, but access to methods and counseling about family\rplanning was negatively affected by Covid-19 pandemic. Moreover, unintended pregnancies were observed at\rhigher rates even in a highly educated population during the Covid-19 pandemic.Öğe Kırsal bir bölgede aile hekimliği polikliniğine başvuran yetişkinlerin ağız sağlığı konusunda bilgi ve davranışları(2018) Ağadayı, Ezgi; Aydın, Selma; Karaca, Sanem Nemmezi; Küçükceran, Hatice; Teker, BaharAmaç: Kırsal bir bölgede yetişkinlerin ağız sağlığı konusunda bilgi ve tutumlarının değerlendirilmesi amaçlanmıştır.İkincil amacımız ebeveynlerin, bu konuda çocuklarına eğitimverme durumlarının belirlenmesidir.Yöntem: Araştırmamız tanımlayıcı bir çalışmadır. Araştırmamıza Sivas Akıncılar İlçe Devlet Hastanesi, Aile HekimliğiPolikliniği’ ne 01 Ocak-01 Şubat 2018 tarihleri arasındabaşvuran ve çalışmaya katılmayı kabul eden 235 kişi dahil edilmiştir. Katılımcılara ağız sağlığı hakkında bilgi vedavranışlarını ölçen anket yüz yüze görüşülerek uygulanmıştır.18 yaş altı hastalar, soruları cevaplayabilecek bilişsel yetenekte olmayanlar ve dişsiz hastalar çalışmaya dahil edilmemiştir.Sayısal değerlerin Shapiro-Wilk testi ile normallik analiziyapılmıştır. Normal dışı dağılan verilerin karşılaştırılmasındaMann-Whitney U testi kullanılmıştır.Bulgular: Çalışmamıza katılan 235 katılımcının %64,3 (n=151)’ü kadın, %35,7 (n=84)’si erkektir. Yaş ortancaları 35,0(min:18-maks:79)’tir. Ankette bilgi ölçen 9 soruya verilendoğru cevap ortancası 5 (min:0-maks:9)’tir. Katılımcıların dişfırçalamaya başlama yaş ortancası 12 (min:3-maks:53) olarakbulunmuştur. Katılımcılarımızın %6,0 (n=14)’sı diş hekiminedüzenli giderken, %88,5 (n=208)’i şikayeti oldukça gittiğinibelirtmiştir. Katılımcıların 186’sının çocuğu vardı. Ebeveynlerin %60,2 (n=112)’si çocuklarına ağız sağlığı hakkındaeğitim vermiştir.Sonuç: Katılımcıların bilgi düzeylerinin düşük olduğu veağız sağlığı konusunda eğitim ihtiyaçlarının olduğu tespit edildi. Çocuğu olanların yarısından fazlasının çocuklarına bukonuda eğitim verdiği tespit edildi. Yetişkinlere yönelik verilecek ağız sağlığı eğitimlerinin hem kendi sağlıkları için hemde çocuklarına doğru bilgileri öğretmeleri açısından gerekliolduğunu düşünülmektedir.Öğe Pandemide birinci basamak bakış açısı İle Yaşlı İzlemi(Selen Medya Yayıncılık Tanıtım ve Organizasyon Hizmetleri, 2020) Karaca, Sanem NemmeziYaşanılan COVID-19 pandemisi ile insanlık tarihinin önemli bir dönemine şahitlik etmekteyiz. Şüphesiz bu süreç, hepimizi farklı seviyelerde etkilemektedir. Toplumun yaşlı bireyleri bu süreçten en fazla etkilenen gruplar arasındadır. Enfekte olma ve hastalığın ağır seyretme riskinin yaşlılarda daha yüksek olduğu gözlenmiştir. Devam eden çalışmalara rağmen, henüz virüse karşı etkin bir tedavi yöntemi veya koruyucu aşı bulunamamıştır. Bu nedenle hastalığa yakalanmamak, en etkin yol olarak görülmektedir. Virüse karşı korunmada bilinen en kritik yöntemler maske, sosyal mesafe ve hijyen önlemlerinin alınmasıdır. Dünya Sağlık Örgütüde pandemi ile ilgili tavsiyelerini Haziran 2020 tarihinde güncellemiştir. Buna göre; SARS-CoV-2'nin toplumda önemli ölçüde bulaştığı alanlarda ve sosyal mesafenin sağlanmasının zor olduğu kamusal ortamlarda maske takılmasının teşvik edilmesi önerilmiştir. Bu nedenle pandemide koruyucu hekimliğin önemi artmıştır. Bu durum aile hekimlerinin iş yüküve sorumluluklarının artmasına neden olmuştur. Geriatrik popülasyonun kendine özgükarakteristik özellikleri vardır. Polifarmasi önemli sorunlardan biridir. Enfeksiyon hastalıkları yaşamın bu döneminde atipik seyirlidir, mortalite ve morbidite oranları daha yüksektir. Kas kitlesi ve fonksiyonlarının kaybı ile seyreden sarkopeni, fiziksel engelliliğin artışına neden olmaktadır. Fiziksel aktivitenin azalması sarkopeni riskini artırmakta, bu da yaşam kalitesini azaltmaktadır. Bu nedenle geriatrik popülasyonda yaşanan değişikliklerin etkisi beklenenden daha fazla olabilmektedir. Bu yazıda pandemi sürecinde geriatrik bireylerin yaşadığı sorunlar ve kısıtlılıklar, fiziksel, psikolojik ve toplumsal yönleri ile ele alınmış; sistemdeki uygulamalar ve aile hekimliği bakış açısı ile imkanlar dahilinde yapılabilecekler özetlenmeye çalışılmıştır.Öğe Preparedness and Knowledge Level of Family Physicians Regarding Anaphylaxis Diagnosis and Management(2023) Serbes, Mahir; Karaca, Sanem NemmeziObjective: Anaphylaxis is under-recognized and undertreated by physicians, indicating critical knowledge gaps. This study aimed to assess the knowledge levels of anaphylaxis among family physicians (FPs) as they are the primary first-line healthcare providers and identify the factors influencing their knowledge levels. Materials and Methods: A cross-sectional study using an internet-based Google Forms questionnaire was conducted among voluntary FPs in Sivas, Turkey. Demographic features, including age, years in practice, and career position, and knowledge related to the diagnosis and management of anaphylaxis in children were assessed. Results: A total of 140 FPs participated in the survey (34 [24.3%] general practitioners [GPs], 20 [14.3%] contracted family physicians [CFPs], 74 [52.9%] residents in training [RITs], and 12 [8.6%] specialists). The number of participants who correctly answered all questions regarding diagnosis, acute treatment, and epinephrine auto-injector use was 11 (7.9%), 52 (37.4%), and 27 (19.3%), respectively. In diagnosing anaphylaxis, 100 (72.5%) participants were unaware that anaphylaxis can occur without skin manifestations, and only 48 (34.8%) identified gastrointestinal symptoms as a possible anaphylaxis presentation. RITs (11, 14.9%) and specialists (2, 16.7%) had better performance on the questionnaire, with higher proportions of participants who answered all questions correctly, compared to GPs (2, 5.9%) and CFPs (1, 5.0%). Attendance at an educational activity in the last year was the only independent factor associated with answering all questionnaire items correctly. Conclusion: There is a need to improve anaphylaxis recognition and management among all FPs regardless of their career position and work experience, underlining the importance of regular and updated educational interventionsÖğe Prevalence of autism spectrum disorder (ASD) in Sivas City Center and ASD awareness of healthcare professionals in family health centers(Cukurova Univ, Fac Medicine, 2021) Golbasi, Hatice; Demirel, Yeltekin; Karaca, Sanem Nemmezi; Cicek, Ayla Uzun; Sari, Seda AybukePurpose: The aim of this study was to determine the prevalence of autism spectrum disorder (ASD) in Sivas City Center and to investigate the ASD awareness of healthcare professionals working in Family Health Centers (FHC). Materials and Methods: The sample of the study consisted of 752 children aged between 18-72 months, 90 family physicians and 78 family health personnel (FHPs). The ASD Knowledge-Attitudes Scale and the ASD Awareness Questionnaire were administered to healthcare professionals. The Modified Checklist for Autism in Toddlers (M-CHAT) was applied to all of the children. Results: The mean scores of the ASD Knowledge-Attitude Scale and ASD Awareness Questionnaire of the family physicians were significantly higher than FHPs. The risk rate for ASD in screening was 6.25% (n=47), and the prevalence rate was 0.53%. Twenty of these children who were found to be at risk were evaluated by a child and adolescent psychiatrist. Of the 20 evaluated children, 7 were found to be normal, while 4 had a diagnosis of ASD, and 9 had other psychiatric diagnoses. Conclusion: This study showed that the prevalence rate of ASD in Sivas City Center is 0.53% and that the ASD awareness of family physicians is higher than that of FHPs. We believe that training programs to increase the awareness of healthcare professionals about ASD can contribute to the early detection of children with ASD.Öğe Prevalence of multiple sclerosis in an urban population of Sivas province in Turkey(TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2019) Gokce, Seyda Figul; Cigdem, Burhanettin; Karaca, Sanem Nemmezi; Bolayir, Asli; Yildiz, Ozlem Kayim; Topaktas, Ahmet Suat; Balaban, HaticeBackground/aim: Multiple sclerosis (MS) is a common neurological disorder that can be a leading cause of nontraumatic disability in several countries. Recent reports have indicated a moderate to high risk of MS in European countries. In this study, we examined the prevalence of MS in a well-defined urban population of provincial center in Sivas Province in Turkey. Materials and methods: This study sampled all registered residents of urban areas of provincial center in Sivas Province in April 2017 and 2018 January. All the included patients met the McDonald 2010 criteria. Medical records were reviewed, including all available previously acquired magnetic resonance imaging data. All patients were subsequently subjected to neurologic examination to confirm the MS diagnosis. Results: We identified 21 possible MS patients, with MS diagnosis confirmed in 19. The prevalence of MS was 288 per 100,000 inhabitants. Conclusion: For future studies, these high ratio results can be used in regional and national comparisons to determine cofactors contributing to the high prevalence of MS in our region and can help health-decision makers to better plan healthcare policies to improve neurological services and awareness about multifaceted clinical presentations of MS.Öğe Subclinical Atherosclerosis and Oxidized LDL Levels in Familial Mediterranean Fever(Sivas Cumhuriyet University, 2022) Uğurlu, Serdal; Karaca, Sanem Nemmezi; Demirel, Yeltekin; Seyahi, EmireObjective: To investigate markers of carotid atherosclerosis and oxidized low density lipoprotein (OxLDL) levels in patients with Familial Mediterranean Fever (FMF) who have no risk factors for cardiovascular disease.Method: It was included 44 patients (25 F/19 M; mean age: 33.5±7.5) with FMF in attack free period and gender and age matched 44 healthy subjects (25 F/19 M; mean age: 33.4±7.0). The patients with clinical coronary artery disease, chronic renal disease, diabetes mellitus, hypertension, history of myocardial infarction, angina pectoris, cerebrovascular disease, dyslipidemia, metabolic syndrome, active infection, those in postmenopausal period, and those using anti-lipid drugs were excluded. Carotid artery intima-media thickness (C-IMT) was measured and investigated atherosclerotic plaques in the carotids by using doppler ultrasound. Serum lipid and OxLDL levels were also assessed. Data were analyzed with the SPSS program and p<0.05 were accepted as significant.Result: Mean disease duration of the FMF patients was 20±9 years. The mean C-IMT did not differ between the patient and control groups (0.52±0.10 mm, 0.53±0.06 mm, respectively, p=0.709). None of the patients or controls had atherosclerotic plaques. Total and LDL cholesterol levels were significantly lower in the patient group compared to the controls (total cholesterol: 157.07±34.18, 181.05±36.79, respectively, p=0.002; LDL cholesterol: 100.48±30.13, 126.25±34.05, respectively, p=0.001). However, we found that OxLDL levels were significantly higher in FMF patients compared to control group (337.48±438.56 ng/dl, 156.19±383.24 ng/dl, p=0.044). No correlation was found between C-IMT and OxLDL levels in both patients (p=0.324) and controls (p=0.246).Conclusion: Our study provides further evidence for no increased atherosclerosis in FMF. As previously shown, FMF patients have lower cholesterol levels compared to healthy controls. On the other hand, increased OxLDL levels could be associated with increased subclinical inflammation.Öğe The importance of preoperative imaging methods in reduction mammoplasty(Elsevier Sci Ltd, 2022) Derebasinlioglu, Handa; Karaca, Sanem NemmeziBreast reduction surgery is a common procedure in plastic surgery clinics, and there are varying practices regarding preoperative mammography and breast ultrasound in patients who have no history of cancer and no symptoms other than those caused by macromastia. In this study, we retrospectively analyzed the imaging findings of patients who presented to the plastic surgery outpatient clinic due to macromastia between January 1, 2006 and June 1, 2020 and underwent mammography and/or breast ultrasound for preoperative screening and breast magnetic resonance imaging for further examination. Patients with a history of breast cancer diagnosed prior to preoperative screening or any other breast disease were excluded. Radiologically suspicious findings were significantly more common in patients over 40 years of age and significantly less frequent in the group under 50 years of age. When the patients were grouped by the decade of life, the frequency of radiologically suspicious findings was significantly lower in the 20-29 group and significantly higher in the 40-49 and 50-59 groups. Malignancy was not detected by histopathological examination in any patient. Proliferative lesions were detected in 10 reduction mammoplasty specimens (2.4%) of 7 patients (3.1%). The correlation between radiological and histopathological findings may be weak in macromastia patients. Most suspicious radiological findings appear to be the population between 40 and 59 years of age.(c) 2021 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.Öğe The Role of Inflammatory Markers in the Differential Diagnosis of Skin Cancers(Rabia YILMAZ, 2022) Derebaşınlıoğlu, Handan; Demir, Hande; Karaca, Sanem NemmeziAim: The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic immune-inflammation index (SII)
