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Öğe Acute retinal necrosis: clinical features, management and outcomes(Springer, 2023) Yalcinsoy, Kubra Ozdemir; Ozdal, Pinar Cakar; Tekin, Merve Inanc; Karatepe, Mustafa Salih; Erol, Yasemin OzdamarPurpose To evaluate the clinical features, treatment, and visual outcome of patients with acute retinal necrosis (ARN). Methods The data of patients were retrospectively reviewed. Factors associated with visual loss and factors affecting the risk for retinal detachment (RD) development were evaluated. Results Twenty-four eyes of 24 patients (7 female/17 male, mean age 43.7 years, mean follow-up period 31.0 months) were included. In ocular fluid samples of 15 (83%) out of 18 eyes, polymerase chain reaction (PCR) tests were positive for herpes simplex virus (seven eyes; 39%), varicella zoster virus (six eyes; 33%), cytomegalovirus (one eye; 6%), and adenovirus (one eye; 6%). Central retinal occlusive vasculitis was observed in three (13%) eyes. Systemic antiviral therapy was given to all patients, and additional intravitreal ganciclovir was administered in seven eyes (29%). The most common complication was RD (46%). There was no statistically significant difference in the frequency of RD between herpes simplex virus- and varicella zoster virus-positive patients (p = .617). The rate of RD was similar in eyes undergoing prophylactic laser photocoagulation (LPC), eyes undergoing vitrectomy + LPC, and eyes not undergoing LPC (p = .237). The number of eyes with final visual acuity below 20/200 was significantly higher in eyes with RD than without RD (p = .047). Conclusion Prophylactic LPC and vitrectomy did not show clear benefits in terms of preventing RD development. RD was the most common complication and a major factor for a poor visual prognosis.Öğe Development of posttraumatic stress disorder and depression after open globe injury in adults(Springer, 2023) Keles, Ali; Karayagmurlu, Ali; Yetkin, Esat; Sonmez, Kenan; Karatepe, Mustafa Salih; Karaman, Suleyman KorhanPurpose To investigate the prevalence of posttraumatic stress disorder (PTSD) and depression after open globe injury in adults. Methods A total of 95 participants, 43 adult patients with open globe injury and 52 age-sex similar subjects (control group), were included in this cross-sectional study. Age, gender, education level, occupation, accident history, psychiatric history, trauma type, cause of trauma, and visual acuity were recorded. One to six months after trauma, PTSD and depression symptoms of the participants were evaluated with the Posttraumatic Stress Disorder Questionnaire-Civil Version Scale (PTSD-S) and Beck Depression Inventory (BDI), respectively. Results Patients with open globe injury had a higher PTSD-S total score than the control group, but not significant (23.67 +/- 20.41 vs. 18.56 +/- 13.13, p = 0.580). Patients with eye trauma exhibited a much higher prevalence of PTSD compared to the control group (20.9% vs. 3.8%, p = 0.010). Patients with trauma had a significantly higher BDI total score than the control group (12.47 +/- 10.08 vs. 7.69 +/- 6.10, p = 0.015). Also, patients had a higher rate of depression symptoms than controls (25.6% vs. 7.7%, p = 0.017). A significant positive correlation was observed between PTSD-S and BDI scores in the trauma group (r = 0.720, p < 0.001). Conclusion An increased prevalence of PTSD and depression was observed in adults after open globe injury. The significant relationship between PTSD-S and BDI scores indicates that patients with open globe injuries should be questioned in terms of both symptoms. For patients with open globe trauma, a holistic approach with psychosocial assessment in addition to physical intervention would be beneficial.Öğe Evaluation of contrast sensitivity in patients with congenital red-green color vision deficiency(Springer, 2024) Karatepe, Mustafa Salih; Bozali, ErmanPurpose To evaluate mesopic and photopic contrast sensitivity in patients with congenital red-green color vision deficiency regarding with and without glare conditions and to compare these findings with age- and gender-matched healthy controls with normal color vision. Methods Patients with congenital red-green color vision deficiency and age- and gender-matched healthy controls were included in this cross-sectional comparative study. Contrast sensitivity measurements were taken from all subjects in 4 different conditions; binocular mesopic-without glare, mesopic-with glare, photopic-without glare, photopic-with glare, and the results were compared. Results Twenty one patients with color vision deficiency (13 deuteranopic, 8 protanopic) and 22 age- and gender-matched healthy controls were included in the study. The mean age was 35.2 +/- 13.5 years in the protan group, 30.6 +/- 7.7 years in the deutan group, 32.0 +/- 8.8 years in the control group, and there was no significant difference in age between the groups (P > 0.05). The mean mesopic and photopic contrast sensitivity values of the groups at all spatial frequencies (1.5, 3, 6, 12, 18 cpd) were not statistically significant when evaluated by the multifactor repeated measures test of ANOVA to evaluate the effect of light conditions (with and without glare) (P > .05). Conclusion Mesopic and photopic contrast sensitivity values of patients with congenital red-green color vision deficiency were similar to healthy controls regarding with and without glare conditions.Öğe Geriatrik Popülasyonda Göz Acilleri: 2015-2023 Tek Merkez Sonuçları(Duzce University, 2025) Karatepe, Mustafa Salih; Yeter, Duygu YalınbaşAmaç: Acil servise göz şikayetleri ile başvuran geriatrik hastaların klinik ve demografik özelliklerini değerlendirmek, risk faktörlerini belirlemek, uygun önleme stratejilerini tasarlamak ve mevcut olanların geliştirilmesini sağlamaktır. Gereç ve Yöntemler: Acil servise oftalmik şikayetlerle başvuran ≥ 65 yaş hastaların kayıtları geriye dönük olarak değerlendirildi. Hastalar başvuru şikayetlerine göre travmatik ve travmatik olmayan olarak iki gruba ayrıldı. Bulgular: Çalışmaya yaş ortancası 72 (65-100) olan iki yüz beş hasta dahil edildi. Hastaların 81'i (%39,51) ortanca yaşı 74 (65-100) olan kadın ve 124'ü (%60,48) ortanca yaşı 71,5 (65-93) olan erkeklerden oluşmaktaydı. Hastaların 124'ü (%60,48) travmaya bağlı nedenlerle, 81'i (%39,51) travmatik olmayan nedenlerle başvuruda bulundu. Travmaya bağlı nedenlerle başvuru yapan hastaların 25'i (%20,16) kadın, 99'u (%79,83) erkekti. Travma dışı nedenlerle başvuru yapan hastaların 56'sı (%69,13) kadın, 25'i (%30,86) erkekti. Travmaya bağlı nedenlerle başvuru yapan hastalarda en sık düşmeler (%24,19) izlendi. Cinsiyete göre göz travmaları, erkek hastalarda kadın hastalara göre istatistiksel olarak anlamlı bir şekilde daha sık izlendi (pÖğe Long-term Effects of Uncomplicated Traumatic Hyphema on Corneal and Lenticular Clarity(Korean Ophthalmological Society (KOS), 2022) Keles, Ali; Kosekahya, Pinar; Sogut, Furkan Emre; Karatepe, Mustafa SalihPurpose: To evaluate the long-term effects of uncomplicated traumatic hyphema on endothelial morphology, anterior segment structure, and corneal and lenticular densitometry Methods: In this retrospective comparative study, eyes with a history of uncomplicated traumatic hyphema were compared with the healthy contralateral unaffected eyes. The corneal endothelial cell properties were captured using specular microscopy. Anterior segment analysis, corneal densitometry (12-mm corneal diameter), and lens densitometry measurements were performed using the Pentacam imaging system. Results: Measurements were obtained at a mean follow-up of 49.5 ± 15.8 months after injury. The average endothelial cell density was significantly lower in the study group than in the control group (2,506.6 ± 294.0 cells/mm2 vs. 2,665.7 ± 195.0 cells/mm2, p = 0.020). There was no difference between the groups in respect of polymegathism and pleomorphism (p = 0.061 and p = 0.558, respectively). All the investigated corneal tomographic and angle parameters were similar in both groups (all p > 0.05). The corneal densitometry values in all concentric zones and layers showed no statistically significant difference between the groups (p > 0.05 for all). The lens zone 1 densitometry value was significantly higher in the study group than in the control group (9.6% ± 1.1% vs. 8.9% ± 1.2%, p = 0.031). No difference was observed in zone 2 and 3 (p = 0.170 and p = 0.322, respectively). The degree of hyphema was not correlated with endothelial cell and lenticular clarity loss (p = 0.087 and p = 0.294, respectively). Conclusions: Even if traumatic hyphema is not complicated, long-term outcomes indicate endothelial cell loss and increased lenticular density. © 2022 The Korean Ophthalmological Society.
