Yazar "Kazancioglu, Hakki Oguz" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    Effects of Ankaferd BloodStopper on bone healing in an ovariectomized osteoporotic rat model
    (SPANDIDOS PUBL LTD, 2017) Ezirganli, Seref; Kazancioglu, Hakki Oguz; Acar, Ahmet Huseyin; Ozdemir, Hakan; Kuzu, Emre; Inan, Deniz Sahin
    Bone defects resulting from oncological surgical resections, congenital facial anomalies, trauma or infection represent a significant and common clinical problem. The present study aimed to evaluate the effects of a commercially-available medicinal plant extract product, Ankaferd BloodStopper (ABS), on bone healing. The present study was performed on 24 female ovariectomized (OVX) rats. A defect on each rat calvarium was created using a trephine burr prior to the rats being divided into two groups. Defects were grafted with a gelatin sponge soaked with normal saline (control group) or plant extract (experimental group). Half of the animals were sacrificed after 2 weeks and the others after 4 weeks. In the control group, the defects were not filled with regenerated bone. By contrast, in the experimental group, all defect areas had an increased amount of regenerated bone and connective tissue. Osteoblastic activity appeared to be greater in the experimental group however, osteoclastic activity was observed to be higher in the control group. At 2 and 4 weeks, there was a significant difference in the amount of newly regenerated bone observed in the experimental group compared with the control group (P<0.05). Therefore, the results of the present study indicated that local ABS application had a positive effect on bone healing in the OVX rat model.
  • Küçük Resim Yok
    Öğe
    The Effects of Nigella Sativa Seed Extract on Bone Healing in an Experimental Model
    (LIPPINCOTT WILLIAMS & WILKINS, 2016) Ezirganli, Seref; Kazancioglu, Hakki Oguz; Ozdemir, Hakan; Inan, Deniz Sahin; Tek, Mustafa
    The purpose of this study was to histologically evaluate the effects on bone healing of nigella sativa seed extract applied on calvarial defects in an ovariectomized rat model. The study included 32 female rats weighing 280 to 310g with an average age of 3 months. A defect was created with a trephine burr on each rat calvarium. The rats were divided into 2 groups (control and study) of 8 animals each. All the defects were grafted with a gelatin sponge mixed with normal saline. In the study group, nigella sativa seed extract was applied systemically using an oro-gastric tube. Half of the animals in each group were sacrificed after 2 weeks, and the others after 4 weeks. In the control groups, the defects were not completely filled with regenerated bone. Osteoblast cells were observed more in the study groups. A higher rate of osteoclasts was determined in the control groups. In addition, the nigella sativa group had a statistically greater amount of bone formation than the others group at both 2 weeks and 4 weeks (P<0.05). The systemic application of nigella sativa seed extract demonstrated incredibly positive effects on enhanced bone healing in this experimental osteoporotic model.
  • Küçük Resim Yok
    Öğe
    The Prevalence of Impacted Premolars in the Anatolian Population
    (Aves, 2013) Ezirganli, Seref; Kirtay, Mustafa; Ozer, Koray; Un, Emin Celalettin; Kosger, Hasan Huseyin; Kazancioglu, Hakki Oguz
    Objective: The aim of this study was to determine the prevalence of impacted premolars and the associated pathology of these teeth in the Anatolian population. Methods: This retrospective cohort study was composed of 10246 panoramic radiographs of patients (6074 females, 4172 males) between 2000 and 2011. We reviewed the panoramic radiographs and clinical data and determined the prevalence of impacted premolars to be associated with sex, age, and number of premolars. We investigated the associated pathology and approach of treatment. Results: A total of 83 patients (43 females, 40 males; mean age 23.42 +/- 11.18 years, range 12 to 69) had 101 impacted permanent premolars that were either mesioangular (n=47, 46.54%), vertical (n=32, 31.68% 9), distoangular (n=14, 13.86%), horizontal (n=6, 5.94%), and/ or buccolingual (n=2, 1.98%). Premolar transmigration was absent. Of these premolars, 7 (6.93%) were associated with cystic lesions. In this study, 61.39% of impacted premolars were extracted; 39 (38.61%) were followed up. Conclusion: The prevalence of impacted premolars in the Anatolian population was determined to be 0.98%. Although premolar impaction is infrequent, early diagnosis is important because most of the cases (93.07%) are asymptomatic.