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Öğe Comparison of behavioral and hematological parameters before and after treatment in dogs with demodicosis(2022) Koçkaya, MustafaThis study aims to compare behavioral and hematological parameters of 12 dogs with demodectic mange infection before and after the treatment. Following the parasitological examination, an appropriate treatment protocol was planned for the dogs diagnosed with demodex canis. Blood samples were collected from the cephalic vein of the dogs and transferred into vacuum tubes containing EDTA before and after the treatment A complete blood count was performed for all dogs. Behavioral parameters before and after treatment were obtained with a video camera recording system. Compared to pretreatment values, WBC, Mon (%), Neu (%), MCHC, and Eos (%) values were significantly lower after treatment while Lymph (%), RBC, Hb, MCV, MCH values were significantly higher after treatment, and the difference between the values was found to be statistically significant (P<0.01). Behavior parameters related to stress were detected in fewer dogs after the treatment compared to pre-treatment. This study provided valuable inputs to the literature as the concurrent examination of blood parameters and stress behavior was performed for the first time in dogs with demodectic mange infection.Öğe Comparison of hemogram, amylase and lipase values in cats with feline panleukopenia disease and healthy cats(İstanbul Veteriner Hekimler Odası, 2024) Çelik, Bensu Cemre; Koçkaya, MustafaFeline panleukopenia (FPV), commonly known as the feline distemper virus, is a type of DNA virus. Known for its high transmissibility, FPV primarily affects young cats, particularly targeting the bone marrow, intestines, and lymphatic system. Without treatment, it can be fatal. The aim of this study is to compare the hemogram parameters of an infected cat with those of a healthy cat, and to facilitate diagnosis and prognosis by also comparing amylase and lipase levels. In the study, 30 cats were evaluated and divided into two groups: the control group and the patient group. The patient group consisted of 15 cats that tested positive for FPV using a rapid antigen test, while the control group consisted of 15 cats that tested negative for the antigen and showed no clinical symptoms. In the study, white blood cell, lymphocyte, neutrophil, neutrophil, monocyte, eosinophil, red blood cell and platelet counts, haematocrit and haemoglobin values were found lower in sick cats (p 0.05). Amylase and lipase values of sick cats were found to be higher than healthy cats (p 0,05). According to the study's results, white blood cell count, neutrophil, monocyte, lymphocyte counts, and platelet count were found to be highly reliable parameters for diagnosing fpv infection.Öğe Deafness risk estimation analysis of native genetic resource kangal shepherd dog breed: Sivas province example(Science Publications, 2019) Koçkaya, Mustafa; Özşensoy, Yusuf; Murat, HakanKangal shepherd dogs have excellent sensory organs and perform missions perfectly. For this reason, in many countries of the world, they are preferred for herd guard and as shepherd dog. One of these sensory organs is hearing. The aim of this study was to evaluate the deafness risk estimation analysis of Kangal shepherd dogs breeding in Sivas province of Turkey. The Brainstem Auditory Evoked Response test was applied to 160 Kangal shepherd dogs in Sivas province city center and districts. During the application, the dogs were kept in the present natural environment. The dogs were divided into groups according to their general, gender and age and their responses to frequencies ranging from 20, 40, 60 and 80 decibels (dB) for the right and left ears were investigated. One-Way ANOVA and Duncan multiple comparison test were used in the age group comparison and independent samples t-test was used in the comparison of the other groups. All statistical analysis were performed in the SPSS v.15 software. As a result, the presence of unilateral deafness was detected in 2 dogs in totally. It was also shown that the sense of hearing did not improve in puppies up to 11 days old. Group comparisons were provided statistical significance for right ear in 40 and 60 dB for age groups and right ear in 80 dB for gender groups (P<0.05). There was no difference in comparison of the other frequencies of the groups (P>0.05). This is the first study that deafness estimation was conducted in Kangal shepherd dogs. © 2019 Mustafa Koçkaya, Yusuf Özşensoy and Hakan Murat.Öğe Eff ect of Exercise on Electrocardiography and Stress Behavior of Kangal Shepherd Dogs with Ankyloglossia(2021) Koçkaya, MustafaEff ect of exercise has been studied on electrocardiography and stress behavioral parameters of 12 male Kangal shepherd dogs with ankyloglossia and 15 male Kangal shepherd dogs without ankyloglossia were compared. In this study, electrocardiography recordings were obtained from Kangal shepherd dogs with the holter device at resting state and during 15-min exercise. All data collection were conducted in the same environmental conditation. In addition, behavioral parameters captured with a video camera during resting state and the end of 15-min exercise period. While no statistical diff erence was detected in two groups in terms of all electrocardiographic parameters at resting state, statistical diff erences were detected in both groups in the P wave amplitude, T wave amplitude, duration of PR interval, duration of QT interval and heart rate parameters during exercise. Following 15-min of exercise, all stress parameters were observed in dogs with ankyloglossia, while only two parameters were observed at resting state. Following a 15-min exercise, without ankyloglossia dogs showed only two stress parameters, while no parameters were observed at resting state. This study will have an important area in the literature in terms of examining the electrocardiographic data and stress behavioral parameters of Kangal shepherd dogs with ankyloglossia.Öğe Effect of Exercise on Electrocardiography and Stress Behavior of Kangal Shepherd Dogs with Ankyloglossia(Kafkas Universitesi Veteriner Fakultesi Dergisi, 23.06.2021) Koçkaya, MustafaEff ect of exercise has been studied on electrocardiography and stress behavioral parameters of 12 male Kangal shepherd dogs with ankyloglossia and 15 male Kangal shepherd dogs without ankyloglossia were compared. In this study, electrocardiography recordings were obtained from Kangal shepherd dogs with the holter device at resting state and during 15-min exercise. All data collection were conducted in the same environmental conditation. In addition, behavioral parameters captured with a video camera during resting state and the end of 15-min exercise period. While no statistical diff erence was detected in two groups in terms of all electrocardiographic parameters at resting state, statistical diff erences were detected in both groups in the P wave amplitude, T wave amplitude, duration of PR interval, duration of QT interval and heart rate parameters during exercise. Following 15-min of exercise, all stress parameters were observed in dogs with ankyloglossia, while only two parameters were observed at resting state. Following a 15-min exercise, without ankyloglossia dogs showed only two stress parameters, while no parameters were observed at resting state. This study will have an important area in the literature in terms of examining the electrocardiographic data and stress behavioral parameters of Kangal shepherd dogs with ankyloglossia.Öğe Effects of transportation induced stress in electrocardiography data and blood parameters in Kangal Akkaraman sheep breed(Burdur Mehmet Akif Ersoy University, 2019) Koçkaya, MustafaThe objective was to investigate the stress effects induced by transportation in blood parameters and in electrocardiography data in Kangal Akkaraman sheep breed. Clinically healthy 36 Kangal Akkaraman sheep were used in the study. Electrocardiography data from the sheep were obtained by holder device during the resting period, and during 30 minute and 120 minute transportation periods. Blood parameters were determined from serum samples obtained during resting period, and after 30 minute and 120 minute transportations. Statistical evaluations were conducted by using Paired Samples t-Test. For each intergroup evaluation, significant differences were observed in the durations both PR to QT interval and P-wave, in the amplitude of P-wave, in heart pulse count per minute, and in glucose levels in serum samples. Significant differences were obtained for durations of both the QRS complex and T-wave in groups of resting and 30 min transportation, and of 30 min transportation and 120 min transportation. Significant differences were obtained for serum total protein, albumin, and creatinine levels in groups of resting and 120 min transportation, and 30 min transportation and 120 min transportation. No significant difference was obtained for serum blood urea nitrogen levels between study groups. This study is the first in literature where the effects of transportation induced stress in electrocardiography data and blood parameters in Kangal Akkaraman breed sheep were investigated.Öğe Investigation of Deafness in Dogs Found in Stray Animals Care and Rehabilitation Centre(Sivas Cumhuriyet Üniversitesi, 2024) Koçkaya, Mustafa; Özşensoy, Yusuf; Alıcı, ŞahinStray animals that have been domesticated by humans and found in the same environment and can establish social relationships with their own population and other living communities, especially humans, in nature and are ownerless. In this study, it was aimed to investigate the deafness of mongrel dogs in the Stray Animal Care and Rehabilitation Centre of Sivas Municipality. A total of 20 crossbred dogs in the Centre were examined for deafness with the Brainstem Auditory Evoked Response (BAER) test (20, 40, 60 and 80 decibels (dB)) and their hearing thresholds were obtained. Afterwards, the dogs were grouped as a single group without any discrimination according to general, and sex (male and female), whether the ear was cut or not, and age range (3 years old and under, and over 3 years old) and wave ranges of 20, 40, 60 and 80 dB of both ears in all groups, and the I-III-V. wave ranges of 80 dB in the general group were compared. In group comparisons, Mann Whitney U test was performed with SPSS v.25 package program since there were 2 groups in each group and the number was small. As a result of the study, 20 and 40 dB sound range could not be detected in 2 animals and 60 dB in 1 animal in the group over 3 years of age. As a result of the comparison of the groups, statistical significance was found in the 60 and 80 dB of left ear in the whether the ear was cut or not groups, and in all wavelengths of both ears in the age groups (PÖğe Maternal canibalism in all aspects(İstanbul Veteriner Hekimler Odası, 2023) Koçkaya, Mustafa; Demirbaş, Yasemin Salgırlı; Ercan, NazlıIn the present study, information is given about the diagnosis, treatment and prevalence of maternal cannibalism. In Sivas province, blood serum parameters, behavioral parameters and oxytocin hormone levels were compared of 15 clinically healthy female dogs with maternal cannibalism and 15 female dogs without maternal cannibalism. As a result of the data obtained, the cause was found of maternal canibalism. Treatment protocol has been developed. Afterbirth carbetosin administration was applied to 19 clinically healthy female dogs that was exhibiting maternal canibalism in Sivas province. Following the carbetosine administration, the mother's behavioral patterns towards the offspring, and the mother's electrocardiography data were examined. Every stage of the study, the dogs were not removed from their current habitat, and they were allowed to continue their usual routines. After the treatment protocol was developed, those who communicated with us via social media, e-mail and telephone with the complaint of maternal cannibalism by dog breeders and animal owners were recorded and the prevalence of the disease was determined. In the study, especially the serum oxytocin value was below the normal reference ranges in dogs with maternal canibalism. Dogs with maternal cannibalism in behavioral analyzes was display a more stressful and insecure body language. In the treatment, determined that the maternal canibalism behavior was not observed in Kangal shepherd dogs where carbetosin was applied, and that the dose of carbetosin application had no negative effect on heart parameters in mother dogs. When the communication records were examined, the prevalence was determined as 73 patients from different breeds in 11 months. Part of this work has been published previously.Öğe Normative data obtained in testing the sense of hearing in kangal shepherd dogs(Science Publications, 2019) Koçkaya, Mustafa; Özşensoy, Yusuf; Murat, HakanSense of hearing is of crucial importance for dogs to perform their duties. There is no study to determine the reference latency intervals of dogs’ sense of hearing. The aim of this study is to identify normative data that can be used as the reference interval for the wave latencies I, III and V at 80 dB with respect to the sense of hearing of Kangal shepherd dogs. The Brainstem Auditory Evoked Response test was applied to 106 Kangal shepherd dogs in Sivas province. The animals have been grouped by age, sex and general. Normative data were identified for the reference latency intervals for each wave of the right and left ears of the groups and statistical differences between the wave latency intervals were also examined. One-Way ANOVA and post-hoc Duncan test were used in the age group comparison and independent samples t-test was used in the comparison of the other groups. All statistical analyses were performed using the SPSS v.22 software. When the groups are compared, only statistically significant difference was found in the age group at the wave latency V at 80 dB HL. No statistically significance was found in all other groups. The average values of the wave latencies I, III and V were found to be 1.37-2.36-3.65 ms, 1.37-2.35-3.63 ms, 1.38-2.36- 3.68 ms, 1.35-2.37-3.79 ms, 1.30-2.26-3.57 ms and 1.41-2.39-3.59, general, female, male, 20 day -9 month, 10-30 month and 31 months and older, respectively. Since normative data on the sense of hearing of Kangal shepherd dogs have been identified for the first time with this study, it is expected to make a significant contribution to the literature. This normative data can be used as reference interval in clinical examinations and future studies on the sense of hearing of Kangal shepherd dogs. © 2019 Mustafa Koçkaya, Yusuf Özşensoy and Hakan Murat.Öğe Sivas İlinde Bulunan Aksaray Malaklısı Köpeklerinin Sağırlık Yönünden Araştırılması(Sivas Cumhuriyet University, 2022) Koçkaya, Mustafa; Özşensoy, Yusuf; Murat, HakanAksaray Malaklısı Türkiye’nin yerli genetik kaynaklarından olan bir köpek ırkıdır. Bu çalışmada Sivas ilinde yetiştirilen Aksaray Malaklısının duyma ve işitmesine yönelik mevcut durumun ortaya konulması amaçlanmıştır. Sivas il merkezi ve Kangal ilçesindeki 3 işletmede bulunan toplam 34 adet Aksaray Malaklısı çoban köpeğinde Brainstem Auditory Evoked Response (BAER) testi ile sağırlık tarama işlemi gerçekleştirilmiş ve 20, 40, 60 ve 80 desibeller (dB) yönünden duyma eşikleri elde edilmiştir. Daha sonra köpekler hiçbir ayrıma tabi tutulmadan tek grup olacak şekilde genel, cinsiyet, kulağı kesik olup olmaması ve yaş aralığına göre gruplandırılmış ve her iki kulağa ait dalga boyları yönünden karşılaştırılmaları da yapılmıştır. Grup karşılaştırılmalarında genel grubunda bağımsız gruplarda t-testi, cinsiyet ve kulağın kesik olup olmaması durumuna göre oluşturulan gruplarda Mann Whitney U testi ve yaş grubunda ise Kruskal-Wallis testi uygulanmıştır. Tüm istatistiksel analizler SPSS v.25 paket programında gerçekleştirilmiştir. Çalışma sonucunda, toplam 2 hayvanda tek taraflı (sol taraf) sağırlığın bulunduğu tespit edilmiştir. Grupların karşılaştırılması sonucunda ise hiçbir grupta ve hiçbir dalga boyutunda istatistiksel olarak önemlilik tespit edilememiştir (P>0.05). Bu çalışmada farklı olarak yaş gruplarında yaş ilerledikçe duyma duyusunda azalma olmadığı, cinsiyetler arasında da farklılık olmadığı tespit edilmiştir. Bu çalışma Aksaray Malaklısı çoban köpeklerinde sağırlık taramasının yapıldığı ilk çalışma olma özelliğine sahiptir. Çalışma başta Aksaray Malaklısının yetiştirildiği Aksaray ilindeki yetiştirici elindeki hayvanları da içerecek şekilde genişletilmesi gerekmektedir.Öğe Sivas İlinde Yetiştirilen Aksaray Malaklısı Çoban Köpeklerinde İşitme Duyusuna Ait Normatif Datalar(2023) Özşensoy, Yusuf; Koçkaya, MustafaBaşta köpekler olmak üzere hayvanların görevlerini yerine getirmesi açısından işitme duyusu önemlidir. Çalışma- nın amacı Sivas'ta yetiştirilen Aksaray Malaklısı çoban köpeklerinde işitme duyusuna ilişkin normatif verilerin belirlen- mesidir (80 db HL’ de I., III. ve V. dalga latensleri). Çalışmada toplam 32 köpekte beyin sapı işitsel uyarılmış tepki (the brainstem auditory evoked response, BAER) testi uygulaması gerçekleştirildi. Ayrıca köpekler yaş, cinsiyet ve genel olacak şekilde gruplara ayrılmıştır. Gruplardaki hayvanların her iki kulağına ait her bir dalga için referans latens aralıkları için normatif datalar belirlenmiş, ayrıca dalga latens aralıkları arasında istatistiksel farklılıklar da araştırılmıştır. Genel olarak iki kulağın karşılaştırılmasında bağımsız gruplarda t testi kullanılmıştır. Cinsiyetlerin ve yaşların her iki kulak ortalamasına göre karşılaştırılmasında sırasıyla Mann-Whitney U ve Kruskall-Wallis testleri kullanılmıştır. Tüm istatistiksel analizler SPSS v.25 paket programında gerçekleştirilmiştir. Çalışma sonunda I., III. ve V. dalga latenslerinin genel, dişi, erkek, 9 ay dan küçük, 10-30 ay ve 31 ay ve üstü gruplar için ortalama değerleri sırasıyla 1.37-2.30-3.52; 1.36 -2.27-3.50; 1.45-2.40-3.58; 1.30-2.25-3.65; 1.30-2.25-3.55 ve 1.43-2.33-3.48 ms olarak bulundu. Grupların karşılaştırıl- masında dalga latenslerinde istatistiksel olarak önemlilik tespit edilememiştir (P>0.05). Bu çalışma ile Aksaray Malaklısı çoban köpeklerinde işitme duyusuna ait normatif veriler ilk kez belirlenmiştir. Bu normatif veriler, klinik muayenelerde ve Aksaray Malaklısı çoban köpeklerinin işitme duyusu üzerine gelecekteki çalışmalarda referans aralığı olarak kullanılabilecektir.Öğe Sokak Hayvanları Bakım ve Rehabilitasyon Merkezinde Bulunan Köpeklerde Elektrokardiyografi Verilerinin Araştırılması: Sivas İli Örneği(Sivas Cumhuriyet Üniversitesi, 2024) Koçkaya, Mustafa; Özşensoy, Yusuf; Alici, ŞahinKöpekler geniş çevre koşullarında gıda araştırarak zamanlarını geçiren sosyal hayvanlardır. Köpeklerin çevre koşullarından alınarak sınırlandırılmış barınak alanlarında bakılması fiziksel aktivitelerinde azalmaya yol açmaktadır. Köpeklerde fiziksel aktivitenin azalması mental parametrelerin olumsuz etkilenmesine hatta köpeklerde stres şekillenmesine neden olmaktadır. Uzun süreli stres durumlarında oluşan yanıtlar fizyolojik parametreleri etkilemektedir. Fiziksel aktivitenin azalması ve stres kalp fizyolojik parametreleri üzerinde de etkili olmaktadır. Çalışmanın amacı, barınak koşullarında tutulan köpeklerde elektrokardiyografi (EKG) parametrelerinin incelenmesidir. Çalışma kapsamında toplam 20 köpekte EKG verileri alınmış, cinsiyet (dişi ve erkek) ve yaş (3 yaş ve altı ile 3 yaş üstü) şeklinde gruplandırma yapılarak istatistiksel olarak karşılaştırılması Mann-Whitney U testi ile gerçekleştirilmiştir. Dişi ve erkek grupları arasında elektrokardiyografik parametrelerin tamamında istatistiksel olarak önemli bir fark bulunamamıştır (P>0.05). Yaş grupları arasında Q-T aralığı süresi açısından istatistiksel olarak farklılık bulunurken (PÖğe Sürü Koruyan ve Barınakta Tutulan Kangal Çoban Köpeklerinde Serum ve Tükürük CK, AST ve LDH Seviyelerinin Araştırılması(Sivas Cumhuriyet University, 2022) Koçkaya, Mustafa; Ekici, MehmetSürü koruma görevi yapan Kangal çoban köpeklerinin günlük fiziksel aktivitelerinin barınaklarda yaşayanlara göre daha fazla olduğu bilinen bir gerçektir. Fiziksel aktivite ve kas metabolizması arasındaki ilişki iyi bilinmektedir. Ancak literatürde sürüleri koruyan ve barınaklarda yaşayan Kangal çoban köpeklerinin kas metabolizmasındaki farklılıkları ortaya koyan bir çalışma bulunmamaktadır. Bu çalışmanın amacı, sürü koruma görevi yapan Kangal çoban köpekleri ile barınakta yaşayan Kangallar arasındaki kas metabolizması farklılıklarının araştırılmasıdır. Çalışmada sürü koruma görevi yapan ve barınakta tutulan genç Kangal köpekleri erkek ve dişi gruplarına ayrıldı toplam 32 adet köpek 4 gruba ayrıldı (n=8/grup). Serum ve tükürük örneklerinden kas metabolizması ile ilgili kreatin kinaz (CK), laktat dehidrojenaz (LDH) ve aspartat aminotransferaz (AST) parametreleri otoanalizör ile analiz edildi. Serum CK düzeyleri barınak köpeklerinde sürü koruma köpeklerine göre daha düşük bulunurken, en yüksek değer sürü koruyan dişilerde gözlendi. Tükürük CK seviyeleri barınak ve sürü koruyan erkek köpeklerde en yüksek, sürü koruyan dişi köpeklerde en düşüktü. Serum AST değeri en yüksek barınakta yaşayan dişilerde, en düşük serum AST değeri ise barınaktaki erkek köpeklerde tespit edildi. Ancak tükürük AST düzeyleri barınaktaki erkek ve dişi köpeklerde ve sürü koruyan erkeklerde yüksek olmasına rağmen sürü koruyan dişi köpeklerde ise düşüktü. Serum LDH düzeyleri barınaktaki dişilerde, sürüdeki erkek ve dişilerde yüksek, barınaktaki erkek köpeklerde ise düşüktü. Tükürük LDH düzeyleri barınak köpeklerinde en yüksek, sürü koruyan dişilerde en düşüktü. Bu çalışmada ilk kez Kangal çoban köpeklerinde serum ve tükürük örneklerinde kas metabolizması ile ilgili değişkenler (CK, AST ve LDH) araştırılmıştır.Öğe The effect of acute strenuous exercise on some physiological, blood and antioxidant system parameters in Kangal shepherd dogs with and without ankyloglossia(Burdur Mehmet Akif Ersoy University, 2020) Koçkaya, Mustafa; Ekici, MehmetThe aim of this study was to investigate the effect of acute strenuous exercise on some physiological, blood and antioxidant system parameters in Kangal shepherd dogs with ankyloglossia. In both groups, red blood cell, leukocyte, hemoglobin, mean corpuscular volume, hematocrit levels along with superoxide dismutase enzyme activity and malondialdehyde levels were increased after acute strenuous exercise compared to before exercise. In both groups, the biochemistry parameters of total protein, albumin, glucose levels were decreased after acute strenuous exercise compared to before exercise. In both groups, the heart rate, respiratory rate, body temperature physiological values were increased after acute strenuous exercise compared to before exercise. In comparison of the groups within themselves after acute strenuous exercise, the respiratory rate and body temperature values were increased more in the ankyloglossial group. When the data obtained were evaluated, it was found that acute strenuous exercise affected physiological data more in the dogs with ankyloglossia. This study is the first study on blood and antioxidant system parameters in Kangal shepherd dogs with ankyloglossia.
