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  • Küçük Resim Yok
    Öğe
    Antozolin HCL’in nazal mukosiliyer fonksiyon üzerine etkisi
    (Cumhuriyet Üniversitesi, 1988) Kunt, Tanfer; ,
    ÖZET Nazal patolojisi olmayan, sigara içmeyen 40 gönüllü üzerinde yapxlan bu çalışmada antihistaminik- lerin mukosiliyer aktivite üzerindeki etkileri araştı rıldı. Antihistaminik sonrası mukus transpor tunda Sakarin-Boya testi yardımıyla gecikme olduğu tesbit edildi. Testler arası farkın istatistiksel olarak anlamlı ve önemli olduğu görüldü (p<0.05). Sonuç olarak antihistaminiklerin mukus tabakası na etki ettiği ve mukosiliyer aktiviteyi azalttığı görülmüştür. Bu nedenle allerji dışındaki üst solunum yolu problemlerinde antihistaminiklerin daha dikkatli kullanılması gerekmektedir.
  • Küçük Resim Yok
    Öğe
    Clinical investigation of the transient evoked otoacoustic emission test in Crimean-Congo hemorrhagic fever
    (ELSEVIER SCI LTD, 2008) Engin, Aynur; Yildirim, Altan; Kunt, Tanfer; Bakir, Mehmet; Dokmetas, Ilyas; Ozdemir, Levent
    Objective: The aim of this study was to investigate cochlear damage in Crimean-Congo hemorrhagic fever (CCHF) infection. Methods: Thirty-two CCHF patients (study group) and 13 healthy people (controls) were included in the study. CCHF patients were also grouped for the presence of fever. CCHF was diagnosed with the presence of CCHF virus-specific IgM antibody or CCHF virus (CCHFV) antigen by ELISA. Cochlear damage was determined by a 'fail' in the transient evoked otoacoustic emission (TEOAE) test. Results: The proportion of TEOAE test 'fail' results in the CCHF patients was significantly higher than in the control group (p < 0.05). We found no increase in the proportion of TEOAE test 'fail' results related to fever in the study group. Conclusions: CCHF disease damages cochlear function regardless of fever. (c) 2007 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
  • Küçük Resim Yok
    Öğe
    Karyometric analysis of nasal polyps
    (İstanbul Üniversitesi, 2006) Yıldırım, Altan; Özdemir, Öztürk; Gül, Eylem; Yıldırım, Beyazıt; Elagöz, Şahende; Kunt, Tanfer
    Objectives: Nuclear characteristics of epithelial cells in nasal polyps were analyzed.Patients and Methods: The slides of 35 patients who undervvent surgery for nasal polyposis and 18 slides of normal mucosa were examined. The specimens were stained with hematoxylineosin. Tissue sections were analyzed by a CCD camera and the Karyotype Program of Human Cytogenetics Nomenclature System on a Macintosh Computer OS 9 . Fifty epithe­lial cells in each slide were randomly selected and transferred to the automated karyotyping system and photographed. The diameters of the nuclei were mea- sured and some peculiar nuclear features were exam- ined, including unsmooth appearance of the nuclear membrane, anaphase-bridge, and binucleation.Results: There were significant differences between nasal polyp and normal mucosa groups in terms of nuclear diameter, perimeter, and volüme, with ali variables being greater in the nasal polyp group p=0.001 . Unusual nuclear features differed significantly unsmooth nuclear membrane appearance, p