Yazar "Mahdavi, Mohammad" seçeneğine göre listele

Listeleniyor 1 - 5 / 5
  • Küçük Resim Yok
    Öğe
    A Simple and Efficient Procedure Toward 2-Thioxoquinazolin-4(1H)-One Derivatives
    (Jihad Daneshgahi, 2024) Shourkaei, Fateme Ahmadi; Ranjbar, Parviz Rashidi; Mahdavi, Mohammad; Tuzun, Burak; Taslimi, Parham
    A facile synthetic route for constructing 2-thioxoquinazolin-4(1H)-one derivative through cyclization reactions using readily available starting materials 2-aminobenzoic acids, alkyl/aryl amines, and carbon disulfide is described. These reactions occur under mild conditions, producing the desired products with good to high yields. Molecular docking was conducted to assess the activities of the 2-thioxoquinazolin-4(1H)-one derivative against breast cancer protein (PDB ID: 1JNX), liver cancer protein (PDB ID: 2H80), and colon cancer protein (PDB ID: 4UYA). Furthermore, an ADME/T analysis was performed to evaluate the impact of these compounds on human metabolism.
  • Küçük Resim Yok
    Öğe
    Carbon dots in antibiosis: Disinfection and sterilization
    (De Gruyter, 2023) Bayatani, Golnar; Matin, Mahdie; Alikhanian, Alireza; Mirhoseinian, Mahtab; Montazer, Mohammad Nazari; Tüzün, Burak; Mahdavi, Mohammad
    Antibiosis is the antagonism caused by the toxicity of secondary metabolites produced by the microorganisms. Our understanding of microbiology has improved as a result of research on antibiosis and its role in antibiotics. Nowadays Major bacterial diseases are becoming more resistant to standard antibiotic treatments, and multidrug-resistant bacteria are emerging at an alarming rate. High rates of morbidity and mortality are a challenge caused by antibiotic resistance in bacterial infections hence it is essential to synthesize and introduce new antimicrobial agents. Many studies have reported that Carbon Dots (CDs) show useful functions in antibiotic, antitumor, and antiviral activities. In this chapter several CD-based structures and their effects on antibacterial resistant bacteria's have been investigated. © 2023 Walter de Gruyter GmbH, Berlin/Boston.
  • Küçük Resim Yok
    Öğe
    Carbon dots in photodynamic therapy
    (De Gruyter, 2023) Matin, Mahdie; Mirhoseinian, Mahtab; Alikhanian, Alireza; Bayatani, Golnar; Montazer, Mohammad Nazari; Mahdavi, Mohammad; Tüzün, Burak
    Carbon dots (CDs) as a subclass of carbon-based nanoparticles were first discovered in 2004 and attracted the attention of scientists worldwide to their extinguish physiochemical properties; nowadays CDs have a broad range of applications including bioimaging, photocatalysis, fluorescent ink, sensors, lasers, and LED. In this chapter we will have a look into the synthesis, structure, and applications of CDs on biomedical science such as bioimaging, biosensors, drug and gene delivery, and photodynamic therapy. Photodynamic therapy is the method to transfer light energy to its surrounding using photosensitizer structure trials, which showed meaningful response to this approach in many types of malignancies, CDs could be a suitable option to use as photosensitizers. © 2023 Walter de Gruyter GmbH, Berlin/Boston.
  • Küçük Resim Yok
    Öğe
    MXenes in drug delivery
    (Elsevier, 2024) Alikhanian, Alireza; Montazer, Mohammad Nazari; Ahmadi, Baharan; Mahdavi, Mohammad; Sadeghian, Nastaran; Tüzün, Gamze; Tuzun, Burak
    before synthesizing MXenes a lot of two-dimensional (2D) structures were synthesized and various researches about these structures has done for years, but after 2011 that MXenes were discovered, and the number of 2D transition metal carbides and nitrides (MXenes) has progressively introduced. Those structures had applications in different fields. One field of interest is biology, and many biological applications have been suggested, such as drug delivery; in this chapter, we will explain important parameters and features in choosing components for drug delivery applications; for instance, cellular uptake, biocompatibility, and biodistribution. And focus on some MXene-based structures which are the best example of drug delivery application of MXenes introduced in different studies for instance MXene/cobalt, MXene/agarose hydrogel, and MXene/AuNRs. These structures not only have stable structures and well-synthesized methods but also have all of the crucial features (such as cellular uptake, biocompatibility, and biodistribution) for a good drug delivery component. © 2024 by Elsevier Inc. All rights reserved, including those for text and data mining, AI training, and similar technologies.
  • Küçük Resim Yok
    Öğe
    MXenes synthesis and characterization
    (Elsevier, 2024) Ahmadi, Baharan; Montazer, Mohammad Nazari; Bozorg, Ali; Mahdavi, Mohammad; Sadeghian, Nastaran; Tüzün, Gamze; Tuzun, Burak
    Because of their adaptive nature and great surface chemistry, two-dimensional (2D) transition metal carbides, nitrides, and carbonitrides, often called MXene, are versatile materials. Physical and chemical diversity has defined MXenes as a promising 2D material with many applications. MXenes are prepared by selectively etching particular atomic layers from their layered precursors, known as the MAX phase. Synthesized MXenes prepared by hydrofluoric acid etching have an accordion-like morphology, referred to as multilayer MXene or, when less than five layers, several layers MXene. In light of the remarkable advances in the MXene field, it is appropriate to examine the most relevant properties of these MXenes and highlight their potential applications. The purpose of this section is to review the most important fundamental and technological aspects, and synthesis aspects of MXenes, ranging from the structural and physicochemical properties of these compounds to their potential applications and devices, with a focus on medical applications and drug delivery. © 2024 by Elsevier Inc. All rights reserved, including those for text and data mining, AI training, and similar technologies.