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Öğe Gebe rat uterin horn modelinde, ratın kendi amniyotik membranın, adezyonlar üzerine etkisi(Cumhuriyet Üniversitesi, 2011) Mutlu, Ahmet Emin; Boztosun, AbdullahPostoperatif adezyon oluşmasını azaltmak için çok çeşitli ajanlar denenmiş, ancak henüz yeterli etkinlikte bir ajan bulunamamıştır. Bu çalışmada amniotik membranın adezyon oluşmasındaki etkisi rat uterin horn modelinde araştırılacaktır. 40 gebe ratın 8'ine sadece sezaryen yapılacak. 8 rata sezaryen yapılacak ve insizyon hattı üzerine kendi amniyotik membranı örtülecek. 8 rata sezaryen yapılacak ve insizyon hattı üzerine Düşük Molekül Ağırlıklı Heparin (DMAH) damlatılacak. 8 rata sezaryen yapılacak ve insizyon hattı üzerine metilen mavisi püskürtülecek. 8 rata sezaryen yapılacak ve insizyon hattı üzerine Seprafilm© kapatılacak. Dört hafta sonra ratlar sakrifiye edilerek uterin horn üzerindeki adezyonlar yaygınlık ve şiddet yönünden derecelendirilecek.Öğe Gebe ratlarda sezaryen operasyonu sonrası, adezyonların önlenmesinde clexane® enoksaparin sodyum ve metilen mavisi'nin etkinliklerinin karfiılafitırılması(2012) Mutlu, Ahmet Emin; Boztosun, Abdullah; Sümer, Dinçer; Yanık, Ali[Abstract Not Available]Öğe Prevalence of cervical cytological abnormalities in Turkey(WILEY, 2009) Kara, Fadil; Kiran, Guerkan; Metindir, Jale; Ozan, Hakan; Ozalp, Sinan; Vardar, M. Ali; Zeren, Handan; Dilek, Saffet; Bozkaya, Hasan; Guven, Sueleyman; Ersoz, Safak; Acikalm, Arbil; Meydanli, Mutlu; Cetinarslan, Ilknur; Gokaslan, Huesnu; Eren, Funda; Celik, Cetin; Yilmaz, Osman; Celik, Huesnue; Aksaz, Zeliha; Kocak, Cengiz; Bagci, Hafize; Davutoglu, Bilge Sel; Hakverdi, Ali Ulvi; Soysal, Mehmet Emin; Kaya, Guelcan; Yanik, Ali; Arici, Sema; Cetin, Halit; Mutlu, Ahmet Emin; Kolusari, Ali; Kosem, Mustafa; Sahin, Guler; Demirturk, Fazli; Gultekin, Murat; Karaca, Mehmet; Harma, Mehmet; Harma, Muege; Batur, Sebnem; Demirbag, Nilgun; Baykal, Cem; Dogan, Isin; Sam, Asli DemirObjective: To evaluate retrospectively the prevalence of cervical cytological abnormalities in patient records obtained from healthcare centers in Turkey. Method: Demographic characteristics and data on cervical cytological abnormalities were evaluated from patients who underwent flap tests in healthcare centers in 2007. Results: Data were collected from 33 healthcare centers totaling 140 334 patients. Overall, the prevalence of cervical cytological abnormalities was 1.8%; the prevalence of ASCUS, ASC-H, LSIL, HSIL, and AGC was 1.07%, 0.07%, 0.3%, 0.17%, and 0.08%, respectively. The prevalence of preinvasive cervical neoplasia was 1.7% and the prevalence of cytologically diagnosed invasive neoplasia was 0.06%. Conclusion: The abnormal cervical cytological prevalence rate in Turkey is lower than in Europe and North America. This might be due to sociocultural differences, lack of population-based screening programs, or a lower HPV prevalence rate in Turkey. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.Öğe Servi?kovaji?nal smearde epi?telyal hücre anomali?si? saptanan hastalarin, kolposkopi?k bi?yopsi? sonuçlarinin de?erlendi?ri?lmesi?(2012) Boztosun, Abdullah; Mutlu, Ahmet Emin; Özer, Hatice; Aker, Handan; Yanik, AliObjective: The aim of this study was evaluate a colposcopy and cervical biopsy results of patients who had diagnosed epithelial cell abnormalities. Material and Method: Between January 2007 - May 2011, outpatient clinic records of 303 patients that obtained from Department of Gynecology and Pathology of Cumhuriyet University School of Medicine were evaluated. Results: Total examined in 11,681 cervicovaginal smear of 303 (%2,6) is "epithelial cell abnormalities" were found. Epithelial cell abnormalities cases with in 194 (%64) patient is Atypical Squamous Cells of Undetermined Significance (ASC-US); 35 (%11,5) patient is Atypical Squamous Cells, Suggestive of High Grade (ASC-H); 36 (%11,9) patient is Low Grade Squamous Intraepithelial Lesion (LSIL); 9 (%3) patient is High Grade Squamous Intraepithelial Lesion (HSIL); 9 (%3) patient is Squamous Cell Carcinoma (SCC); 2 (%0,6) patient is Adenocarcinoma as defined. İn 18 patient (%6) had Atypical Glandular Cells (AGC). In premalignant lesions, cervical intraepithelial neoplasia (CIN), carcinoma in situ and invasive carcinoma that were diagnosed by cervical biopsy were considered positive results. Patients in 10 cases ASC-US (%3,3), 6 cases ASC-H (%2), 6 cases LSIL (%2), 6 cases HSIL (%2), 1 case AGC (%0,3), 6 cases SCC (%2) and 2 cases Adenocarcinoma (%0,6) were detected positive results. In total, 81 (26.7%) patients of cervical biopsy taken and 37 (12.2%) patients, positive results were obtained. Conclusion: Follow-up of patients with glandular or epithelial cell abnormalities in smear is important to both early detection and reduction of incidance of invasive cervical cancer in smear is important to both early detection and reduction of incidance of invasive cervical cancer.
