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Mortality in patients with hypoxic ischemic encephalopathy treated with therapeutic hypothermia
(Cukurova Univ, Fac Medicine, 2025) Tunc, Gaffari; Korgali, Elif Unver; Mutlu, Muhammet Ali; Unsal, Gulsah; Gulturk, Esra Akaydin
Purpose: Hypoxic-ischemic encephalopathy is a heterogeneous clinical syndrome that occurs in the perinatal period and is characterized by altered consciousness or seizures, respiratory depression, and hypotension. The aim of this study was to evaluate mortality in hypoxic-ischemic encephalopathy patients receiving therapeutic hypothermia. Materials and Methods: The study included 97 hypoxicUnit. The cases were evaluated for mortality and were divided into two groups: group 1 (n: 9, non-survivors) and complications of hypoxic-ischemic encephalopathy, APGAR scores, blood support, and laboratory parameters were evaluated for mortality. the risk of death. Conclusion: Mortality rates were significantly higher cases that developed Meconium aspiration syndrome associated hypoxic-ischemic encephalopathy than hypoxic-ischemic encephalopathy cases without meconium aspiration syndrome. A low APGAR score, increased number of intubation days, acute kidney injury, thrombocytopenia, and need for fresh frozen plasma were associated with a high risk of mortality in infants receiving therapeutic hypothermia for hypoxic-ischemic encephalopathy, and the presence of meconium aspiration syndrome significantly increased this risk.