Yazar "Ozenoglu, Aliye" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    Differences in the body composition and biochemistry in women grouped as normal-weight, overweight and obese according to body mass index and their relation with cardiometabolic risk
    (VERSITA, 2010) Ozenoglu, Aliye; Ugurlu, Serdal; Can, Gunay; Sarkis, Cihat; Demirel, Yeltekin
    Morbidity of obesity-related diseases tends to increase due to a rise in the body mass index (BMI). We aimed to investigate how the body composition and biochemical parameters change while BMI increases in adult women were categorized as so: as normal weight, overweight and obese. Our objectives are to study the effects of those changes in the development of metabolic disturbances and to find out which parameters are the most sensitive to predict cardiometabolic risks. Three hundred and twenty two records of adult women (mean age: 38.62 +/- 12.71 year) who admitted to our unit concerning about losing or preserving their weights, were analyzed in the study. All patients had undergone anthropometric measurements and body composition analyses as well as some biochemical tests. Body composition analyses were performed by means of the Bioelectrical Impedance Analyzer (BIA). Increase in BMI significantly increased the body fat, blood sugar, insulin, triglyceride and uric acid levels. BMI and circumference of the waist were significantly and negatively correlated with the ratio of body water and lean mass/fat mass. However they were positively correlated with the ratio of fat mass and basal metabolism. Furthermore, it was also found that BMI and circumference of the waist were significantly and positively correlated with level of fasting blood sugar, insulin, triglyceride, homeostasis model assessment insulin resistance (HOMA-IR), uric acid and fibrinogen levels, and negatively correlated with high density lipoprotein (HDL) cholesterol level. In multiple regression analyses, circumference of waist measurements was significantly correlated with insulin, triglyseride and HDL, whereas the correlation between BMI and these parameters was not found significant. Total body fat mass (as %) showed significant correlation only with HDL-C level. It could be said that obesity which is a disorder that causes many health complications and affects the quality of life in the short and long term could be prevented or cured by keeping negative environmental conditions under control. According to our results, visceral adipose tissue (VAT) measurement was thought to be more related for metabolic and cardiovascular disorders rather than BMI. We also propose to test fasting blood glucose, insulin, triglyceride, HDL, fibrinogen, homocystein (HOM) levels along with VAT measurements to predict more truly about not only global cardiometabolic risk but also dementia in later life.
  • Küçük Resim Yok
    Öğe
    METABOLIC DISTURBANCES ARISING OUT OF PSYCHIATRIC PHARMACOTHERAPIES AND THE IMPORTANCE OF DIETETIC INTERVENTION IN ITS TREATMENT
    (NOBEL ILAC, 2009) Ozenoglu, Aliye; Ugurlu, Serdal; Can, Guenay; Eker, Engin; Elmacioglu, Funda
    Objective: The aim of this study was to compare alterations at body weight, composition and blood biochemistry in adult patients (age: 40.54+/-12.82 years) taking pharmacotherapy for their psychiatric disorders and adults (age: 38.61+/-12.70 years) who were not taking psychiatric treatments. Material and Method: A total of 128 (111 female, 17 male) patients in study group, and 347 (312 female, 35 male) who didn't have any endocrinologic-metabolic or psychiatric disorders and were not on any drug treatment in control group were evaluated. At the beginning, antropometric measuremnts, body composition analysis with a bioelectrical impedance analyzer and blood samples for some biochemical tests (Fasting blood glucose, insulin, HbA1C, triglyceride, total cholesterol, HDL, LDL blood counting, vitamin B12, folate, zinc, CRP, homocystein, cortisol,fibrinogen, TSH, uric acid levels) were taken for all patients. Results were analyzed statistically by using a computer program SPSS for Windows 10.0 with Mann Whitney U, pearson corelation, multipl regression analysis and Student t tests. Results: Mean treatment length with psychiatric drugs of the patients was 5.29+/-5.99 year, and mean weight gain at this period was 12.05+/-6.80 kg. Most of the patients have been taking more than one type of psychiatric drugs and their distrubition were 71.9% antidepressants, 31.3% anti-psychotics, 25.0% mood stabilyzers and 10.9% anxyolitics. Mean weight gain, body mass index (BMI), waist and hip circumferences, and body,fat percent of patients in study group were higher than in control group. Also while blood glucose, insulin, triglyceride, TSH,fibrinogen levels were statistically higher; total protein, albumin, zinc and folat levels were find statistically lower in study group. When all participants in both of the groups were divided as normal weight, owerweight and obese according to BA,11, it was found that while BMI increasing waist and hip circum-ferences, body fat percent, blood insulin, HbA1C levels increased but HDL levels decreased significantly. In study group, treatment period corelated positifly with body fat percent, blood insulin, TSH and homocystein levels; but corelated negatively with albumin level. Weight gain corelated positively with waist and hip circumfernces, body fat percent, blood insulin, trigliseride and TSH levels; but corelated negatively with folat level in patients taking psychiatric drugs. Conclusion: According to results of this study, it was shown that patients treated with psychiatric drugs are sensitive to metabolic and cardiovascular diseases along with obesity. So, it was though that patients who need psychiatric pharmacotherapies may have benefit if evaluated and treated by a team consisting endocrinologic, metabolic and nutritional specialists. A dietician knowledgeable and experienced in medical nutrition therapies on endocrine-metabolism and psychiatric disorders areas has an importantrole for collaborating with other related units.
  • Küçük Resim Yok
    Öğe
    The Reference Values of Body Composition for Adult Females Who are Classified as Normal Weight, Overweight or Obese Accoding to Body Mass Index
    (Medi+World Int, 2008) Ozenoglu, Aliye; Ugurlu, Serdal; Can, Gunay; Hatemi, Husrev
    Objective: The aim of this study was to conduct the reference values for body composition measured with Bioelectrical Impedance Analyser (BIA) of adult females without any endocrinologic and/or metabolic disturbances, according to their body mass index (BMI) and grouped as normal, overweight, obese and morbidly obese. Patients and Methods: A total of 327 female subjects were taken into the study. Their body compositions were measured with BIA, in addition to measurement of their weight, height, and waist and hip circumferences. Results were statistically analysed with ANOVA test. Results: As BMI got higher, percentages of body fat and basal metabolism (BM) increased significantly; but percentages of body water and fat free mass, and lean/fat ratio showed a significant decrease. In addition, waist and hip ratios, percentage of body fat and BM showed a significant positive corelation with BMI. Conclusion: We concluded that our results could be used as reference values for studies on body composition, especially to predict the degree of body fatness of obese patients and also nutritional status of patients who need nutritional supports.