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Öğe A current view on the neglected topic of male child sexual abuse in the context of literature(Wiley, 2024) Sari, Seda Aybuke; Bilac, Oznur; Erten Almak, Tilbe; Butun, CelalDespite the growing numbers, awareness and reporting rates of male child sexual abuse (MCSA) are still well below the real values, especially in developing countries like Turkey. We examined MCSA to determine the predisposing factors, the characteristics of perpetrators and victims, and the consequences of sexual abuse in a Turkish sample. We retrospectively analysed the files and forensic reports of 51 MCSA victims aged between 6 and 18. The mean age of children was 13.6 & PLUSMN; 3.8 years, and the mean age at the time of abuse was 11.1 & PLUSMN; 3.52. The average exposure time for sexual abuse was 91 & PLUSMN; 226.8 days, and the frequency was 2.4 & PLUSMN; 2.47 times. 17.6 per cent of them had previously been sexually abused. Disclosure times until legal notification was 240.1 & PLUSMN; 552.25 days. Most (56.9 per cent) had suffered anal penetration, developed post traumatic stress disorder, and needed medical treatment. Most perpetrators (58.8 per cent) were strangers outside the family, reaching the children from the neighbourhood. In conclusion, although the number of our sample is limited, the results of our study will contribute valuably to the literature, given that there are few studies on MCSA. Further studies with large samples evaluating MCSA in multidimensional ways are needed to raise awareness and protect vulnerable children.Öğe Adaptation of the Problem Areas in Diabetes-Teen Scale into Turkish and examination of its psychometric properties: a validity and reliability study(Turkish J Pediatrics, 2024) Sari, Seda Aybuke; Agadayi, Ezgi; Celik, Nurullah; Karahan, Seher; Komurluoglu, Ayca; Doger, EsraObjective. Management of type 1 diabetes (T1DM) is quite challenging for both adolescents and their families. In this study, we aimed to translate the 14-item Problem Areas in Diabetes-Teen (PAID-T) scale, which measures variables that influence diabetes distress, to Turkish and investigate the Turkish version's reliability and validity. Methods. One hundred and ninety-four adolescents with T1DM participated in the study. PAID-T and forms for sociodemographic and diabetes characteristics were used for data collection. The scale's content validity was checked using the Davis technique. Cronbach's alpha was used to analyze the scale's internal reliability and the testretest for the scale's reliability. Exploratory factor analysis (EFA) was utilized to examine the factor structure. The fit of the scale was assessed using confirmatory factor analysis (CFA). Results. Of the participants, 54.6% (n=106) were girls. The content validity index values of the scale items ranged between 0.86 and 1.0. The PAID-T scores of girls and boys were similar. No significant difference was found between PAID-T scores with sociodemographic data and diabetes characteristics (p>0.05). The test-retest correlation coefficient of the scale was found to be 0.952. The three-factor (emotional burden, family and friend distress, and regimen-specific distress) model identified in EFA explained 61.8% of the common variance. Fit analysis was performed using CFA for the three-factor model, which did not show adequate fit (x2/df = 2.402, GFI = 0.822, CFI = 0.815, NFI = 0.727, NNFI = 0.772, RMSEA = 0.118). The Cronbach alpha value of the scale was 0.864. Conclusion. The Turkish version of the 14-item PAID-T showed moderate validity and strong reliability. Accordingly, it can be used as a reliable measurement tool to assess diabetes stress in adolescents with T1DM.Öğe Association of Suicide Attempt With Seroprevalence of Toxoplasma gondii in Adolescents(Lippincott Williams & Wilkins, 2019) Sari, Seda Aybuke; Kara, AhuIn this study, we aimed to explore the potential pathophysiological relationship between suicide attempts and Toxoplasma gondii infection. Fifty patients aged between 12 and 18 years who attempted suicide and 50 healthy adolescents were included in this study. All adolescents were evaluated by a child psychiatrist using a semistructured interview and Rosenberg Self-Esteem Scale (RSES), Children's Depression Inventory (CDI), and Inventory of Parent and Peer Attachment. T. gondii IgM and IgG antibodies of patients and control subjects were analyzed from blood samples by enzyme-linked immunosorbent assay. Psychiatric disorders particularly mood disorders were more common in adolescents in the patient group. Adolescents attempting suicide were found to have worse relationships with their parents; their CDI scores were higher, and their RSES scores were lower than their healthy peers. There were no significant differences between the patient and the control groups in terms of Toxoplasma IgG antibody positivity. Although the seropositivity of Toxoplasma IgG antibody was higher in the patient group than that in the control group, the difference between the two groups was not statistically significant.Öğe Body Perception, Self-Esteem, and Comorbid Psychiatric Disorders in Adolescents Diagnosed with Polycystic Ovary Syndrome(Elsevier Science Inc, 2020) Sari, Seda Aybuke; Celik, Nurullah; Cicek, Ayla UzunStudy Objective: To investigate adolescents with polycystic ovary syndrome (PCOS) in terms of body perception, self-esteem, and comorbid psychiatric diseases by comparing them with their healthy peers. Design: Cross-sectional design. Setting: The Department of Child and Adolescent Psychiatry and the Department of Pediatric Endocrinology outpatient clinic of Cumhuriyet University in Sivas, Turkey. Participants: Fifty female adolescents aged 12-18 years who were diagnosed as having PCOS and 37 healthy adolescents aged 12-18 years. Interventions and Main Outcome Measures: All adolescents were evaluated by a child and adolescent psychiatrist using a semistructured interview (Schedule for Affective Disorders and Schizophrenia for School-Age Children) and asked to complete the Rosenberg Self-Esteem Scale, Children's Depression Inventory, and Body Image Scale. Results: The rate of psychiatric disorders in the PCOS group was significantly higher than in the control participants (16/50 (32%) vs 5/37 (13.5%), respectively; P = .046). The most common disorder was major depressive disorder. The Rosenberg Self-Esteem Scale and Body Image Scale scores of the PCOS group were lower (P = .03; P ! .001, respectively), and Children's Depression Inventory scores were higher (P = .03) than in the control group. There was no significant relationship between obesity, hirsutism, and insulin resistance with any psychiatric disorders in the PCOS group. Conclusion: Adolescents with PCOS had more psychopathology than their peers. Moreover, their self-esteem was lower and their body perceptions were more dissatisfied compared with their peers.Öğe CHIARI MALFORMATION TYPE 1 IN AN ADOLESCENT WITH CONVERSION DISORDER(Medicinska Naklada, 2022) Sari, Seda Aybuke; Ozdemir, Oyku; Ozum, Unal[Abstract Not Available]Öğe Coexistence of Autism and Eating Disorder: a Case Report(YERKURE TANITIM & YAYINCILIK HIZMETLERI A S, 2018) Sari, Seda AybukeA case of autism who lost 18kg within one and a half months with vomiting episodes following binge eating attacks and refused to eat solid foods within the last ten days is presented in this study. As solid food intake was completely stopped and fluids were vomited out, it was decided to hospitalize the patient who was admitted to the psychiatry clinic with a diagnosis of feeding or eating disorders not elsewhere classified (FED-NEC). Intravenous hydration and 15mg/day olanzapine were initiated. Studies on children with autism spectrum disorders (ASD) showed that these children had atypical eating patterns and rituals compared to a healthy control group.Öğe Determining the probability of juvenile delinquency by using support vector machines and designing a clinical decision support system(Churchill Livingstone, 2020) Ucuz, Ilknur; Cicek, Ayla Uzun; Ari, Ali; Ozcan, Ozlem Ozel; Sari, Seda AybukeIt is a known fact that individuals who engaged in delinquent behavior in childhood are more probable to carry on similar behavior in adulthood. If the factors that lead children to involve in delinquency are defined, the risk of dragging children into crime can be detected before they are involved in crime and delinquency can be prevented with appropriate preventive rehabilitation programs, in the early period. However, given that delinquent behavior occurs under the influence of multiple conditions and factors rather than a single risk factor; the need for diagnostic tools to evaluate multiple factors together is obvious. Artificial intelligence-based clinical decision support systems have already been used in the field of psychiatry as well as many other fields of medicine. In this study, we assume that thanks to artificial intelligence-based clinical decision support systems, children and adolescents at risk can be detected before the criminal behavior occurs by addressing certain factors. In this way, we anticipate that it can provide psychiatrists and other experts in the field.Öğe Effects of agmatine, glutamate, arginine, and nitric oxide on executive functions in children with attention deficit hyperactivity disorder(Springer Wien, 2020) Sari, Seda Aybuke; Ulger, Dilara; Ersan, Serpil; Bakir, Deniz; Uzun Cicek, Ayla; Ismailoglu, FiratIn this study, we aimed to investigate the effects of agmatine, nitric oxide (NO), arginine, and glutamate, which are the metabolites in the polyamine pathway, on the performance of executive functions (EF) in attention deficit hyperactivity disorder (ADHD). The ADHD group included 35 treatment-naive children (6-14 years old) who were ewly diagnosed with ADHD. The control group consisted of 35 healthy children with the same age and sex, having no previous psychiatric disorders. In the study groups, Stroop test (ST) and trail making test (TMT) were used to monitor EF, and blood samples were collected to measure agmatine with ultra-high-performance liquid chromatography and NO, glutamate, and arginine with enzyme-linked immunosorbent assay (ELISA). The EFs were significantly impaired in the ADHD group. The agmatine and arginine levels of the ADHD group were significantly higher than their peers. The NO and glutamate levels were also higher in the ADHD group compared to the control group, but these differences did not reach statistical significance. Children with ADHD had more difficulties during EF tasks compared to healthy children. The elevated NO and glutamate levels may be related with the impairment during EF tasks. Therefore, agmatine and arginine may increase to improve EF tasks through its inhibitory effect on the synthesis of NO and glutamate. Further studies are needed about polyamine pathway molecules to shed light on the pathophysiology of ADHD.Öğe Evaluation of incest cases in Sivas: Ten-year retrospective study(Wiley, 2024) Butun, Celal; Beyaztas, Fatma Yucel; Sari, Seda Aybuke; cicek, Ayla Uzun; Kaya, Asiye BurcuAlthough incest is generally perceived as all kinds of verbal, non-verbal, physical and visual sexual behaviour of family members and close relatives toward children, it is also a special type of sexual abuse defined as consensual sexual intercourse between close relatives or between minors who are legally prohibited from marrying. This study aimed to analyse the sociodemographic data, physical-mental examination and laboratory findings of the incest cases. Incest cases among sexual abuse and sexual assault cases sent to Sivas Cumhuriyet University Hospital Forensic Medicine outpatient clinic for examination between 2012 and 2021 were evaluated. Statistical analysis of the data was performed using the SPSS 23.0 program. P-values below 0.05 were considered significant. The records of 61 incest victims were retrospectively analysed. The cases were examined in terms of age, gender, incident, perpetrator, type of abuse, examination findings and mental status. Fifty-four (88.5%) of the incest victims were female, and the highest rate (n = 9, 14.8%) was 16 years old. Most of the victims were high school graduates (29%), 56% were in a nuclear family 57.4% of the assailants were family members, most of the case reports (73.8%) were made by the victim herself/himself, and the most common place of incident (70.3%) was the victim's home. In this study, the clinical, social and forensic outcomes of incest cases, which have many causes and tragic consequences, were investigated, and it was aimed to contribute to the solution of the problem by discussing the literature. Child abuse causes actual or potential harm to the child's health, development or dignity. Incest is a situation that is difficult to detect and legal process and is a rather ignored public health problem in developing countries such as Turkey. Sexual assault may be an ongoing condition in those who were abused during childhood.Öğe Evaluation of sexually abused adolescents cases by the repertory grid technique: a cross-sectional study(Cukurova Univ, Fac Medicine, 2019) Cicek, Ayla Uzun; Fettahoglu, Emine Cigil; Ozatalay, Esin; Sari, Seda AybukePurpose: In this study, we aim to explore how the adolescent girls who have experienced sexual abuse (SA) perceives themselves, their families and their surroundings, using repertory grid technique (RGT) within the scope of personal construct theory (PCT). Materials and Methods: 30 adolescent girls with SA and 25 adolescent girls with no SA were included in the study. RGT was used to assess how the adolescents perceive themselves, their families and their surroundings and the Rosenberg Self-Esteem Scale (RSES) was used to measure self-esteem. Individual and familial characteristics of the participants were evaluated with a sociodemographic data form developed by the researchers. Results: Based on RGT, it was found that adolescents who had experienced SA perceived themselves as more different and distant from their mothers, their siblings and their close female friends compared with those with no SA. However, they perceived themselves as more similar to their friends that they think who have negative properties. In addition, it was determined that the sexually abused girls had excessive cognitive complexity and higher self-ideal self' discrepancy than those of nonabused controls. Sexually abused adolescents had lower self-esteem on the RSES scores. Conclusion: SA negatively affects self-perception and perception of the surrounding and it damages self-confidence and the confidence towards the world, thus sexually abused adolescents should be followed up for these problems.Öğe Evidence supporting the role of telomerase, MMP-9, and SIRT1 in attention-deficit/hyperactivity disorder (ADHD)(Springer Wien, 2020) Uzun Cicek, Ayla; Mercan Isik, Cansu; Bakir, Sevtap; Ulger, Dilara; Sari, Seda Aybuke; Bakir, Deniz; Cam, SelimGrowing evidence suggests that telomeres, telomerase, matrix metalloproteinase-9 (MMP-9), andSIRT1(sirtuin1) are involved in the pathophysiology of neuropsychiatric and neurodevelopmental disorders. However, whether these molecules are contributors to attention-deficit/hyperactivity disorder (ADHD) has been little explored and poorly understood. This study aimed to determine the potential role of telomerase, MMP-9, andSIRT1in children with ADHD. The study was performed on 46 children with ADHD aged between 8 and 14 and 43 healthy children matching in age and gender. Children were evaluated by Kiddie-Sads-Present and Lifetime Version, Conners' Parent Rating Scale-Revised Short Form (CPRS-RS) and Stroop test. Serum telomerase, MMP-9, andSIRT1levels were measured by a quantitative sandwich enzyme-linked immunosorbent assay. MMP-9 and telomerase levels were significantly higher andSIRT1levels were significantly lower in patients with ADHD than those of controls. All three molecules were significantly associated with both the severity of ADHD symptoms and cognitive functions. This is the first attempt to indicate that the important role of telomerase, MMP-9, andSIRT1in ADHD, and the association of all these molecules with the severity of ADHD and cognitive functions, but future studies are required to verify these results.Öğe Examining the Relationship Between Preventable Psychiatric Problems and Child Extremity Fractures(Pera Yayincilik Hizmetleri, 2022) Sari, Seda Aybuke; Pazarci, Ozhan; Kilinc, Seyran; Cicek, Ayla UzunObjective: Extremity fractures (EF) are among the most common causes of admission to hospitals in children. We aimed to evaluate children treated for EFs by comparing them with the control group from a psychiatric perspective. Method: Thirty-six children aged between 3 and 17 years who administered to the Orthopedics and Traumatology clinic due to EF were included in the study. 36 children of similar age and gender with the study group were included as the control group. A child psychiatrist evaluated all children included in the study. A psychiatric diagnosis interview was conducted. The parents filled out the Conner's Parent Rating Scale-Revised Short Form (CPRS-R:S). Results: Of the cases in the patient group, 66.7% were male. The ratio of rural residents in the patient group was higher compared to the control group. The most common fracture location was lower extremity (55.6%). The most common cause of the fracture was falling (52.8%). In the patient group, the ratio of the children who had previously experienced fracture was 36.1%. Psychopathology was detected to be at a higher level in the patient group. The most common was Attention Deficiency and Hyperactivity Disorder (ADHD). Children in the patient group scored higher on the CPRS-R:S than the control group. Conclusion: Children with EF exhibited more impulsive and hyperactive behaviours than controls and had more psychopathology. For this reason, it is essential to evaluate children who apply due to fracture in terms of psychopathology.Öğe A Nonrandom Sample of 55 Sexual Abuse Cases in Sivas(INT SCIENTIFIC INFORMATION, INC, 2017) Butun, Celal; Yildirim, Ali; Ozer, Erdal; Yilmaz, Eda; Sari, Seda AybukeBackground: Sexual abuse in childhood is a significant public health problem because of the destructive results both to the individual and to the community. The aim of this study was to examine the sociodemographic characteristics of children who were victims of sexual abuse, the relationship of the victim and abuser, and the findings of sexual abuse. Material/Methods: An examination was made of the results of forensic medicine and psychiatric evaluations of child victims of sexual abuse. The sociodemographic characteristics of the cases and the characteristics of the incidents of sexual abuse were evaluated at the Forensic Medicine Department of Cumhuriyet University between 2013 and 2016. Results: A total of 55 cases were included in the study, comprising eight males (14.5%) and 47 females (85.5%) in the age range of 5-17 years. The vast majority of the cases were high school students. The place of the abuse incident was the home of the victim or the perpetrator in 29 cases (52.7%). The sexual abuse was determined to be bodily penetration in 32 cases (58.1%). In 32 cases (58.1%), the perpetrator was known to the victim. Conclusions: The study findings that the perpetrator of the sexual abuse was known to the child, that predominantly female children were attacked, and the low sociocultural level of the cases were consistent with other studies reported in the literature. To prevent sexual abuse of children, to make an early diagnosis, and to provide rehabilitation for the abused children, it is essential that the evaluations of these cases are made using a professional multidisciplinary approach.Öğe Olfactory Function in Depressed Adolescents(Lippincott Williams & Wilkins, 2020) Cicek, Ayla Uzun; Altuntas, Emine Elif; Bora, Adem; Sari, Seda AybukeSome researchers have suggested that olfactory deficits might be a sensitive marker for depression in adults. However, olfactory function has not been well studied in relation to depression among children and adolescents. The aim of this study was to evaluate the effect of depression on olfactory function of adolescents. The olfactory threshold, odor identification, and discrimination abilities of adolescents aged 12 to 17 (43 adolescents with major depressive disorder and 43 healthy controls) alongside their sum were evaluated using the Sniffin' Sticks extended test. Olfactory scores were similar between the groups. However, depressed adolescents perceived their own olfactory function scores significantly lower than the measured values. No correlation was found between olfactory scores and age, sex, severity of depression, and duration of depression. This study conducted with a small sample size revealed that olfactory function of the adolescents with depression was similar to olfactory function of the healthy adolescents. It is required to conduct further adequately powered, longitudinal studies in order to verify these results.Öğe Prevalence of autism spectrum disorder (ASD) in Sivas City Center and ASD awareness of healthcare professionals in family health centers(Cukurova Univ, Fac Medicine, 2021) Golbasi, Hatice; Demirel, Yeltekin; Karaca, Sanem Nemmezi; Cicek, Ayla Uzun; Sari, Seda AybukePurpose: The aim of this study was to determine the prevalence of autism spectrum disorder (ASD) in Sivas City Center and to investigate the ASD awareness of healthcare professionals working in Family Health Centers (FHC). Materials and Methods: The sample of the study consisted of 752 children aged between 18-72 months, 90 family physicians and 78 family health personnel (FHPs). The ASD Knowledge-Attitudes Scale and the ASD Awareness Questionnaire were administered to healthcare professionals. The Modified Checklist for Autism in Toddlers (M-CHAT) was applied to all of the children. Results: The mean scores of the ASD Knowledge-Attitude Scale and ASD Awareness Questionnaire of the family physicians were significantly higher than FHPs. The risk rate for ASD in screening was 6.25% (n=47), and the prevalence rate was 0.53%. Twenty of these children who were found to be at risk were evaluated by a child and adolescent psychiatrist. Of the 20 evaluated children, 7 were found to be normal, while 4 had a diagnosis of ASD, and 9 had other psychiatric diagnoses. Conclusion: This study showed that the prevalence rate of ASD in Sivas City Center is 0.53% and that the ASD awareness of family physicians is higher than that of FHPs. We believe that training programs to increase the awareness of healthcare professionals about ASD can contribute to the early detection of children with ASD.Öğe Psychometric Properties of the Turkish Validity and Reliability of the Parent Diabetes Distress Scale(Galenos Publ House, 2023) Karahan, Seher; Agadayi, Ezgi; Sari, Seda Aybuke; Celik, Nurullah; Tan, Ayca Komurluoglu; Doger, EsraObjective: The aim of this study was to evaluate the validity and reliability of the Turkish translation of the Parent Diabetes Distress Scale (PDDS). Methods: The PDDS is a 5-point Likert-type scale with 20 items. After obtaining permission from the scale developers, the study commenced. First, a systematic adaptation of the scale into the Turkish language was performed including translation, expert panel review, back translation, and pilot study. Test-retest was applied to 35 participants. After these procedures, data collection was undertaken using the adapted PDDS and a demographic data collection form. The collected data were analyzed for reliability, including stability of the scale with test-retest and internal consistency of the scale (Cronbach's alpha), and validity including construct validity of the scale with confirmatory factor analysis (CFA). Results: The parents of 210 teenagers, aged >11 and <18 years, who had been diagnosed with type 1 diabetes mellitus for at least one year were included. Of these parents, 71.9% (n=151) were mothers and 53.3% (n=112) of the children were girls. The Cronbach's a value was 0.906. The results of the CFA were.2/df=4.406, p<0.001, comparative fit test 0.704, and goodness of fit tests 0.749. The mean total PDDS score was 2.2 +/- 0.7. These results indicate that scores of 1.6 points or less was evaluated as little or no distress 1.7-2.4 as moderate distress, and >2.4 points as high distress. This showed that the majority of the parents in the study experienced moderate or severe diabetes-related distress. Conclusion: The Turkish version of the PDDS fulfilled the validity and reliability tests at an acceptable level.Öğe Sociodemographic Characteristics, Risk Factors, and Prevalence of Comorbidity among Children and Adolescents with Intellectual Disability: A Cross-sectional Study(Routledge Journals, Taylor & Francis Ltd, 2020) Uzun Cicek, Ayla; Sari, Seda Aybuke; Mercan Isik, CansuIntroduction: Intellectual disability (ID) is characterized by limitations in cognitive and adaptive functioning. The aim of this study is to examine sociodemographic characteristics, perinatal and childhood risk factors, and prevalence of psychiatric and biomedical comorbidities in children with ID. Methods: 260 patients with ID were included in the study (mean age: 8.42 +/- 3.59, 61% male, 75% mild ID). The Ankara Developmental Screening Inventory, the Wechsler Intelligence Scale for Children-Revised, and the Porteus Maze Test were used to assess the intelligence of the participants. An additional questionnaire was used to investigate their sociodemographic characteristics and birth, developmental, and medical histories. Results: Adverse perinatal/neonatal events (p < .001), biomedical comorbidities (p < .001) and seizure/convulsion history (p < .001) were strongly associated with the moderate-severe ID. The children with mild ID had more emotional-social deprivation (p = .022). Low socioeconomic situation, parental education, and teenage parenthood were risk factors for stimulus deficiency. While internalizing disorders were more common in those with mild ID and among girls, externalizing disorders were more common in those with moderate-severe ID and among boys. Conclusion: Interventions to perinatal/neonatal events may reduce the rate of moderate-severe ID. Evaluation of psychiatric and medical comorbidities and elimination of emotional-social deprivation should be fundamental components of the services offered to children with ID.Öğe Test anxiety and self-esteem in senior high school students: a cross-sectional study(TAYLOR & FRANCIS LTD, 2018) Sari, Seda Aybuke; Bilek, Gunal; Celik, EkremPurpose: In this study, it is aimed to determine the level of test anxiety and self-esteem in the high school students preparing for the university exam in Bitlis, Turkey, and to investigate the effect of test anxiety on self-esteem.Material and methods: Seven-hundred and twenty-four high school students who were preparing for the university entrance examination in Bitlis participated in the study. A questionnaire which includes socio-demographic data form, Rosenberg Self-Esteem Scale and Revised Test Anxiety Scale was prepared as an e-questionnaire for the students to fill easily and uploaded to the Bitlis State Hospital's website. Schools were called and informed for the students to fill out the e-questionnaire on the Internet.Results: The most important findings from our study are that gender is influential on test anxiety and self-esteem score and test anxiety level are negatively correlated. It was observed that female students had more test anxiety than male students and those who had higher self-esteem had less test anxiety.Conclusion: Consequently, our study shows that university entrance examination creates anxiety on students and reduces self-esteem, especially in female students.Öğe The Dark Side of Chiari Malformation(Elsevier Science Inc, 2023) Sari, Seda Aybuke; Ozum, Unal[Abstract Not Available]Öğe The Effect of Methylphenidate Treatment on Olfactory Function in Children and Adolescents With ADHD(Sage Publications Inc, 2023) Isik, Cansu Mercan; Cicek, Ayla Uzun; Altuntas, Emine Elif; Bora, Adem; Sari, Seda Aybuke; Akkus, SerdarObjective: This study aimed to research whether there is an olfactory disorder in ADHD, and if so, what is the effect of methylphenidate on this condition. Method: This is a cross-sectional study aiming to evaluate olfactory threshold, identification, discrimination and threshold, discrimination, and identification (TDI) scores in 109 children and adolescents, 33 of whom have ADHD without medication, 29 with ADHD with medication and 47 control groups. Result: In the post hoc tests, the mean odor discrimination test, the mean odor identification test, and the mean TDI scores of the unmedicated ADHD group were significantly lower than those of the other two groups, and that the mean odor threshold test scores of the medicated ADHD group were significantly lower than those of the control and unmedicated groups. Conclusion: Olfactory function could be a useful tool to monitor treatment effects and may be a promising candidate as a biomarker in ADHD.