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Yazar "Saygin, Hueseyin" seçeneğine göre listele

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    Clinical characteristics and results of 45 patients who had adrenalectomy in our clinic
    (Bayrakol Medical Publisher, 2024) Asdemir, Aydemir; Ergin, Ismail Emre; Ozturk, Abuzer; Saygin, Hueseyin; Korgali, Esat
    Aim: Laparoscopic adrenalectomy is a widely preferred method today. In recent years, many studies have reported that laparoscopic adrenalectomy requires less analgesic, less bleeding, lower complication rates and less hospitalization compared to open surgery. This study aimed to compare the surrenalectomy data performed in our clinic. Material and Methods: The data of surrenalectomies performed in our urology clinic between December 2010 and March 2022 were compared. Age, sex, side information, surgical method, and pathology results were recorded. Results: Forty five patients, aged between 26 and 83, were retrospectively analyzed. Of 45 patients who underwent surrenalectomy, 1 (2.2%) was bilateral, 25 (55.5%) were right, and 19 (42.3%) were left (42.3%) adrenalectomy. Of these cases, 18 (39.6%) were male, 27 (59.4%) were female, 31 (on one side of the bilateral) (67.4%) laparoscopic operation and 15 (on the other side of the bilateral) (32.6%) of them were open operation. Postoperative histopathological results were 17 (36.95%) adrenal cortical adenomas, 8 (17.4%) benign pheochromocytomas, 2 (4.35%) malignant pheochromocytomas, 6 (13.04%) adrenal cysts, 5 (10.86%) carcinoma metastases, 2 (4.36%) myelolipomas, 2 (4.36%) benign adrenal cortical oncocytomas, 1 (2.17%) borderline adrenal cortical oncocytoma, 1 (2.17%) oncocytic adrenal cortical carcinoma, 1 (2.17%) hydatid cyst and 1 (2.17%) adrenal tissue containing areas of bleeding and necrosis. Discussion: Histopathological results of surrenalectomy are not only significant in terms of malignancy but also important in terms of the treatment plan.
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    Utilizing cell population data for diagnosis and intensive care unit requirement prediction in Fournier gangrene patients
    (Walter De Gruyter Gmbh, 2024) Saygin, Hueseyin; Bolat, Serkan; Asdemir, Aydemir; Ozturk, Abuzer; Ergin, Ismail E.; Dogan, Halef O.; Korgali, Esat
    Objectives: It is vital to rapid diagnosis and to determine the intensive care unit (ICU) requirement early to reduce the mortality rate in Fournier gangrene (FG) patients. Cell population data (CPD) are the parameters obtained from complete blood count (CBC) analysis and related to the activation of different leukocyte subgroups. The study aimed to find reliable markers to diagnose and determine the ICU requirement using CPD. Methods: We included 24 patients and 22 healthy controls in the study. CBC analyses were performed by using a Sysmex XN-9000 series hematology analyzer. ROC analyses and group comparisons were performed to evaluate the diagnostic accuracy and prognostic value of CPD parameters in ICU requirements. Results: Statistically significant differences were observed in terms of some CPD values of lymphocytes, neutrophils, and monocytes in patients compared to healthy controls. Neutrophile-Y or reactivity index (Ne-Y or RI) (p=0.004), neutrophile-X or granularity index (Ne-X or GI) (p=0.009), monocyte-X (Mo-X) (p<0.001), and lymphocyte-WY (Ly-WY) (p<0.001) were higher in patients than controls. Ne-Y (RI) (p=0.012), Mo-X (p=0.001), Mo-Y (p=0.022), and Ne-WY (p=0.025) levels were higher in ICU patients than in non-ICU patients. Conclusions: The severity of FG disease can be determined using CPD data. Ne-Y (RI) serves as a novel and reliable biomarker for determining disease severity. In addition, the neutrophile-lymphocyte ratio can be used to rule out FG, especially in combination with other well-known clinical and diagnostic parameters.

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