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    Cost analysis of different venues for treating suicide cases presented to the Emergency Department
    (SCIENTIFIC PUBLISHERS INDIA, 2014) Guven, Fatma Mutlu Kukul; Turkdogan, Kenan Ahmet; Duman, Ali; Akpinar, Orhan; Kapci, Mucahit; Sonmez, Ertan; Coskun, Abuzer; Akpinar, Hatice; Sogut, Ozgur; Korkmaz, Ilhan
    Patients presented with poisoning-related suicide attempts is one of the most problematic cases of the emergency services. The most important reason for this being the failure to decide the department of the hospital in which these patients should be admitted to, following consultation. The objective of this study is to emphasize the cost-lowering effect of treatment and follow-up of such suicide cases in Emergency Departments (ED) instead of intensive care units. A total of 791 adult patients with suicidal attempts were retrospectively examined and their clinical and demographic data were included. In addition, the costs of their treatment in the ED, Intensive Care Unit (ICU) and Psychiatric Clinic between 01/01/2007 and 31/12/2011were compared. When patients were classified by their month of birth it was found that patients who born in January had the maximum tendency to commit suicide (n:227, 28.7%), while those born in December were the least to do so (n: 30, 3.8%). Of all the patients, 122 (15.4%) were followed-up in Anesthesia Intensive Care (AIC), 639 (80.8%) in the Emergency Department Observation Unit and 30 (3.8%) in the Psychiatric Clinic. When costs of the patients who could receive the same medical treatment in case of necessity were compared; mean cost of the patients were found to be $ 665.44 for the patients treated in AIC, $ 204.09 for patients treated in EDs and $ 186.85 for those received treatments in the psychiatric clinic. We defined that it would be profitable if the intoxication cases were followed-up in the ED observation units and that ED's could be used more effectively than ICUs.
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    Impact of C/EBP homologous protein in the diagnosis of acute pancreatitis.
    (SCIENTIFIC PUBLISHERS INDIA, 2015) Yigit, Mehmet; Turkdogan, Kenan Ahmet; Uysal, Emin; Sogut, Ozgur; Eren, Sevki Hakan; Yigit, Eda; Celik, Veysel Kenan
    Serum levels of amylase and lipase are the most widely used biochemical indicators of pancreatic inflammation. They are the basic markers used when making a diagnosis of pancreatitis. However, they are not necessarily the gold standard since the specificity and sensitivity of high amylase and lipase levels are low. The purpose of this study was to show the predictive value of C/EBP homologous protein in diagnosing acute pancreatitis. Thirty-two cases of acute pancreatitis that were admitted to the Department of Emergency Medicine of the Bezmialem Vakif University between November 2013 and July 2014 were analyzed. The diagnosis of acute pancreatitis was made based on characteristic signs and symptoms, increased serum enzyme levels, and abnormal findings on diagnostic imaging. When compared with the control group, the serum C/EBP homologous protein levels were found to be significantly increased with routine diagnostic methods in cases of acute pancreatitis. During the process of pancreatic inflammation, the level of C/EBP homologous protein increased independently in the etiopathogenesis of acute pancreatitis.
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    RED CELL DISTRIBUTION WIDTH IN CARBON MONOXIDE POISONING: RELATIONSHIP WITH MARKERS OF INEFFECTIVE ERYTHROPOIESIS, INFLAMMATION
    (CARBONE EDITORE, 2014) Turkdogan, Kenan Ahmet; Eren, Sevki Hakan; Sogut, Ozgur; Karabacak, Mustafa; Yigit, Mehmet; Gulen, Bedia; Coskun, Abuzer; Karabacak, Pinar
    Aims: Carbon monoxide (CO) poisoning is very common. Although it causes death in some cases, the pathophysiologic mechanisms that generate these fatal complications are still not fully understood. No study has directly focused on the indicators of severe complications resulting from CO poisoning; therefore, we investigated red cell distribution width (RDW), which is an indicator of systemic inflammation in patients with CO poisoning. Methods: A total of 429 patients (207 males and 222 females) who experienced CO poisoning between July 2009 and February 2013 were examined. Results: The control group comprised 23 males and 16 females (a total of 39 patients). The RDW level was significantly higher in the CO poisoning group; this increase may indicate the progression of anisocytosis due to CO poisoning. The white blood cell (WBC) level (9.9 +/- 3.4 vs 8.5 +/- 2.9 x 103/mL, respectively; p = 0.01), hemoglobin (13.7 +/- 1.7 vs 12.9 +/- 1.1 g/dl, respectively; p < 0.01) and MCHC (34.2 +/- 1.1 vs 35.1 +/- 1.6, respectively; p < 0.01) were critically higher in the group with CO poisoning. Conclusions: Our data suggest that the hypoxia in patients subjected to CO exposure resulted in significantly elevated red cell distribution width levels. The increasead red cell distribution width levels on admission may indicate the onset of complications due to CO exposure in patients without anemia.
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    Red cell distribution width in carbon monoxide poisoning: Relationship with markers of ineffective erythropoiesis, inflammation
    (Acta Medica Mediterranea, 2014) Turkdogan, Kenan Ahmet; Eren, Sevki Hakan; Sogut, Ozgur; Karabacak, Mustafa; Yigit, Mehmet; Gülen, Bedia; Coskun, Abuzer
    Aims: Carbon monoxide (CO) poisoning is very common. Although it causes death in some cases, the pathophysiologic mechanisms that generate these fatal complications are still not fully understood. No study has directly focused on the indicators of severe complications resulting from CO poisoning; therefore, we investigated red cell distribution width (RDW), which is an indicator of systemic inflammation in patients with CO poisoning. Methods: A total of 429 patients (207 males and 222 females) who experienced CO poisoning between July 2009 and February 2013 were examined. Results: The control group comprised 23 males and 16 females (a total of 39 patients). The RDW level was significantly higher in the CO poisoning group; this increase may indicate the progression of anisocytosis due to CO poisoning. The white blood cell (WBC) level (9.9 ± 3.4 vs 8.5 ± 2.9 ? 103/mL, respectively; p = 0.01), hemoglobin (13.7 ± 1.7 vs 12.9 ± 1.1 g/dl, respectively; p < 0.01) and MCHC (34.2 ± 1.1 vs 35.1 ± 1.6, respectively; p < 0.01) were critically higher in the group with CO poisoning. Conclusions: Our data suggest that the hypoxia in patients subjected to CO exposure resulted in significantly elevated red cell distribution width levels. The increasead red cell distribution width levels on admission may indicate the onset of complications due to CO exposure in patients without anemia.