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Öğe Chronic Progressive Neuro-Behcet's Disease: Magnetic Resonance Spectroscopy and Apparent Diffusion Coefficient Findings(TURKISH NEUROLOGICAL SOC, 2017) Yildiz, Ozlem Kayim; Polat, Selim; Yazgin, Duygu; Sahin, Ali; Yildiz, Bulent…Öğe Clinical, Neurophysiological and Neuroimaging Findings of Critical Illness Myopathy After COVID-19(Springernature, 2021) Yildiz, Ozlem Kayim; Yildiz, Bulent; Avci, Onur; Hasbek, Mursit; Kanat, SumeyraHypoxemic respiratory failure caused by coronavirus disease 2019 (COVID-19) may lead to prolonged intensive care unit stay and mechanical ventilation. Critically ill patients often develop intensive care unit acquired weakness (ICUAW), which is an umbrella term that encompasses critical illness polyneuropathy and critical illness myopathy. The aim of this paper is to report the clinical, neurophysiological, and radiological findings suggesting critical illness myopathy in three patients with critical COVID-19. Muscle magnetic resonance imaging may serve as a diagnostic tool for critical illness myopathy. Weaning failure and generalized muscle weakness with preserved sensation and cranial nerve function should alert physicians for ICUAW.Öğe COVID-19-associated Leukoencephalopathy Involving the Splenium of the Corpus Callosum(Galenos Publ House, 2021) Yildiz, Ozlem Kayim; Yildiz, Bulent; Hasbek, Mursit; Tatli, Gulsum Asli; Oz, Murtaza[Abstract Not Available]Öğe Crossed Cerebellar Diaschisis(TURKISH NEUROLOGICAL SOC, 2018) Yildiz, Bulent; Kose, Neslihan; Atalar, Mehmet Haydar; Caylak, Halil; Yildiz, Ozlem Kayim…Öğe Diffusion Tensor Imaging in a Patient with Joubert Syndrome(Turkish Neurological Soc, 2019) Atalar, Mehmet Haydar; Yildiz, Bulent; Yildiz, Ozlem Kayim[Abstract Not Available]Öğe Evaluation of conus medullaris level in newborn infants(Cukurova Univ, Fac Medicine, 2023) Yildiz, Bulent; Tunc, Gaffari; Soylemez, BurcakPurpose: Previous studies have reported that the conus medullaris (CM) is located between T12 and L2 in most adults, but no significant ascent has been observed during childhood. There is evidence that the normal position of the CM in an adult is acquired at birth in the majority of cases. Studies have shown that there are differences in CM levels in neonates. This situation causes problems for interventional procedures in the neonatal period. The aim of this study is to determine CM levels in preterm/term neonates using ultrasound (US).Materials and Methods: Newborn infants (gestational age: 24-43 weeks) admitted to the neonatal intensive care unit between March 2020 and June 2021 were evaluated for CM levels by the postnatal US. Infants with central nervous system abnormalities, dysmorphic features, somatic or various genetic diseases, or their parent's refusal to participate were excluded from the study.Results: Of the 189 neonates infants included in our study, 85 (44.6%) were female, 104 (55.4%) were male, 139 (73.54%) were preterm (24-36 weeks), and 50 (26.46%) were term (37-42 weeks) neonates. As a result of the US performed on the first day of 189 neonates, CM levels, 31 (16.4%) were L1, 31 (16.4%) were L1-2, and 71 (37.6%) were L2. There is a strong correlation between birth weight and birth week (r 0.84). There is a negative relationship between birth weight and CM level (r-0,20), gestational age, and CM level (r-0,23).Conclusion: Conus medullaris level was negatively correlated with gestational age and increased with advancing gestational age. In addition, the CM level shows a slower rise at 28-40 weeks of postmenstrual age and reaches the normal level (L1-L2) in the neonatal period, as in adults. Knowing the level of the CM in the newborn period will ensure that spinal procedures such as lumbar puncture to be applied to the spinal region can be performed safely.Öğe Magnetic Resonance Imaging in Delayed Carbon Monoxide Leukoencephalopathy: Diffusion and Spectroscopy Findings(TURKISH NEUROLOGICAL SOC, 2017) Yildiz, Ozlem Kayim; Yildiz, Bulent; Polat, Selim; Gokce, Seyda Figul; Bolayir, Asli; Cigdem, Burhanettin…Öğe Neuroradiologic Findings of Intracranial Hypotension: Two Cases(TURKISH NEUROLOGICAL SOC, 2017) Yildiz, Ozlem Kayim; Donmez, Recep; Gokce, Seyda Figul; Bolayir, Asli; Cigdem, Burhanettin; Balaban, Hatice; Yildiz, Bulent; Bolayir, Ertugrul; Topaktas, Suat…Öğe Subclinical atherosclerosis in fibromyalgia syndrome(Wiley, 2024) Gul, Enes; Yildiz, Bulent; Atik, Irfan; Sahin, OzlemIntroduction: Fibromyalgia syndrome (FMS) is a chronic disease of unknown pathophysiology in which inflammatory markers are not increased. The risk of cardiovascular disease is known to be raised in FMS. Determination of carotid intima-media thickness (CIMT) is essential for the early detection of cardiovascular disease risk. In this study, we aimed to investigate how FMS affects CIMT and its relationship with disease duration.Methods: This study was planned prospectively and included 20 female FMS patients and 20 healthy female controls. Detailed medical histories were obtained. Persons with a known chronic disease (diabetes mellitus, hypertension, thyroid function disorder, rheumatic disease, etc.), known atherosclerotic condition, body mass index >30 and smokers were excluded. Laboratory values of FMS patients and the control group in the last 3 months were recorded. The patients' and control groups' right and left common carotid arteries were imaged with ultrasonography.Results: There was no significant difference in laboratory values (although creatinine was different, it was within the normal range in both groups). The mean right common carotid artery intima-media thickness was 0.5 (+/- 0.07) mm in the patient group and 0.43 (+/- 0.05) mm in the control group (p = .005). The mean left common carotid artery intima-media thickness was 0.5 (+/- 0.06) mm in the patient group and 0.43 (+/- 0.05) mm in the control group (p = .001). Carotid intima-media thickness values were significantly higher in the patient group than in the control group.Conclusions: Although FMS is not an inflammatory disease, it causes endothelial dysfunction and atherosclerosis.Öğe The role of systemic immune inflammatory index in showing active lesion in patients with multiple sclerosis SII and other inflamatuar biomarker in radiological active multiple sclerosis patients(Bmc, 2023) Gokce, Seyda Figul; Bolayir, Asli; Cigdem, Burhanettin; Yildiz, BulentBackground Multiple sclerosis (MS) has two pathophysiological processes, one inflammatory and the other degenerative. We investigated the relationship between active lesions on magnetic resonance imaging showing the inflammatory phase in MS patients and serum parameters that can be used as inflammatory biomarkers. Thus, we aim to detect the inflammatory period in clinical and radiological follow-up and to reveal the period in which disease-modifying treatments are effective with serum parameters. Methods One hundred eighty-six MS patients presented to our hospital between January 2016 and November 2021 and 94 age- and sex-matched healthy volunteers were recruited for our study. While 99 patients had active lesions on magnetic resonance imaging, 87 patients did not have any active lesions. Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) were determined. The SII (systemic immune inflammatory index) value was calculated according to the platelet X neutrophil/lymphocyte ratio formula. Results NLR, MLR, PLR and SII values were found to be statistically significantly higher in MS patients than in the control group. The NLR, MLR, PLR and SII were higher in the active group with gadolonium than in the group without active lesions. In addition, the cutoff values that we can use to determine the presence of active lesions were 1.53, 0.18, 117.15, and 434.45 for NLR, MLR PLR and SII, respectively. Conclusions We found that all parameters correlated with radiological activity. In addition, we showed that we can detect the inflammatory period with high sensitivity and specificity with the cutoff value used for SII and PLR. Among these easily accessible and inexpensive evaluations, we concluded that SII, including the values in the PLR formula, can come to the fore.
