Pathological Prognostic Features and Analysis of Renal Cell Carcinoma

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dc.contributor.authorÖztürk, Sena
dc.contributor.authorÇelikgün, Serkan
dc.contributor.authorYeldir, Neşe
dc.date.accessioned2025-05-04T16:26:31Z
dc.date.available2025-05-04T16:26:31Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractRenal cell carcinomas is 2-3% of all adult cancers. Kidney cancer is currently the seventh most common cancer in men and the tenth most common in women 1. There were 19,3 million new cancer diagnoses and 10 million cancer deaths worldwide in 2020 2. Survival in renal cell carcinomas has a strong correlation with the stage of diagnosis. 5-year survival in stage 1 tumors is 93%, 72,5% in cases with local lymph node metastases and 12% in metastatic carcinomas cases 3. There is an inverse correlation between age / tumor size and survival. Metastatic lymph node, tumor necrosis and adipose tissue invasion are associated with poor prognosis 4. The study is including 179 renal cell carcinoma cases. The clinical and pathological datas of these cases were retrospectively analyzed from the Cumhuriyet University Hospital patient system. The distribution sex of cases are 111 males (62%) and 68 females (38%). The mean age of the 179 cases was 58,5±11,9 years (range of 21-90). The mean tumor diameter is 5,7±3,4 (range of 1-19 cm). The nuclear grades of cases are 53,1% with low grade and 46,8% with high grade. Radical nephrectomies were evaluated for vascular invasion, ureter invasion, capsule/adipose tissue invasion, lymph node metastasis and adrenal gland metastasis. There is a statistically significant relationship between nuclear grade and vein invasion, microvascular invasion, capsule/adipose tissue invasion (p
dc.description.abstract[No abstract available]
dc.identifier.doi10.7197/cmj.1216497
dc.identifier.doihttps://doi.org/10.7197/cmj.1216497
dc.identifier.endpage474
dc.identifier.issn1305-0028
dc.identifier.issue4
dc.identifier.startpage470
dc.identifier.urihttps://hdl.handle.net/20.500.12418/32770
dc.identifier.volume44
dc.language.isoen
dc.publisherSivas Cumhuriyet University
dc.relation.ispartofCumhuriyet Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250504
dc.subjectRenal cell carcinoma
dc.subjectvascular invasion
dc.subjectnuclear grade
dc.subjecttumor diameters
dc.titlePathological Prognostic Features and Analysis of Renal Cell Carcinoma
dc.typeResearch Article

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