Synthesis, Characterization and Biological Activities of Novel Chiral Bis 1,2-diolcarbothioamides

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dc.contributor.authorKaratepe, Arzu
dc.contributor.authorKoparır, Pelin
dc.contributor.authorDaştan, Taner
dc.contributor.authorİnci, Şule
dc.contributor.authorKeser, Serhat
dc.contributor.authorÇetin, Ahmet
dc.date.accessioned2025-05-04T16:24:44Z
dc.date.available2025-05-04T16:24:44Z
dc.date.issued2024
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstract2,2'- bis(N-aryl-alkylhydrazine-1-carbothioamide (T1–5) were obtained by the interaction of (2R,3R)-2,3-dihydroxybutanedihydrazide (1) with five different isothiocyanate alkyl(aryl) derivatives. The structures of the final compounds were confirmed by elemental analyses, FT-IR, ¹H-NMR and ¹³C-NMR. The antioxidant, antimicrobial and anticancer properties of the synthesized compounds were also investigated. Three of the triazole derivatives with p-tolyl, benzyl and phenyl substituents (T3–5) displayed good antioxidant and anticancer activity in comparison to the standards.
dc.description.abstract[No abstract available]
dc.identifier.doi10.54565/jphcfum.1539891
dc.identifier.doihttps://doi.org/10.54565/jphcfum.1539891
dc.identifier.endpage81
dc.identifier.issn2651-3080
dc.identifier.issn2651-3080
dc.identifier.issue2
dc.identifier.startpage73
dc.identifier.urihttps://hdl.handle.net/20.500.12418/32520
dc.identifier.volume7
dc.language.isoen
dc.publisherNiyazi BULUT
dc.relation.ispartofJournal of Physical Chemistry and Functional Materials
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250504
dc.subjectCarbothioamide
dc.subjectanticancer
dc.subjectantioxidant
dc.subjectantimicrobial
dc.titleSynthesis, Characterization and Biological Activities of Novel Chiral Bis 1,2-diolcarbothioamides
dc.typeResearch Article

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