Evaluation of QT Interval of Patients Using Muscle Relaxants Under General Anesthesia, Randomized Clinical Trial

Basit Öğe Kaydı
dc.contributor.authorKurt, Bekir
dc.contributor.authorGündoğdu, Oğuz
dc.contributor.authorAvcı, Onur
dc.contributor.authorGürsoy, Sinan
dc.contributor.authorKol, İclal Özdemir
dc.contributor.authorKaygusuz, Kenan
dc.contributor.authorİsbir, Cemil
dc.date.accessioned2025-05-04T16:26:29Z
dc.date.available2025-05-04T16:26:29Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: The aim of the study was to investigate the effects of rocuronium, mivacurium, and atracurium on arrhythmia markers, QT interval, and QT dispersion (QTd).Method: Ninety patients scheduled for septorhinoplasty were randomly assigned to one of three groups of 30. During the induction of anesthesia, muscle relaxants of 0.6 mg/kg rocuronium in Group R, 0.2 mg/kg mivacurium in Group M, and 0.5 mg/kg atracurium in Group A were employed. Mean blood pressure (MAP), heart rate (HR), and electrocardiogram (ECG) values were measured before induction of anesthesia (T0), immediately after induction of anesthesia (T1), at 1 minute (T2), 5 minutes (T3), 10 minutes (T4) and 15 minutes (T5) after muscle relaxant administration, and QT, corrected QT (QTc), QTd and corrected QTd (QTcd) intervals were recorded. Results: When the groups were compared in terms of QTcd values, the difference between mivacurium and atracurium was significant in terms of T5 values, and atracurium (T5) QTcd was found to be shorter (p<0.05). Group M had 5 of the 6 measures with pathological QTc prolongation.Conclusions: Because the prevalence of pathological QTc is greater in mivacurium, further clinical trials should be conducted to challenge the use of mivacurium in individuals with a long QT interval.
dc.description.abstract[No abstract available]
dc.identifier.doi10.7197/cmj.1056331
dc.identifier.doihttps://doi.org/10.7197/cmj.1056331
dc.identifier.endpage86
dc.identifier.issn1305-0028
dc.identifier.issue1
dc.identifier.startpage80
dc.identifier.urihttps://hdl.handle.net/20.500.12418/32731
dc.identifier.volume44
dc.language.isoen
dc.publisherSivas Cumhuriyet University
dc.relation.ispartofCumhuriyet Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250504
dc.subjectatracurium
dc.subjectmivacurium
dc.subjectrocuronium
dc.subjectelectrocardiography
dc.subjectqt interval
dc.titleEvaluation of QT Interval of Patients Using Muscle Relaxants Under General Anesthesia, Randomized Clinical Trial
dc.typeResearch Article

Dosyalar

Koleksiyon

DergiPark